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Understanding metabolic flexibility: a potential key to unlocking metabolic therapies in amyotrophic lateral sclerosis?
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作者 scott p.allen 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第9期1654-1655,共2页
The role of metabolism in amyotrophic lateral sclerosis(ALS):ALS,is a predominantly sporadic,neurological disorder resulting in degeneration of both upper and lower motor neurons,resulting in the progressive failure o... The role of metabolism in amyotrophic lateral sclerosis(ALS):ALS,is a predominantly sporadic,neurological disorder resulting in degeneration of both upper and lower motor neurons,resulting in the progressive failure of the neuromuscular system.The lifetime risk factor for developing ALS sits between 1 in 300 and 1 in 400.However,due to the speed of the disease course(2–3 years post-diagnosis)and the lack of effective therapies,ALS is still classified as a rare disease. 展开更多
关键词 METABOLISM amyotrophic DEGENERATION
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