目的检索、获取全髋关节置换患者术后早期抗阻训练的相关证据,并对最佳证据进行总结。方法使用计算机检索BMJ Best Practice、UpToDate、澳大利亚乔安娜布里格斯研究所循证卫生保健中心数据库、美国国立临床诊疗指南数据库、英国国家医...目的检索、获取全髋关节置换患者术后早期抗阻训练的相关证据,并对最佳证据进行总结。方法使用计算机检索BMJ Best Practice、UpToDate、澳大利亚乔安娜布里格斯研究所循证卫生保健中心数据库、美国国立临床诊疗指南数据库、英国国家医疗保健优化研究所指南库、苏格兰校际指南网络、新西兰指南协作组网站、Cochrane Library、PubMed、EBSCO、荷兰学术期刊全文数据库、中国知网、万方、维普和中国生物医学文献数据库及骨科相关网站关于全髋关节置换患者术后早期抗阻训练的相关证据,包括指南、最佳实践、临床决策、系统评价、专家共识及相关原始研究,检索时限为2009年1月1日—2020年4月20日。由3名研究者对纳入的文献质量进行评价,并提取符合质量标准的文献证据。结果共纳入文献20篇,包括指南2篇、临床决策1篇、随机对照试验研究6篇、系统评价7篇、专家共识2篇、病例对照研究1篇、队列研究1篇。结合专业人员的判断,围绕抗阻训练的评估、时间、强度、方式、地点、方案、不良反应及监测8个方面,共汇总13条最佳证据。结论总结的关于全髋关节置换患者术后早期抗阻训练的最佳证据,可为医护人员的临床应用提供循证依据。展开更多
OBJECTIVE:To investigate the effect of Bushen Jianpi formula(BSJP)therapy on survival of the patients with moderate and advanced hepatocellular carcinoma(HCC).METHODS:This was a five-year retrospective study,enrolling...OBJECTIVE:To investigate the effect of Bushen Jianpi formula(BSJP)therapy on survival of the patients with moderate and advanced hepatocellular carcinoma(HCC).METHODS:This was a five-year retrospective study,enrolling 209 adult patients with moderate and advanced HCC patients.Log-rank test,Cox regression analysis and Kaplan-Meier analysis was applied to analyze the data.RESULTS:The outcome of single-factor Kaplan-Meier analysis and Log-rank test showed that stage of Barcelona-clinic liver cancer(BCLC),locoregional therapy and BSJP therapy were three factors that dominantly influenced the survival of moderate and advanced HCC patients(P<0.05).In Cox multiple-factor regression analysis,lower BCLC staging(RR=2.016;P=0.000),locoregional therapy(RR=0.611;P=0.011)and BSJP therapy(RR=0.684;P=0.044)were the independent protective factors affecting survival of patients,and BSJP exerted a more significant effect on patients at BCLC-C stage(RR=0.513;P=0.002).CONCLUSION:BSJP therapy and locoregional therapy both contributed to prolonged survival for moderate and advanced HCC patients.展开更多
文摘目的检索、获取全髋关节置换患者术后早期抗阻训练的相关证据,并对最佳证据进行总结。方法使用计算机检索BMJ Best Practice、UpToDate、澳大利亚乔安娜布里格斯研究所循证卫生保健中心数据库、美国国立临床诊疗指南数据库、英国国家医疗保健优化研究所指南库、苏格兰校际指南网络、新西兰指南协作组网站、Cochrane Library、PubMed、EBSCO、荷兰学术期刊全文数据库、中国知网、万方、维普和中国生物医学文献数据库及骨科相关网站关于全髋关节置换患者术后早期抗阻训练的相关证据,包括指南、最佳实践、临床决策、系统评价、专家共识及相关原始研究,检索时限为2009年1月1日—2020年4月20日。由3名研究者对纳入的文献质量进行评价,并提取符合质量标准的文献证据。结果共纳入文献20篇,包括指南2篇、临床决策1篇、随机对照试验研究6篇、系统评价7篇、专家共识2篇、病例对照研究1篇、队列研究1篇。结合专业人员的判断,围绕抗阻训练的评估、时间、强度、方式、地点、方案、不良反应及监测8个方面,共汇总13条最佳证据。结论总结的关于全髋关节置换患者术后早期抗阻训练的最佳证据,可为医护人员的临床应用提供循证依据。
基金the Action three years plan for Shanghai Chinese medicine industry(No.ZY3-LCPT-1-1001,ZY3-RCPY-3-1011)National Natural Science Foundation of China(No.81302891)。
文摘OBJECTIVE:To investigate the effect of Bushen Jianpi formula(BSJP)therapy on survival of the patients with moderate and advanced hepatocellular carcinoma(HCC).METHODS:This was a five-year retrospective study,enrolling 209 adult patients with moderate and advanced HCC patients.Log-rank test,Cox regression analysis and Kaplan-Meier analysis was applied to analyze the data.RESULTS:The outcome of single-factor Kaplan-Meier analysis and Log-rank test showed that stage of Barcelona-clinic liver cancer(BCLC),locoregional therapy and BSJP therapy were three factors that dominantly influenced the survival of moderate and advanced HCC patients(P<0.05).In Cox multiple-factor regression analysis,lower BCLC staging(RR=2.016;P=0.000),locoregional therapy(RR=0.611;P=0.011)and BSJP therapy(RR=0.684;P=0.044)were the independent protective factors affecting survival of patients,and BSJP exerted a more significant effect on patients at BCLC-C stage(RR=0.513;P=0.002).CONCLUSION:BSJP therapy and locoregional therapy both contributed to prolonged survival for moderate and advanced HCC patients.
