The disease caused by the SARS-CoV-2 virus has spread very rapidly th<span "=""><span>rough</span><span>out the world, causing various clinical manifestations and affecting sever...The disease caused by the SARS-CoV-2 virus has spread very rapidly th<span "=""><span>rough</span><span>out the world, causing various clinical manifestations and affecting several organs and systems. However, the possibility of vertical transmission of C</span><span>OVID-19 in symptomatic pregnant women has been questioned. The aim of this work was to report cases of possible vertical transmission in pregnant women affected by the SARS-CoV-2 virus, as well as its clinical repercussions on the newborn. In this paper, we conducted a cross-sectional retrospective study by analyzing medical records of pregnant women admitted at the military hospital, </span></span><span>in </span><span>Rio de Janeiro, Brazil, diagnosed with COVID-19 and who had positive newborns. To evaluate epidemiological data, clinical manifestations, laborator</span><span>ial</span><span> and histopathological changes </span><span>were </span><span>related to </span><span>such</span><span> vertical transmission. Only six tested newborns </span><span>were </span><span>positive for COVID-19. The mothers had no respiratory symptoms, and the gestational age was at term, except for one newborn born prematurely due to detection of pericadial effusion. Three neonates had respiratory symptoms, requiring ventilatory support. None of the mothers or newborns died. During the pandemic, possible vertical transmission cases of infected pregnant women in the third trimester of pregnancy were observed. According to the case reports published in the literature, they illustrate phenotypes of neonatal involvement with varied clinical manifestations and severity;however, further scientific studies are needed to prove the effective vertical transmission of SARS-C</span><span>o</span><span>V-2 in positive pregnant women.展开更多
文摘The disease caused by the SARS-CoV-2 virus has spread very rapidly th<span "=""><span>rough</span><span>out the world, causing various clinical manifestations and affecting several organs and systems. However, the possibility of vertical transmission of C</span><span>OVID-19 in symptomatic pregnant women has been questioned. The aim of this work was to report cases of possible vertical transmission in pregnant women affected by the SARS-CoV-2 virus, as well as its clinical repercussions on the newborn. In this paper, we conducted a cross-sectional retrospective study by analyzing medical records of pregnant women admitted at the military hospital, </span></span><span>in </span><span>Rio de Janeiro, Brazil, diagnosed with COVID-19 and who had positive newborns. To evaluate epidemiological data, clinical manifestations, laborator</span><span>ial</span><span> and histopathological changes </span><span>were </span><span>related to </span><span>such</span><span> vertical transmission. Only six tested newborns </span><span>were </span><span>positive for COVID-19. The mothers had no respiratory symptoms, and the gestational age was at term, except for one newborn born prematurely due to detection of pericadial effusion. Three neonates had respiratory symptoms, requiring ventilatory support. None of the mothers or newborns died. During the pandemic, possible vertical transmission cases of infected pregnant women in the third trimester of pregnancy were observed. According to the case reports published in the literature, they illustrate phenotypes of neonatal involvement with varied clinical manifestations and severity;however, further scientific studies are needed to prove the effective vertical transmission of SARS-C</span><span>o</span><span>V-2 in positive pregnant women.
