Mg-6Zn-2X(Fe/Cu/Ni)alloys were prepared through semi-continuous casting,with the aim of identifying a degradable magnesium(Mg)alloy suitable for use in fracturing balls.A comparative analysis was conducted to assess t...Mg-6Zn-2X(Fe/Cu/Ni)alloys were prepared through semi-continuous casting,with the aim of identifying a degradable magnesium(Mg)alloy suitable for use in fracturing balls.A comparative analysis was conducted to assess the impacts of adding Cu and Ni,which result in finer grains and the formation of galvanic corrosion sites.Scanner electronic microscopy examination revealed that precipitated phases concentrated at grain boundaries,forming a semi-continuous network structure that facilitated corrosion penetration in Mg-6Zn-2Cu and Mg-6Zn-2Ni alloys.Pitting corrosion was observed in Mg-6Zn-2Fe,while galvanic corrosion was identified as the primary mechanism in Mg-6Zn-2Cu and Mg-6Zn-2Ni alloys.Among the tests,the Mg-6Zn-2Ni alloy exhibited the highest corrosion rate(approximately 932.9 mm/a)due to its significant potential difference.Mechanical testing showed that Mg-6Zn-2Ni alloy possessed suitable ultimate compressive strength,making it a potential candidate material for degradable fracturing balls,effectively addressing the challenges of balancing strength and degradation rate in fracturing applications.展开更多
Efficient synthesis of transition metal hydroxides on conductive substrate is essential for enhancing their merits in industrialization of energy storage field.However,most of the synthetic routes at present mainly re...Efficient synthesis of transition metal hydroxides on conductive substrate is essential for enhancing their merits in industrialization of energy storage field.However,most of the synthetic routes at present mainly rely on traditional bottom-up method,which involves tedious steps,time-consuming treatments,or additional alkaline media,and is unfavorable for high-efficiency production.Herein,we present a facile,ultrafast and general avenue to synthesize transition metal hydroxides on carbon substrate within 13 s by Joule-heating method.With high reaction kinetics caused by the instantaneous high temperature,seven kinds of transition metal-layered hydroxides(TM-LDHs)are formed on carbon cloth.Therein,the fastest synthesis rate reaches~0.46 cm^(2)s^(-1).Density functional theory calculations further demonstrate the nucleation energy barriers and potential mechanism for the formation of metal-based hydroxides on carbon substrates.This efficient approach avoids the use of extra agents,multiple steps,and long production time and endows the LDHs@carbon cloth with outstanding flexibility and machinability,showing practical advantages in both common and micro-zinc ion-based energy storage devices.To prove its utility,as a cathode in rechargeable aqueous alkaline Zn(micro-)battery,the NiCo LDH@carbon cloth exhibits a high energy density,superior to most transition metal LDH materials reported so far.展开更多
The development of potential transition-metal carbide/nitride heterojunctions is hindered by overall understanding and precise modulation for heterointerface effects.Herein,we demonstrate that Mo_(2)C/Mo_(2)N heteroju...The development of potential transition-metal carbide/nitride heterojunctions is hindered by overall understanding and precise modulation for heterointerface effects.Herein,we demonstrate that Mo_(2)C/Mo_(2)N heterojunction with the precisely regulated high-quality interface can achieve marvelous rate performance and energy output via enlarging the interface-effect range and maximizing "accelerated charge" amount The heterointerface mechanism improving properties is synergistically revealed from kinetics and thermodynamics perspectives.Kinetics analysis confirms that the self-built electric field affords a robust force to drive rapid interface electrons/ions migration.The small adsorption energy,high density of states and quite low diffusion barrier thermodynamically enhance the electrochemical reaction dynamics on heterointerface.Consequently,the almost optimal performance of ultrahigh capacitance retention(85.6% even at 10 A g^(-1)) and pronounced energy output(96.4 Wh kg^(-1))in hybridsupercapacitors than other Mo_(2)C/Mo_(2)N-based materials is presented.This work gives new insight into the energy storage mechanism of heterojunction and guides the design of advanced electrodes.展开更多
The tectonic setting of the northern Alxa region during the Late Paleozoic is highly controversial.The key to resolve this controversy is to recognize the Late Paleozoic magmatic processes in the northern Alxa.In this...The tectonic setting of the northern Alxa region during the Late Paleozoic is highly controversial.The key to resolve this controversy is to recognize the Late Paleozoic magmatic processes in the northern Alxa.In this paper,we present new zircon U-Pb ages,Hf-isotopic compositions and whole-rock geochemical data of four granitoids along the Zhusileng-Hangwula Tectonic Belt in the northern Alxa region that could provide critical information about the tectonic evolution of this region.The zircon U-Pb data could be grouped as two phases:Late Devonian granite and diorite(ca.373-360 Ma),and Late Carboniferous granodiorite(ca.318 Ma).The Late Devonian granites and diorites are metaluminous to slightly peraluminous,with A/CNK and A/NK ratios of 0.90-1.11 and0.95-2.19,respectively.The Late Devonian diorites are characterized by high MgO,Cr and Ni contents and MgO#values,together with variableεHf(t)values from-1.0 to+1.3 and old TDM2 ages varied from 1283 Ma to 1426 Ma,indicating the primary magma was potentially derived from magma mixing of depleted mantle with Mesoproterozoic continental crust.Even though the Late Devonian granites yielded most positive and minor negative eHf(t)values between-1.1 to+5.7(three grains are negative)with two-stage model ages(TDM2)of 1003-1438 Ma,they display low MgO,Cr and Ni contents and MgO#values,suggesting that they were mainly derived from juvenile crustal materials,mixed with a small amount of ancient crust.The Late Carboniferous granitoids are metaluminous and medium-K calc-alkaline series,with A/CNK and A/NK ratios ranging from 0.88 to 0.95 and1.75 to 1.90,respectively.These rocks were potentially derived from juvenile crustal materials mixed with depleted mantle,as evidenced by their highεHf(t)values(+11.6 to+14.1)and young TDM2 ages(427 Ma to 586 Ma),as well as high Mg#values,and MgO,Ni and Cr contents.Our data,along with available sedimentary evidence and previous researches,indicate that the Late Devonian and Late Carboniferous rocks are arc-related granitoids under the subduction setting.The identification of arc-related granitoids in the northern Alxa region not only reveals the Late Paleozoic magmatic process in response to the subduction of Paleo Asian Ocean,but also provide significant constrains to the tectonic evolution of the Central Asian Orogenic Belt.展开更多
