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生肌化瘀凝胶质量标准研究 被引量:2
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作者 张玉萱 徐玲玲 +2 位作者 刘爱军 单陈伟 廖雪清 《中国药业》 CAS 2023年第9期61-65,共5页
目的建立生肌化瘀凝胶的质量控制方法。方法采用薄层色谱法对样品中的血竭、大黄、白芷、丹参、紫草、黄芪进行定性鉴别;采用高效液相色谱法测定样品中血竭素和大黄酚的含量,血竭素和大黄酚的色谱柱分别为Agilent Zorbax-SB-C18柱(250 m... 目的建立生肌化瘀凝胶的质量控制方法。方法采用薄层色谱法对样品中的血竭、大黄、白芷、丹参、紫草、黄芪进行定性鉴别;采用高效液相色谱法测定样品中血竭素和大黄酚的含量,血竭素和大黄酚的色谱柱分别为Agilent Zorbax-SB-C18柱(250 mm×4.6 mm,15μm)和Zorbax Eclipse XDB-C18柱(250 mm×4.6 mm,5μm),流动相分别为乙腈-0.05 mol/L磷酸二氢钠溶液(50∶50,V/V)和甲醇-0.1%磷酸水溶液(85∶15,V/V),流速为1 mL/min,检测波长分别为440 nm和254 nm,柱温分别为40℃和30℃,进样量为10μL。结果薄层色谱图中特征斑点显色清晰,分离度好,且阴性对照无干扰。血竭素、大黄酚的质量浓度分别在0.02585~0.09048 mg/mL和0.001~0.060 mg/mL范围内与峰面积线性关系良好(r=0.9999,n=6);精密度、稳定性、重复性试验结果的RSD均低于3.0%;平均加样回收率分别为101.88%和96.82%,RSD分别为2.50%和0.79%(n=9)。6批样品中,血竭素、大黄酚的平均含量分别为0.0396 mg/mL和0.0037 mg/mL。结论该方法专属性强、结果准确,可用于生肌化瘀凝胶的质量控制。 展开更多
关键词 生肌化瘀凝胶 血竭素 大黄酚 薄层色谱法 高效液相色谱法 质量控制
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Prediction of cutting forces in ball-end milling of 2.5D C/C composites 被引量:3
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作者 shan chenwei Wang Xiao +1 位作者 Yang Xuanxuan Lyu Xiaobo 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2016年第3期824-830,共7页
Machining of carbon/carbon (C/C) composite materials is difficult to carry out due to its high specific stiffness, brittleness, anisotropic, non-homogeneous and low thermal conductivity, which can result in tear, bu... Machining of carbon/carbon (C/C) composite materials is difficult to carry out due to its high specific stiffness, brittleness, anisotropic, non-homogeneous and low thermal conductivity, which can result in tear, burr, poor surface quality and rapid wear of cutters. Accurate and fast pre- diction of cutting forces is important for milling C/C composite materials with high quality. This paper presents an alternative cutting force model involving the influences of the directions of fiber. Based on the calculated and experimental results, the cutting forces" coefficients of 2.5D CC com- posites are evaluated using multiple linear regression method. Verification experiment has been car- ried out through a group of orthogonal tests. Results indicate that the proposed nmdel is reliable and can be used to predict the cutting forces in ball-end milling of 2.5D C/C composites. 展开更多
关键词 Ball-end milling C/C composites Culling force Fiber orientationOrthogonal test
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