Introduction: Testing for the presence of micro-organisms in the urinary tract, in order to diagnose asymptomatic bacteriuria or symptomatic urinary tract infections (UTI), is very common at all levels of health care....Introduction: Testing for the presence of micro-organisms in the urinary tract, in order to diagnose asymptomatic bacteriuria or symptomatic urinary tract infections (UTI), is very common at all levels of health care. This study was conducted to assess the diagnostic values for bacteriuria and pyuria and evaluate their roles in therapeutic decision making. Methods: A total of 1770 urine samples were obtained by simple randomized method from the central Laboratory of the Ali-ebne-Abitaleb Hospital (Zahedan, Iran). Urine culture was done to compare urine microscopy profiles. Sensitivity, specificity, positive and negative predictive values of the findings of urine analysis was described. Results: 1055 (59.6%) of the cases were females. 13% (230/1770) of patients had positive urine cultures. The most prevalent cultured micro-organism was E. coli (63%). Sensitivity, specificity, positive and negative predictive values of microscopic pyuria were 85%, 88%, 51%, 97%, respectively. As the same for bacteriuria, these calculations were 97%, 98%, 90%, 99% and for the category with both bacteriuria and pyuria were 82%, 99%, 95%, 97%, respectively. Conclusion: According to the results, it is concluded that the urine microscopy features seems to be useful to exclude the presence of infection if the results of both bacteriuria and pyuria are negative, but positive test results have to be confirmed.展开更多
We investigated the efficacy of oral desmopressin in the treatment of adult nocturia. In an analytical study between 2007-2009 in Zahedan-Iran, Thirty patients ≥55 years with verified nocturia (≥two voids/night) wer...We investigated the efficacy of oral desmopressin in the treatment of adult nocturia. In an analytical study between 2007-2009 in Zahedan-Iran, Thirty patients ≥55 years with verified nocturia (≥two voids/night) were enrolled. Patients with a history of an obstructive cause of nocturia, those with diseases getting worse by the anti-diuretic affect of desmopressin and those with well-defined curable causes (e.g. cystitis) were excluded. Patients received 0.2 mg of oral desmopressin at bed time for a period of 3 weeks. p < 0.05 was taken as the significant level. All 30 patients enrolled completed the trial. Fourteen (47 %) patients receiving desmopressin had fewer than half the number of nocturnal voids relative to base line (p < 0.001). The mean number of nocturnal voids decreased from 4.6 to 2.4 (p < 0.001). Fatigue (10%), headache (3%) and dizziness (3%) were reported. All adverse events were of mild intensity and there were no instances of hyponatremia. Oral desmopressin is an effective treatment in patients with nocturia and is well-tolerated.展开更多
文摘Introduction: Testing for the presence of micro-organisms in the urinary tract, in order to diagnose asymptomatic bacteriuria or symptomatic urinary tract infections (UTI), is very common at all levels of health care. This study was conducted to assess the diagnostic values for bacteriuria and pyuria and evaluate their roles in therapeutic decision making. Methods: A total of 1770 urine samples were obtained by simple randomized method from the central Laboratory of the Ali-ebne-Abitaleb Hospital (Zahedan, Iran). Urine culture was done to compare urine microscopy profiles. Sensitivity, specificity, positive and negative predictive values of the findings of urine analysis was described. Results: 1055 (59.6%) of the cases were females. 13% (230/1770) of patients had positive urine cultures. The most prevalent cultured micro-organism was E. coli (63%). Sensitivity, specificity, positive and negative predictive values of microscopic pyuria were 85%, 88%, 51%, 97%, respectively. As the same for bacteriuria, these calculations were 97%, 98%, 90%, 99% and for the category with both bacteriuria and pyuria were 82%, 99%, 95%, 97%, respectively. Conclusion: According to the results, it is concluded that the urine microscopy features seems to be useful to exclude the presence of infection if the results of both bacteriuria and pyuria are negative, but positive test results have to be confirmed.
文摘We investigated the efficacy of oral desmopressin in the treatment of adult nocturia. In an analytical study between 2007-2009 in Zahedan-Iran, Thirty patients ≥55 years with verified nocturia (≥two voids/night) were enrolled. Patients with a history of an obstructive cause of nocturia, those with diseases getting worse by the anti-diuretic affect of desmopressin and those with well-defined curable causes (e.g. cystitis) were excluded. Patients received 0.2 mg of oral desmopressin at bed time for a period of 3 weeks. p < 0.05 was taken as the significant level. All 30 patients enrolled completed the trial. Fourteen (47 %) patients receiving desmopressin had fewer than half the number of nocturnal voids relative to base line (p < 0.001). The mean number of nocturnal voids decreased from 4.6 to 2.4 (p < 0.001). Fatigue (10%), headache (3%) and dizziness (3%) were reported. All adverse events were of mild intensity and there were no instances of hyponatremia. Oral desmopressin is an effective treatment in patients with nocturia and is well-tolerated.