In a recent paper(Luo H et al.,2022),we found that the peak amplitudes of diurnal magnetic variations,measured during martian days(sols)at the InSight landing site,exhibited quasi Carrington-Rotation(qCR)periods at hi...In a recent paper(Luo H et al.,2022),we found that the peak amplitudes of diurnal magnetic variations,measured during martian days(sols)at the InSight landing site,exhibited quasi Carrington-Rotation(qCR)periods at higher eigenmodes of the natural orthogonal components(NOC);these results were based on~664 sols of magnetic field measurements.However,the source of these periodic variations is still unknown.In this paper we introduce the neutral-wind driven ionospheric dynamo current model(e.g.,Lillis et al.,2019)to investigate the source.Four candidates-the draped IMF,electron density/plasma density,the neutral densities,and the electron temperature in the ionosphere with artificial qCR periodicity,are applied in the modeling to find the main factor likely to be causing the observed surface magnetic field variations that exhibit the same qCR periods.Results show that the electron density/plasma density,which controls the total conductivity in the dynamo region,appears to account for the greatest part of the surface qCR variations;its contribution reaches about 67.6%.The draped IMF,the neutral densities,and the electron temperature account,respectively,for only about 12.9%,10.3%,and 9.2%of the variations.Our study implies that the qCR magnetic variations on the Martian surface are due primarily to variations of the dynamo currents caused by the electron density variations.We suggest also that the timevarying fields with the qCR period could be used to probe the Martian interior's electrical conductivity structure to a depth of at least 700 km.展开更多
The preparation of TiO_2 film has been an important research area.In our work,we obtained the TiO_2 film by hydrothermal treating the amorphous film prepared by sol-gel method or the hydrolysis of titanium alkoxide.Th...The preparation of TiO_2 film has been an important research area.In our work,we obtained the TiO_2 film by hydrothermal treating the amorphous film prepared by sol-gel method or the hydrolysis of titanium alkoxide.The influence of temperature and duration time on the film properties was investigated.The photo degradation of methyl orange in aqueous solution of the film was studied.The films were characterized by XRD and Uv-Vis spectroscope.展开更多
Objective:Several studies have demonstrated different benefits for patients whose disease progressed despite previous trastuzumab treatment.Due to limited real-world data,we evaluate the effectiveness of anti-human ep...Objective:Several studies have demonstrated different benefits for patients whose disease progressed despite previous trastuzumab treatment.Due to limited real-world data,we evaluate the effectiveness of anti-human epidermal growth factor receptor 2(HER2)therapy(lapatinib or trastuzumab)plus chemotherapy or chemotherapy alone in patients who were previously treated with trastuzumab-containing regimens and investigate factors associated with effectiveness.And we further show the effectiveness of the two anti-HER2 therapy groups.Methods:A total of 342 HER2-positive metastatic breast cancer(MBC)patients whose disease progressed during prior anti-HER2(trastuzumab)and standard chemotherapy therapy from Department of Breast Oncology,the Fifth Medical Center of Chinese PLA General Hospital,from August 2010 to December 2016 were included.Seventy-eight patients received standard chemotherapy only,148 patients continued to receive trastuzumab and switched to other chemotherapy drugs,and 116 patients received tyrosine-kinase inhibitors(TKIs;lapatinib)and chemotherapy.The main outcome measures were progression-free survival(PFS),overall response rate(ORR),and clinical benefit rate(CBR).Subgroup analyses were conducted to identify patient characteristics associated with the greatest clinical benefit.Results:After a median follow-up of 26.2(range,2.0-56.0)months,PFS significantly improved with anti-HER2 therapy compared with chemotherapy alone:median 6.0 months with lapatinib[95%confidence interval(95%CI),4.53-7.47],4.5 months with trastuzumab(95%CI,3.99-5.01)vs.3.0 months with chemotherapy alone(95%CI,2.42-3.58);stratified hazard ratio(HR)=0.70,95%CI,0.60-0.81;P<0.0001.The ORR values were 33.6%,25.0%and 12.8%,respectively,the CBR values were 60.3%,48.6%and 26.9%,respectively.The effectiveness of lapatinib group and trastuzumab group were further analyzed.In multivariate analysis,lapatinib group was associated with a longer PFS,after controlling other potential confounders(HR=0.68,95%CI,0.52-0.90;P=0.006).Conclusions:The combination of TKIs and chemotherapy was effective in this cohort previously treated with trastuzumab treatment.Therefore,TKIs combined with chemotherapy is an option for Chinese HER2-positive MBC patients previously treated with trastuzumab treatment.展开更多
Nano-sized titania powders have been prepared by hydrolysis of tetrabutyl titanate in the droplet of water/OP-7/pentanol/cyclohexane microemulsion system.The effects of ingredient change on the water drop size and par...Nano-sized titania powders have been prepared by hydrolysis of tetrabutyl titanate in the droplet of water/OP-7/pentanol/cyclohexane microemulsion system.The effects of ingredient change on the water drop size and particle size were investigated.The prepared TiO_2 was in the form of anatase after annealing.TiO_2 was characterized by TG-TGA, FTIR,XRD to measure the transformation temperature,surface adsorption and average size.展开更多
Pure titanium dioxide (TiO2) particle materials were prepared by hydrolyzing titanium tetrachloride (TiCl4). The microstructures of these materials were determined by X-ray diffraction (XRD), accelerated surface...Pure titanium dioxide (TiO2) particle materials were prepared by hydrolyzing titanium tetrachloride (TiCl4). The microstructures of these materials were determined by X-ray diffraction (XRD), accelerated surface area and porosimetry apparatus (BET), and transmission electron microscopy (TEM). The TiO2 materials obtained by calcinations under different temperatures distinctly revealed different microstructures in crystal structure type, surface area, pore size, pore volume and grain size. The relationship between the microstructure of the TiO2 materials and their electrorheological (ER) activity was investigated. Anatase titania particles have better ER performance than rutile titania particles. Amorphous TiO2 materials display higher ER activity than the crystalline titania materials. A large pore volume can be more advantageous in improving the ER effect of a particle material.展开更多
