Objective: To evaluate the effects of hippocampal damages on P300 of event-re lated potentials (ERPs). Methods: ERPs were recorded over about 8 months using t he auditory oddball paradigm in a patient with bilateral h...Objective: To evaluate the effects of hippocampal damages on P300 of event-re lated potentials (ERPs). Methods: ERPs were recorded over about 8 months using t he auditory oddball paradigm in a patient with bilateral hippocampal lesions con firmed on brain magnetic resonance imaging. Findings were compared with those from clinical electroencephalography (period ic lateralized epileptiform discharges (PLEDs) or bilateral independent PLEDs (B IPLE- Ds). The patient displayed no marked clinical symptoms aside from mild memory impairment during this time, and was able to fully perform the oddball task.Resu lts: Clearly identifiable P300 were present in all recordings.Furthermore, incre ases in the number of right PLEDs were significantly correlated with increases i n P300 latency.Conclusions: Two key results were apparent. First, the appearance of P300 in all ERP recordings supports the suggestion that the hippocampus is n ot indispensable for P300 generation.Sec- ond, the correlation between the number of PLEDs and P300 latency supports the suggestion that the hippocampus affect the components of P300 latency. Signific ance: This case thus offers very suggestive evidence regarding the generation of P300.展开更多
Aim: The purpose of this study was to determine the prevalence of intestinal metaplasia of the gastric cardia in Japanese patients with Helicobacter pylori infection. Methods: One hundred and fifty seven patients with...Aim: The purpose of this study was to determine the prevalence of intestinal metaplasia of the gastric cardia in Japanese patients with Helicobacter pylori infection. Methods: One hundred and fifty seven patients with H. pylori infection participated in this study. Four biopsy specimens were taken from antrum, lesser and greater curvatures of stomach, and cardia for histological examination. The patients were divided into three groups: those ≤39 years of age (group A), those 40-59 years old (group B), and those ≥60 years of age (group C). Results: The proportions of the patients with intestinal metaplasia of the gastric cardia in the three groups were 12, 39, and 65%, respectively. Their intestinal metaplasia of gastric cardia scores were 0.2, 0.54, and 0.81, respectively (significant difference among groups A, B, and C : p < 0.05), according to the updated Sydney classification. Conclusion: The prevalence of intestinal metaplasia of the gastric cardia and carditis in Japanese patients with H. pylori infection was similar to that of metaplasia of antrum and lesser curvature of the stomach.展开更多
文摘Objective: To evaluate the effects of hippocampal damages on P300 of event-re lated potentials (ERPs). Methods: ERPs were recorded over about 8 months using t he auditory oddball paradigm in a patient with bilateral hippocampal lesions con firmed on brain magnetic resonance imaging. Findings were compared with those from clinical electroencephalography (period ic lateralized epileptiform discharges (PLEDs) or bilateral independent PLEDs (B IPLE- Ds). The patient displayed no marked clinical symptoms aside from mild memory impairment during this time, and was able to fully perform the oddball task.Resu lts: Clearly identifiable P300 were present in all recordings.Furthermore, incre ases in the number of right PLEDs were significantly correlated with increases i n P300 latency.Conclusions: Two key results were apparent. First, the appearance of P300 in all ERP recordings supports the suggestion that the hippocampus is n ot indispensable for P300 generation.Sec- ond, the correlation between the number of PLEDs and P300 latency supports the suggestion that the hippocampus affect the components of P300 latency. Signific ance: This case thus offers very suggestive evidence regarding the generation of P300.
文摘Aim: The purpose of this study was to determine the prevalence of intestinal metaplasia of the gastric cardia in Japanese patients with Helicobacter pylori infection. Methods: One hundred and fifty seven patients with H. pylori infection participated in this study. Four biopsy specimens were taken from antrum, lesser and greater curvatures of stomach, and cardia for histological examination. The patients were divided into three groups: those ≤39 years of age (group A), those 40-59 years old (group B), and those ≥60 years of age (group C). Results: The proportions of the patients with intestinal metaplasia of the gastric cardia in the three groups were 12, 39, and 65%, respectively. Their intestinal metaplasia of gastric cardia scores were 0.2, 0.54, and 0.81, respectively (significant difference among groups A, B, and C : p < 0.05), according to the updated Sydney classification. Conclusion: The prevalence of intestinal metaplasia of the gastric cardia and carditis in Japanese patients with H. pylori infection was similar to that of metaplasia of antrum and lesser curvature of the stomach.
