Dear Editor,Breast cancer is a leading type of cancer in women,the treatment of basal type,including triple negative breast cancer(TNBC),remains challenging due to its aggressive behaviors and lack of targeted therape...Dear Editor,Breast cancer is a leading type of cancer in women,the treatment of basal type,including triple negative breast cancer(TNBC),remains challenging due to its aggressive behaviors and lack of targeted therapeutic options1.F-box proteins(FBPs)can serve as either oncogenes or tumor suppressors depending on their substrates,and various studies have been conducted on their involvement in different types of cancer and play significant roles in cancer development and progression2.However,the related mechanisms and targets of F-box protein 15(FBX015)are still remain unclear in human breast cancers.展开更多
基金This research was supported by the Bio&Medical Technology Development Program of the National Research Foundation(NRF)funded by the Korean government(MSIT)(No.2019M3E5D1A01069361)by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2019R1A2C2087551)。
文摘Dear Editor,Breast cancer is a leading type of cancer in women,the treatment of basal type,including triple negative breast cancer(TNBC),remains challenging due to its aggressive behaviors and lack of targeted therapeutic options1.F-box proteins(FBPs)can serve as either oncogenes or tumor suppressors depending on their substrates,and various studies have been conducted on their involvement in different types of cancer and play significant roles in cancer development and progression2.However,the related mechanisms and targets of F-box protein 15(FBX015)are still remain unclear in human breast cancers.