The study aimed to demonstrate the feasibility of an extradural nerve anastomosis technique for the restoration of a C5 and C6 avulsion of the brachial plexus.Nine fresh frozen human cadavers were used.The diameters,s...The study aimed to demonstrate the feasibility of an extradural nerve anastomosis technique for the restoration of a C5 and C6 avulsion of the brachial plexus.Nine fresh frozen human cadavers were used.The diameters,sizes,and locations of the extradural spinal nerve roots were observed.The lengths of the extradural spinal nerve roots and the distance between the neighboring nerve root outlets were measured and compared in the cervical segments.In the spinal canal,the ventral and dorsal roots were separated by the dura and arachnoid.The ventral and dorsal roots of C7 had sufficient lengths to anastomose those of C6.The ventral and dorsal of C4 had enough length to be transferred to those of C5,respectively.The feasibility of this extradural nerve anastomosis technique for restoring C5 and C6 avulsion of the brachial plexus in human cadavers was demonstrated in our anatomical study.展开更多
Low temperature direct synthesis (LTDS) involves the preparation of a base solution of Sr^(2+),and the mixing of base solution with tetrabutyl titanate solution.LTDS is an advantageous method because it does not requi...Low temperature direct synthesis (LTDS) involves the preparation of a base solution of Sr^(2+),and the mixing of base solution with tetrabutyl titanate solution.LTDS is an advantageous method because it does not require the complex hydrothermal facilities and it can prevent the agglomeration in calcinations of other liquid methods.In our work,we adopted LTDS method to prepare the nano strontium titanate powders,and characterize them by XRD,FT-IR and TGA.The influences of preparation temperature and solvents on grain size and lattice parameters were investigated.The results show that preparation temperature can slightly change the lattice parameters of grain,while solvents also play important roles in the preparation.展开更多
In order to ensure food security, the selection of pesticide must take into account the controlling effect and economy in the chemical control of food crop diseases and pests. Although China has registered a large num...In order to ensure food security, the selection of pesticide must take into account the controlling effect and economy in the chemical control of food crop diseases and pests. Although China has registered a large number of pesticides and fungicides on food crops, traditional statistical methods cannot treat the complex relationships between crops, pests and diseases, as well as pesticides. To this end, the correspondence analysis was used to mine the data of pesticides being registered after January 1, 2010 for the prevention and control of pests and diseases on wheat, corn, and rice in China, in order to reveal the general rules of pesticide use for the prevention and control of grain crop pests and diseases and to provide scientifically recommended pesticide regimens.(1) Recommended pesticides for wheat diseases and pests: For underground pest control, phoxim, diazinon or clothianidin is recommended;imidacloprid is recommended for aphid control;avermectin is recommended for mite control;chlorpyrifos is recommended for midge control;the pesticides for rust control could be selected according to the order of epoxiconazole>flutriafol>kresoxim-methyl>cyproconazole≈hexaconazole;tebuconazole is recommended for the prevention and control of smut;difenoconazole is recommended for the simultaneous occurrence of take-all, smut and sheath blight;it is recommended to use carbendazim or thiophanate-methyl for the control of scab;and triazolone or pyraclostrobin is recommended for the control of powdery mildew.(2) Recommended pesticides for corn diseases and pests: For the control of underground pests, fipronil, carbosulfan or chlorpyrifos are recommended;thiamethoxam is recommended for control of planthoppers and corn aphids;Bacillus thuringiensis or phoxim is recommended for control of corn borers;pyraclostrobin is recommended for the control of northern leaf blight;tebuconazole is recommended for the control of head smut;and fludioxonil+metalaxyl-M is recommended for the control of corn stalk rot.(3) Recommended pesticides for rice diseases and pests: It is recommended to use triazophos, avermectin analogs or methoxyfenozide for the control of borers;for rice planthoppers, the pesticides could be selected in order of pymetrozine>imidacloprid>thiamethoxam>thiazide>nitenpyram;avermectin analogs are recommended for the control of rice leaf rollers;tebuconazole is recommended for the control of rice false smut;prochloraz and its manganese salts are recommended for the control of bakanae disease;hymexazol is recommended for the control of wilt disease;thifluzamide or hexaconazole is recommended for the control of sheath blight;and the pesticides for the control of rice blast are in order of tricyclazole>kasugamycin>fenoxanil>isoprothiolane>Bacillus subtilis. In addition, potential applications of correspondence analysis in other fields of plant protection are discussed.展开更多
With the high-speed development of the Internet,a growing number of Internet users like giving their subjective comments in the BBS,blog and shopping website.These comments contains critics’attitudes,emotions,views a...With the high-speed development of the Internet,a growing number of Internet users like giving their subjective comments in the BBS,blog and shopping website.These comments contains critics’attitudes,emotions,views and other information.Using these information reasonablely can help understand the social public opinion and make a timely response and help dealer to improve quality and service of products and make consumers know merchandise.This paper mainly discusses using convolutional neural network(CNN)for the operation of the text feature extraction.The concrete realization are discussed.Then combining with other text classifier make class operation.The experiment result shows the effectiveness of the method which is proposed in this paper.展开更多
