Objective To report on the treatment with recombinant FSH of an azoos permic no rmogonadotropic patient with a Y-chromosome microdeletion. Design Case report. Setting An assisted reproduction center. Patient(s) A 32-y...Objective To report on the treatment with recombinant FSH of an azoos permic no rmogonadotropic patient with a Y-chromosome microdeletion. Design Case report. Setting An assisted reproduction center. Patient(s) A 32-year-old patient with azoospermia. Intervention(s) Histological testicular biopsy, Ychromosome screen ing, FSH treatment, and intracytoplasmic sperm injection. Main outcome measure(s ) Fertilization, embryo development, pregnancy, and delivery. Result(s) After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patients ejaculate and used for IVF, resulting in a successful twin pr egnancy and the delivery of two healthy girls. Conclusion(s) In this study, trea tment with gonadotropins promoted the spermatogenesis process and led to the pro duction of spermatozoa in a normogonadotropicazoospermic patient.展开更多
文摘Objective To report on the treatment with recombinant FSH of an azoos permic no rmogonadotropic patient with a Y-chromosome microdeletion. Design Case report. Setting An assisted reproduction center. Patient(s) A 32-year-old patient with azoospermia. Intervention(s) Histological testicular biopsy, Ychromosome screen ing, FSH treatment, and intracytoplasmic sperm injection. Main outcome measure(s ) Fertilization, embryo development, pregnancy, and delivery. Result(s) After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patients ejaculate and used for IVF, resulting in a successful twin pr egnancy and the delivery of two healthy girls. Conclusion(s) In this study, trea tment with gonadotropins promoted the spermatogenesis process and led to the pro duction of spermatozoa in a normogonadotropicazoospermic patient.
