期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
A 3D-printable device allowing fast and reproducible longitudinal preparation of mouse intestines
1
作者 Beckey DeLucia sergey samorezov +5 位作者 Megan T.Zangara Rachel L.Markley Lucas J.Osborn Karlee B.Schultz Christine McDonald Jan Claesen 《Animal Models and Experimental Medicine》 CSCD 2022年第2期189-196,共8页
Accurate and reproducible analysis of murine small and large intestinal tissue is key for preclinical models involving intestinal pathology.Currently,there is no easily ac-cessible,standardized method that allows rese... Accurate and reproducible analysis of murine small and large intestinal tissue is key for preclinical models involving intestinal pathology.Currently,there is no easily ac-cessible,standardized method that allows researchers of different skill levels to con-sistently dissect intestines in a time-efficient manner.Here,we describe the design and use of the 3D-printed“Mouse Intestinal Slicing Tool”(MIST),which can be used to longitudinally dissect murine intestines for further analysis.We benchmarked the MIST against a commonly used procedure involving scissors to make a longitudinal cut along the intestines.Use of the MIST halved the time per mouse to prepare the intestines and outperformed alternative methods in smoothness of the cutting edge and overall reproducibility.By sharing the plans for printing the MIST,we hope to contribute a uniformly applicable method for saving time and increasing consistency in studies of the mouse gastrointestinal tract. 展开更多
关键词 ADENOMA DISSECTION i ntestines mice PRINTING three-dimensional reproducibility of results
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部