Main Text In the Research Article“Lipidome Atlas of the Developing Heart Uncovers Dynamic Membrane Lipid Attributes Underlying Cardiac Structural and Metabolic Maturation”[1],there was an error in Fig.2B.The authors...Main Text In the Research Article“Lipidome Atlas of the Developing Heart Uncovers Dynamic Membrane Lipid Attributes Underlying Cardiac Structural and Metabolic Maturation”[1],there was an error in Fig.2B.The authors mistakenly repeated the chord diagram designated for P7 with that from P1.The figure amendment did not affect the in-text discussion of the figure,which was focused on changes between P0 and P21,and did not alter the conclusion.Figure 2B has now been corrected in the PDF and HTML(full text).展开更多
Background:Endocrine therapy(ET)and ET-based regimens are the preferred first-line treatment options for hormone receptor(HR)-positive and human epidermal growth factor receptor 2(HER2)-negative metastatic breast canc...Background:Endocrine therapy(ET)and ET-based regimens are the preferred first-line treatment options for hormone receptor(HR)-positive and human epidermal growth factor receptor 2(HER2)-negative metastatic breast cancer(HR+/HER2-MBC),while chemotherapy(CT)is commonly used in clinical practice.The aim of this study was to investigate the efficacy and clinical outcome of ET and CT as first-line treatment in Chinese patients with HR+/HER2-MBC.Methods:Patients diagnosed with HR+/HER2-MBC between January 1st,1996 and September 30th,2018 were screened from the Chinese Society of Clinical Oncology Breast Cancer database.The initial and maintenance first-line treatment,progression-free survival(PFS),and overall survival(OS)were analyzed.Results:Among the 1877 included patients,1215(64.7%)received CT and 662(35.3%)received ET as initial first-line treatment.There were no statistically significant differences in PFS and OS between patients receiving ET and CT as initial first-line treatment in the total population(PFS:12.0 vs.11.0 months,P=0.22;OS:54.0 vs.49.0 months,P=0.09)and propensity score matched population.For patients without disease progression after at least 3 months of initial therapy,maintenance ET following initial CT(CT-ET cohort,n=449)and continuous schedule of ET(ET cohort,n=527)had longer PFS than continuous schedule of CT(CT cohort,n=406)in the total population(CT-ET cohort vs.CT cohort:17.0 vs.8.5 months;P<0.01;ET cohort vs.CT cohort:14.0 vs.8.5 months;P<0.01)and propensity score matched population.OS in the three cohorts yielded the same results as PFS.Conclusions:ET was associated with similar clinical outcome to CT as initial first-line treatment.For patients without disease progression after initial CT,switching to maintenance ET showed superiority in clinical outcome over continuous schedule of CT.展开更多
Mesozoic intracontinental orogeny and deformation were widespread within the southern Central Asian Orogenic Belt(CAOB). Chronological constraints remain unclear when assessing the Mesozoic evolution of the central se...Mesozoic intracontinental orogeny and deformation were widespread within the southern Central Asian Orogenic Belt(CAOB). Chronological constraints remain unclear when assessing the Mesozoic evolution of the central segment of this region. The tectonic belt of Shalazha Mountain located in the center of this region is an ideal place to decode the deformation process. Apatite fission-track(AFT) thermochronology in Shalazha Mountain is applied to constrain the Mesozoic tectonothermal evolution of the central segment of southern CAOB. The bedrock AFT ages range from 161.8 ± 6.9 to 137.0 ± 7.3 Ma, and the first reported detrital AFT obtained from Lower Cretaceous strata shows three age peaks: P1(ca. 178 Ma), P2(ca. 149 Ma) and P3(ca. 105.6 Ma). Bedrock thermal history modeling indicates that Shalazha Mountain have experienced three stages of differential cooling: Late Triassic–Early Jurassic(~230–174 Ma), Late Jurassic–Earliest Cretaceous(~174–135 Ma) and later(~135 Ma). The first two cooling stages are well preserved by the detrital AFT thermochronological result(P1, P2) from the adjacent Lower Cretaceous strata, while P3(ca. 105.6 Ma) records coeval volcanic activity. Furthermore, our data uncover that hanging wall samples cooled faster between the Late Triassic and the Early Cretaceous than those from the footwall of Shalazha thrust fault, which synchronizes with the cooling of the Shalazha Mountain and implies significant two-stage thrust fault activation between ca. 230 and 135 Ma. These new low-temperature thermochronological results from the Shalazha Mountain region and nearby reveal three main phases of differential tectonothermal events representing the Mesozoic reactivation of the central segment of the southern CAOB. In our interpretations, the initial rapid uplift in the Late Triassic was possibly associated with intracontinental orogenesis of the CAOB. Subsequent Middle Jurassic–Earliest Cretaceous cooling is highly consistent with the Mesozoic intense intraplate compression that occurred in the southern CAOB, and is interpreted as a record of closure of the Mongol-Okhotsk Ocean. Then widespread Cretaceous denudation and burial in the adjacent fault basin could be linked with the oblique subduction of the Izanagi Plate along the eastern Eurasian Plate, creating a northeast-trending normal fault and synchronous extension. However, our AFT thermochronometry detects no intense Cenozoic reactivation information of Shalazha Mountain region.展开更多
基金financially supported by the Key Scientific Research Project in Shanxi Province,China(No.202102050201003)the National Natural Science Foundation of China(No.52071227)+2 种基金the Natural Science Foundation of Shanxi Province,China(No.202103021223293)the Central Guiding Science and Technology Development of Local Fund,China(No.YDZJSK20231A046)the Postgraduate Education Innovation Project of Shanxi Province,China(No.2023Y686)。
文摘Mg-6Zn-2X(Fe/Cu/Ni)alloys were prepared through semi-continuous casting,with the aim of identifying a degradable magnesium(Mg)alloy suitable for use in fracturing balls.A comparative analysis was conducted to assess the impacts of adding Cu and Ni,which result in finer grains and the formation of galvanic corrosion sites.Scanner electronic microscopy examination revealed that precipitated phases concentrated at grain boundaries,forming a semi-continuous network structure that facilitated corrosion penetration in Mg-6Zn-2Cu and Mg-6Zn-2Ni alloys.Pitting corrosion was observed in Mg-6Zn-2Fe,while galvanic corrosion was identified as the primary mechanism in Mg-6Zn-2Cu and Mg-6Zn-2Ni alloys.Among the tests,the Mg-6Zn-2Ni alloy exhibited the highest corrosion rate(approximately 932.9 mm/a)due to its significant potential difference.Mechanical testing showed that Mg-6Zn-2Ni alloy possessed suitable ultimate compressive strength,making it a potential candidate material for degradable fracturing balls,effectively addressing the challenges of balancing strength and degradation rate in fracturing applications.
