Capacitively coupled shortwave radiofrequency fields(13.56 MHz)resistively heat low concentrations(~1 ppm)of gold nanoparticles with a thermal power dissipation of~380 kW/g of gold.Smaller diameter gold nanoparticles(...Capacitively coupled shortwave radiofrequency fields(13.56 MHz)resistively heat low concentrations(~1 ppm)of gold nanoparticles with a thermal power dissipation of~380 kW/g of gold.Smaller diameter gold nanoparticles(<50 nm)heat at nearly twice the rate of larger diameter gold nanoparticles(≥50 nm),which is attributed to the higher resistivity of smaller gold nanostructures.A Joule heating model has been developed to explain this phenomenon and provides critical insights into the rational design and engineering of nanoscale materials for noninvasive thermal therapy of cancer.展开更多
基金the Radiowave Therapy Fund and Institutional Core Grant#CA16672 High-Resolution Electron Microscopy Facility,UTMDACC.The authors are grateful to Richard E.Smalley,Boris Yakobson,Bruce Johnson,Robert Curl,and George M.Whitesides for helpful discussions and suggestions.The authors are also grateful to Nanospectra Biosciences, Inc., Donald Payne, and Glenn Goodrich for providing gold nanoshell samples and Precision Colloids, LLC for providing silica samples.
文摘Capacitively coupled shortwave radiofrequency fields(13.56 MHz)resistively heat low concentrations(~1 ppm)of gold nanoparticles with a thermal power dissipation of~380 kW/g of gold.Smaller diameter gold nanoparticles(<50 nm)heat at nearly twice the rate of larger diameter gold nanoparticles(≥50 nm),which is attributed to the higher resistivity of smaller gold nanostructures.A Joule heating model has been developed to explain this phenomenon and provides critical insights into the rational design and engineering of nanoscale materials for noninvasive thermal therapy of cancer.
