Hypertrophic cardiomyopathy(HCM)is a common genetic cardiovascular disease and appears in all ethnic groups.HCM is diagnosed on the basis of left ventricular hypertrophy.Echocardiography is a key technique in the diag...Hypertrophic cardiomyopathy(HCM)is a common genetic cardiovascular disease and appears in all ethnic groups.HCM is diagnosed on the basis of left ventricular hypertrophy.Echocardiography is a key technique in the diagnosis of HCM,the prognosis of patients with HCM,the management strategy for HCM,and the follow-up of patients with HCM.This review briefly describes and discusses the practical use of established echocardiography techniques and the current and emerging echocardiographic methods that can help physicians in the correct diagnostic and pathophysiological assessment of patients with HCM.展开更多
Based on engineering practices of four typical traffic immersed tunnels built in China,this paper details the features of the four dominant foundation treatment methods for immersed tunnel construction:pile foundation...Based on engineering practices of four typical traffic immersed tunnels built in China,this paper details the features of the four dominant foundation treatment methods for immersed tunnel construction:pile foundation,sand flow foundation,grouting foundation,and gravel bedding foundation.Subsoil stress time-history of different method are specified first,plus a summary of settlement assessment method for foundation quality control.Further,a comprehensive comparison of settlement and cost of these four foundation treatment methods is conducted to highlights the specific merits,disadvantages and conditions encountered in each foundation treatment method,based on real projects information.The findings of this article could henceforth be applied to foundation treatment work in immersed tube tunnel construction.展开更多
With the shield tunnel going deeper and deeper, the circumferential axial force becomes the governing factor rather than the bending moment. The hand hole acts as a weak point and initial damage in the segment joint e...With the shield tunnel going deeper and deeper, the circumferential axial force becomes the governing factor rather than the bending moment. The hand hole acts as a weak point and initial damage in the segment joint especially when the circumferential axial force is extremely high. Despite the wide application of steel fiber or synthetic fiber in t|ie tunneling, limited researches focus on the structural responses of segment joint with macro structural synthetic fiber (MSSF). In this paper, a 1:2 reduced-scale experiment was conducted to study the structural perfonnance of the segment joint with different types of hand holes under ultra-high axial force. Special attention is paid to failure mode and structural performance (bearing capacity, deformation, cracking, and toughness). Moreover, segment joints with MSSF are also tested to evaluate the effects of MSSF on the failure mode and structural performance of the segment joints. The experiment results show that the hand hole becomes the weakest point of the segment joint under ultra-high axial force. A\/-type crack pattern is always observed before the final failure of the segment joints. Different types and sizes of the hand hole have different degree of influences on the structural behavior of segment joints. The segment joint with MSSF shows higher ultimate bearing capacity and toughness compared to segment joint with common concrete. Besides, the MSSF improves the initial cracking load and anti-spallling resistance of the segment joint.展开更多
文摘Hypertrophic cardiomyopathy(HCM)is a common genetic cardiovascular disease and appears in all ethnic groups.HCM is diagnosed on the basis of left ventricular hypertrophy.Echocardiography is a key technique in the diagnosis of HCM,the prognosis of patients with HCM,the management strategy for HCM,and the follow-up of patients with HCM.This review briefly describes and discusses the practical use of established echocardiography techniques and the current and emerging echocardiographic methods that can help physicians in the correct diagnostic and pathophysiological assessment of patients with HCM.
基金funded by the China National Basic Research Program(973 Program:2015CB057804).
文摘Based on engineering practices of four typical traffic immersed tunnels built in China,this paper details the features of the four dominant foundation treatment methods for immersed tunnel construction:pile foundation,sand flow foundation,grouting foundation,and gravel bedding foundation.Subsoil stress time-history of different method are specified first,plus a summary of settlement assessment method for foundation quality control.Further,a comprehensive comparison of settlement and cost of these four foundation treatment methods is conducted to highlights the specific merits,disadvantages and conditions encountered in each foundation treatment method,based on real projects information.The findings of this article could henceforth be applied to foundation treatment work in immersed tube tunnel construction.
文摘With the shield tunnel going deeper and deeper, the circumferential axial force becomes the governing factor rather than the bending moment. The hand hole acts as a weak point and initial damage in the segment joint especially when the circumferential axial force is extremely high. Despite the wide application of steel fiber or synthetic fiber in t|ie tunneling, limited researches focus on the structural responses of segment joint with macro structural synthetic fiber (MSSF). In this paper, a 1:2 reduced-scale experiment was conducted to study the structural perfonnance of the segment joint with different types of hand holes under ultra-high axial force. Special attention is paid to failure mode and structural performance (bearing capacity, deformation, cracking, and toughness). Moreover, segment joints with MSSF are also tested to evaluate the effects of MSSF on the failure mode and structural performance of the segment joints. The experiment results show that the hand hole becomes the weakest point of the segment joint under ultra-high axial force. A\/-type crack pattern is always observed before the final failure of the segment joints. Different types and sizes of the hand hole have different degree of influences on the structural behavior of segment joints. The segment joint with MSSF shows higher ultimate bearing capacity and toughness compared to segment joint with common concrete. Besides, the MSSF improves the initial cracking load and anti-spallling resistance of the segment joint.