基金the NSFC(22075019)National Key R&D Program of China(2017YFB1104300)。
文摘Efficient synthesis of transition metal hydroxides on conductive substrate is essential for enhancing their merits in industrialization of energy storage field.However,most of the synthetic routes at present mainly rely on traditional bottom-up method,which involves tedious steps,time-consuming treatments,or additional alkaline media,and is unfavorable for high-efficiency production.Herein,we present a facile,ultrafast and general avenue to synthesize transition metal hydroxides on carbon substrate within 13 s by Joule-heating method.With high reaction kinetics caused by the instantaneous high temperature,seven kinds of transition metal-layered hydroxides(TM-LDHs)are formed on carbon cloth.Therein,the fastest synthesis rate reaches~0.46 cm^(2)s^(-1).Density functional theory calculations further demonstrate the nucleation energy barriers and potential mechanism for the formation of metal-based hydroxides on carbon substrates.This efficient approach avoids the use of extra agents,multiple steps,and long production time and endows the LDHs@carbon cloth with outstanding flexibility and machinability,showing practical advantages in both common and micro-zinc ion-based energy storage devices.To prove its utility,as a cathode in rechargeable aqueous alkaline Zn(micro-)battery,the NiCo LDH@carbon cloth exhibits a high energy density,superior to most transition metal LDH materials reported so far.
基金supported by the Beijing Natural Science Founding (2202050)the Beijing Institute of Technology scientific cooperation project (BITBLR2020010)+1 种基金the National Nature Science Foundation of China (21111120074)the National Nature Science Foundation of China (20806008)。
文摘The development of potential transition-metal carbide/nitride heterojunctions is hindered by overall understanding and precise modulation for heterointerface effects.Herein,we demonstrate that Mo_(2)C/Mo_(2)N heterojunction with the precisely regulated high-quality interface can achieve marvelous rate performance and energy output via enlarging the interface-effect range and maximizing "accelerated charge" amount The heterointerface mechanism improving properties is synergistically revealed from kinetics and thermodynamics perspectives.Kinetics analysis confirms that the self-built electric field affords a robust force to drive rapid interface electrons/ions migration.The small adsorption energy,high density of states and quite low diffusion barrier thermodynamically enhance the electrochemical reaction dynamics on heterointerface.Consequently,the almost optimal performance of ultrahigh capacitance retention(85.6% even at 10 A g^(-1)) and pronounced energy output(96.4 Wh kg^(-1))in hybridsupercapacitors than other Mo_(2)C/Mo_(2)N-based materials is presented.This work gives new insight into the energy storage mechanism of heterojunction and guides the design of advanced electrodes.
基金supported by the National Natural Science Foundation of China(21606219)the “Transformational Technologies for Clean Energy and Demonstration”,Strategic Priority Research Program of the Chinese Academy of Sciences(XDA21030900)~~
基金granted by the National Natural Science Foundation of China(Grant Nos.41802119 and 41330315)the Special Projects of China Geological Survey(Grant No.121201011000161111)Doctor’s Fund of Xi’an University of Science and Technology(Grant No.6310117052)。
文摘The tectonic setting of the northern Alxa region during the Late Paleozoic is highly controversial.The key to resolve this controversy is to recognize the Late Paleozoic magmatic processes in the northern Alxa.In this paper,we present new zircon U-Pb ages,Hf-isotopic compositions and whole-rock geochemical data of four granitoids along the Zhusileng-Hangwula Tectonic Belt in the northern Alxa region that could provide critical information about the tectonic evolution of this region.The zircon U-Pb data could be grouped as two phases:Late Devonian granite and diorite(ca.373-360 Ma),and Late Carboniferous granodiorite(ca.318 Ma).The Late Devonian granites and diorites are metaluminous to slightly peraluminous,with A/CNK and A/NK ratios of 0.90-1.11 and0.95-2.19,respectively.The Late Devonian diorites are characterized by high MgO,Cr and Ni contents and MgO#values,together with variableεHf(t)values from-1.0 to+1.3 and old TDM2 ages varied from 1283 Ma to 1426 Ma,indicating the primary magma was potentially derived from magma mixing of depleted mantle with Mesoproterozoic continental crust.Even though the Late Devonian granites yielded most positive and minor negative eHf(t)values between-1.1 to+5.7(three grains are negative)with two-stage model ages(TDM2)of 1003-1438 Ma,they display low MgO,Cr and Ni contents and MgO#values,suggesting that they were mainly derived from juvenile crustal materials,mixed with a small amount of ancient crust.The Late Carboniferous granitoids are metaluminous and medium-K calc-alkaline series,with A/CNK and A/NK ratios ranging from 0.88 to 0.95 and1.75 to 1.90,respectively.These rocks were potentially derived from juvenile crustal materials mixed with depleted mantle,as evidenced by their highεHf(t)values(+11.6 to+14.1)and young TDM2 ages(427 Ma to 586 Ma),as well as high Mg#values,and MgO,Ni and Cr contents.Our data,along with available sedimentary evidence and previous researches,indicate that the Late Devonian and Late Carboniferous rocks are arc-related granitoids under the subduction setting.The identification of arc-related granitoids in the northern Alxa region not only reveals the Late Paleozoic magmatic process in response to the subduction of Paleo Asian Ocean,but also provide significant constrains to the tectonic evolution of the Central Asian Orogenic Belt.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDB41010304)the National Key R&D Program of China (Grant No.2018YFC1503806)the National Natural Science Foundation of China (41874080, 41674168, 41874197)
文摘In a recent paper(Luo H et al.,2022),we found that the peak amplitudes of diurnal magnetic variations,measured during martian days(sols)at the InSight landing site,exhibited quasi Carrington-Rotation(qCR)periods at higher eigenmodes of the natural orthogonal components(NOC);these results were based on~664 sols of magnetic field measurements.However,the source of these periodic variations is still unknown.In this paper we introduce the neutral-wind driven ionospheric dynamo current model(e.g.,Lillis et al.,2019)to investigate the source.Four candidates-the draped IMF,electron density/plasma density,the neutral densities,and the electron temperature in the ionosphere with artificial qCR periodicity,are applied in the modeling to find the main factor likely to be causing the observed surface magnetic field variations that exhibit the same qCR periods.Results show that the electron density/plasma density,which controls the total conductivity in the dynamo region,appears to account for the greatest part of the surface qCR variations;its contribution reaches about 67.6%.The draped IMF,the neutral densities,and the electron temperature account,respectively,for only about 12.9%,10.3%,and 9.2%of the variations.Our study implies that the qCR magnetic variations on the Martian surface are due primarily to variations of the dynamo currents caused by the electron density variations.We suggest also that the timevarying fields with the qCR period could be used to probe the Martian interior's electrical conductivity structure to a depth of at least 700 km.
文摘The preparation of TiO_2 film has been an important research area.In our work,we obtained the TiO_2 film by hydrothermal treating the amorphous film prepared by sol-gel method or the hydrolysis of titanium alkoxide.The influence of temperature and duration time on the film properties was investigated.The photo degradation of methyl orange in aqueous solution of the film was studied.The films were characterized by XRD and Uv-Vis spectroscope.
基金Capital Clinical Medicine Special Project(No.Z181100001718215)National Natural Science Foundation of China(No.81602314).Research number:CSCO-BC RWS 16002。
文摘Objective:Several studies have demonstrated different benefits for patients whose disease progressed despite previous trastuzumab treatment.Due to limited real-world data,we evaluate the effectiveness of anti-human epidermal growth factor receptor 2(HER2)therapy(lapatinib or trastuzumab)plus chemotherapy or chemotherapy alone in patients who were previously treated with trastuzumab-containing regimens and investigate factors associated with effectiveness.And we further show the effectiveness of the two anti-HER2 therapy groups.Methods:A total of 342 HER2-positive metastatic breast cancer(MBC)patients whose disease progressed during prior anti-HER2(trastuzumab)and standard chemotherapy therapy from Department of Breast Oncology,the Fifth Medical Center of Chinese PLA General Hospital,from August 2010 to December 2016 were included.Seventy-eight patients received standard chemotherapy only,148 patients continued to receive trastuzumab and switched to other chemotherapy drugs,and 116 patients received tyrosine-kinase inhibitors(TKIs;lapatinib)and chemotherapy.The main outcome measures were progression-free survival(PFS),overall response rate(ORR),and clinical benefit rate(CBR).Subgroup analyses were conducted to identify patient characteristics associated with the greatest clinical benefit.Results:After a median follow-up of 26.2(range,2.0-56.0)months,PFS significantly improved with anti-HER2 therapy compared with chemotherapy alone:median 6.0 months with lapatinib[95%confidence interval(95%CI),4.53-7.47],4.5 months with trastuzumab(95%CI,3.99-5.01)vs.3.0 months with chemotherapy alone(95%CI,2.42-3.58);stratified hazard ratio(HR)=0.70,95%CI,0.60-0.81;P<0.0001.The ORR values were 33.6%,25.0%and 12.8%,respectively,the CBR values were 60.3%,48.6%and 26.9%,respectively.The effectiveness of lapatinib group and trastuzumab group were further analyzed.In multivariate analysis,lapatinib group was associated with a longer PFS,after controlling other potential confounders(HR=0.68,95%CI,0.52-0.90;P=0.006).Conclusions:The combination of TKIs and chemotherapy was effective in this cohort previously treated with trastuzumab treatment.Therefore,TKIs combined with chemotherapy is an option for Chinese HER2-positive MBC patients previously treated with trastuzumab treatment.
文摘Nano-sized titania powders have been prepared by hydrolysis of tetrabutyl titanate in the droplet of water/OP-7/pentanol/cyclohexane microemulsion system.The effects of ingredient change on the water drop size and particle size were investigated.The prepared TiO_2 was in the form of anatase after annealing.TiO_2 was characterized by TG-TGA, FTIR,XRD to measure the transformation temperature,surface adsorption and average size.
基金This project was supported by the State Key Laboratory of Vehicle Transmission(No. 51457030103 JW0201) the National Natural Science Foundation of China(Grant Nos. 20023005 and 29831010)the National Key Project for Fundamental Researh (G1998061305).
文摘Pure titanium dioxide (TiO2) particle materials were prepared by hydrolyzing titanium tetrachloride (TiCl4). The microstructures of these materials were determined by X-ray diffraction (XRD), accelerated surface area and porosimetry apparatus (BET), and transmission electron microscopy (TEM). The TiO2 materials obtained by calcinations under different temperatures distinctly revealed different microstructures in crystal structure type, surface area, pore size, pore volume and grain size. The relationship between the microstructure of the TiO2 materials and their electrorheological (ER) activity was investigated. Anatase titania particles have better ER performance than rutile titania particles. Amorphous TiO2 materials display higher ER activity than the crystalline titania materials. A large pore volume can be more advantageous in improving the ER effect of a particle material.
基金supported by the National NaturalScience Foundation of China(Grant#81401791,#81371968,#81672152)A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘The study aimed to demonstrate the feasibility of an extradural nerve anastomosis technique for the restoration of a C5 and C6 avulsion of the brachial plexus.Nine fresh frozen human cadavers were used.The diameters,sizes,and locations of the extradural spinal nerve roots were observed.The lengths of the extradural spinal nerve roots and the distance between the neighboring nerve root outlets were measured and compared in the cervical segments.In the spinal canal,the ventral and dorsal roots were separated by the dura and arachnoid.The ventral and dorsal roots of C7 had sufficient lengths to anastomose those of C6.The ventral and dorsal of C4 had enough length to be transferred to those of C5,respectively.The feasibility of this extradural nerve anastomosis technique for restoring C5 and C6 avulsion of the brachial plexus in human cadavers was demonstrated in our anatomical study.
基金support from Jiangxi Education Science FoundationNanchang University Science Foundation.
文摘Low temperature direct synthesis (LTDS) involves the preparation of a base solution of Sr^(2+),and the mixing of base solution with tetrabutyl titanate solution.LTDS is an advantageous method because it does not require the complex hydrothermal facilities and it can prevent the agglomeration in calcinations of other liquid methods.In our work,we adopted LTDS method to prepare the nano strontium titanate powders,and characterize them by XRD,FT-IR and TGA.The influences of preparation temperature and solvents on grain size and lattice parameters were investigated.The results show that preparation temperature can slightly change the lattice parameters of grain,while solvents also play important roles in the preparation.
基金Supported by National Science and Technology Innovation Project for High Grain Yield and EfficiencyIntegration and Demonstration of Maize Disaster Reduction and Quality and Efficiency Improvement in Rain-fed Areas of Southern Henan (2018YFD0300706)。
文摘In order to ensure food security, the selection of pesticide must take into account the controlling effect and economy in the chemical control of food crop diseases and pests. Although China has registered a large number of pesticides and fungicides on food crops, traditional statistical methods cannot treat the complex relationships between crops, pests and diseases, as well as pesticides. To this end, the correspondence analysis was used to mine the data of pesticides being registered after January 1, 2010 for the prevention and control of pests and diseases on wheat, corn, and rice in China, in order to reveal the general rules of pesticide use for the prevention and control of grain crop pests and diseases and to provide scientifically recommended pesticide regimens.(1) Recommended pesticides for wheat diseases and pests: For underground pest control, phoxim, diazinon or clothianidin is recommended;imidacloprid is recommended for aphid control;avermectin is recommended for mite control;chlorpyrifos is recommended for midge control;the pesticides for rust control could be selected according to the order of epoxiconazole>flutriafol>kresoxim-methyl>cyproconazole≈hexaconazole;tebuconazole is recommended for the prevention and control of smut;difenoconazole is recommended for the simultaneous occurrence of take-all, smut and sheath blight;it is recommended to use carbendazim or thiophanate-methyl for the control of scab;and triazolone or pyraclostrobin is recommended for the control of powdery mildew.(2) Recommended pesticides for corn diseases and pests: For the control of underground pests, fipronil, carbosulfan or chlorpyrifos are recommended;thiamethoxam is recommended for control of planthoppers and corn aphids;Bacillus thuringiensis or phoxim is recommended for control of corn borers;pyraclostrobin is recommended for the control of northern leaf blight;tebuconazole is recommended for the control of head smut;and fludioxonil+metalaxyl-M is recommended for the control of corn stalk rot.(3) Recommended pesticides for rice diseases and pests: It is recommended to use triazophos, avermectin analogs or methoxyfenozide for the control of borers;for rice planthoppers, the pesticides could be selected in order of pymetrozine>imidacloprid>thiamethoxam>thiazide>nitenpyram;avermectin analogs are recommended for the control of rice leaf rollers;tebuconazole is recommended for the control of rice false smut;prochloraz and its manganese salts are recommended for the control of bakanae disease;hymexazol is recommended for the control of wilt disease;thifluzamide or hexaconazole is recommended for the control of sheath blight;and the pesticides for the control of rice blast are in order of tricyclazole>kasugamycin>fenoxanil>isoprothiolane>Bacillus subtilis. In addition, potential applications of correspondence analysis in other fields of plant protection are discussed.
文摘With the high-speed development of the Internet,a growing number of Internet users like giving their subjective comments in the BBS,blog and shopping website.These comments contains critics’attitudes,emotions,views and other information.Using these information reasonablely can help understand the social public opinion and make a timely response and help dealer to improve quality and service of products and make consumers know merchandise.This paper mainly discusses using convolutional neural network(CNN)for the operation of the text feature extraction.The concrete realization are discussed.Then combining with other text classifier make class operation.The experiment result shows the effectiveness of the method which is proposed in this paper.
基金the support from the National Natural Science Foundation of China(NSFC)(U20A20128,52263027,22379060,52173169 and 52222312)the"Double Thousand Plan"Science and Technology Innovation High-end Talent Project of Jiangxi Province(jxsq2019201049)+2 种基金the Natural Science Foundation of Jiangxi Province(20231ZDH04036,20212BAB214055 and 20224ACB204007)China National Postdoctoral Program for Innovative Talents(BX2021117)China Postdoctoral Science Foundation(2021M700060)。
文摘Main Text In the Research Article“Lipidome Atlas of the Developing Heart Uncovers Dynamic Membrane Lipid Attributes Underlying Cardiac Structural and Metabolic Maturation”[1],there was an error in Fig.2B.The authors mistakenly repeated the chord diagram designated for P7 with that from P1.The figure amendment did not affect the in-text discussion of the figure,which was focused on changes between P0 and P21,and did not alter the conclusion.Figure 2B has now been corrected in the PDF and HTML(full text).
基金supported by research and development project of medical data and artificial intelligence in Chinese PLA General Hospital(Grant No.2019MBD-056)
文摘Background:Endocrine therapy(ET)and ET-based regimens are the preferred first-line treatment options for hormone receptor(HR)-positive and human epidermal growth factor receptor 2(HER2)-negative metastatic breast cancer(HR+/HER2-MBC),while chemotherapy(CT)is commonly used in clinical practice.The aim of this study was to investigate the efficacy and clinical outcome of ET and CT as first-line treatment in Chinese patients with HR+/HER2-MBC.Methods:Patients diagnosed with HR+/HER2-MBC between January 1st,1996 and September 30th,2018 were screened from the Chinese Society of Clinical Oncology Breast Cancer database.The initial and maintenance first-line treatment,progression-free survival(PFS),and overall survival(OS)were analyzed.Results:Among the 1877 included patients,1215(64.7%)received CT and 662(35.3%)received ET as initial first-line treatment.There were no statistically significant differences in PFS and OS between patients receiving ET and CT as initial first-line treatment in the total population(PFS:12.0 vs.11.0 months,P=0.22;OS:54.0 vs.49.0 months,P=0.09)and propensity score matched population.For patients without disease progression after at least 3 months of initial therapy,maintenance ET following initial CT(CT-ET cohort,n=449)and continuous schedule of ET(ET cohort,n=527)had longer PFS than continuous schedule of CT(CT cohort,n=406)in the total population(CT-ET cohort vs.CT cohort:17.0 vs.8.5 months;P<0.01;ET cohort vs.CT cohort:14.0 vs.8.5 months;P<0.01)and propensity score matched population.OS in the three cohorts yielded the same results as PFS.Conclusions:ET was associated with similar clinical outcome to CT as initial first-line treatment.For patients without disease progression after initial CT,switching to maintenance ET showed superiority in clinical outcome over continuous schedule of CT.
基金supported by the National Natural Science Foundation of China (No. 41972153)the Geological Survey Project of China Geological Survey (No. DD20160172)the Science and Technology Department of China National Petroleum Corporation (No. 2018A-0104)。
文摘Mesozoic intracontinental orogeny and deformation were widespread within the southern Central Asian Orogenic Belt(CAOB). Chronological constraints remain unclear when assessing the Mesozoic evolution of the central segment of this region. The tectonic belt of Shalazha Mountain located in the center of this region is an ideal place to decode the deformation process. Apatite fission-track(AFT) thermochronology in Shalazha Mountain is applied to constrain the Mesozoic tectonothermal evolution of the central segment of southern CAOB. The bedrock AFT ages range from 161.8 ± 6.9 to 137.0 ± 7.3 Ma, and the first reported detrital AFT obtained from Lower Cretaceous strata shows three age peaks: P1(ca. 178 Ma), P2(ca. 149 Ma) and P3(ca. 105.6 Ma). Bedrock thermal history modeling indicates that Shalazha Mountain have experienced three stages of differential cooling: Late Triassic–Early Jurassic(~230–174 Ma), Late Jurassic–Earliest Cretaceous(~174–135 Ma) and later(~135 Ma). The first two cooling stages are well preserved by the detrital AFT thermochronological result(P1, P2) from the adjacent Lower Cretaceous strata, while P3(ca. 105.6 Ma) records coeval volcanic activity. Furthermore, our data uncover that hanging wall samples cooled faster between the Late Triassic and the Early Cretaceous than those from the footwall of Shalazha thrust fault, which synchronizes with the cooling of the Shalazha Mountain and implies significant two-stage thrust fault activation between ca. 230 and 135 Ma. These new low-temperature thermochronological results from the Shalazha Mountain region and nearby reveal three main phases of differential tectonothermal events representing the Mesozoic reactivation of the central segment of the southern CAOB. In our interpretations, the initial rapid uplift in the Late Triassic was possibly associated with intracontinental orogenesis of the CAOB. Subsequent Middle Jurassic–Earliest Cretaceous cooling is highly consistent with the Mesozoic intense intraplate compression that occurred in the southern CAOB, and is interpreted as a record of closure of the Mongol-Okhotsk Ocean. Then widespread Cretaceous denudation and burial in the adjacent fault basin could be linked with the oblique subduction of the Izanagi Plate along the eastern Eurasian Plate, creating a northeast-trending normal fault and synchronous extension. However, our AFT thermochronometry detects no intense Cenozoic reactivation information of Shalazha Mountain region.