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Crashworthiness Design and Multi-Objective Optimization for Bio-Inspired Hierarchical Thin-Walled Structures 被引量:5
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作者 shaoqiang xu Weiwei Li +2 位作者 Lin Li Tao Li Chicheng Ma 《Computer Modeling in Engineering & Sciences》 SCIE EI 2022年第5期929-947,共19页
Thin-walled structures have been used in many fields due to their superior mechanical properties.In this paper,two types of hierarchical multi-cell tubes,inspired by the self-similarity of Pinus sylvestris,are propose... Thin-walled structures have been used in many fields due to their superior mechanical properties.In this paper,two types of hierarchical multi-cell tubes,inspired by the self-similarity of Pinus sylvestris,are proposed to enhance structural energy absorption performance.The finite element models of the hierarchical structures are established to validate the crashworthiness performance under axial dynamic load.The theoreticalmodel of themean crushing force is also derived based on the simplified super folded element theory.The finite element results demonstrate that the energy absorption characteristics and deformation mode of the bionic hierarchical thin-walled tubes are further improved with the increase of hierarchical sub-structures.It can be also obtained that the energy absorption performance of corner self-similar tubes is better than edge self-similar tubes.Furthermore,multiobjective optimization of the hierarchical tubes is constructed by employing the response surface method and genetic algorithm,and the corresponding Pareto front diagram is obtained.This research provides a new idea for the crashworthiness design of thin-walled structures. 展开更多
关键词 Bionic structure crashworthiness design hierarchical tube multi-objective optimization
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谷胱甘肽在结直肠癌增殖转移及诊疗中的研究进展
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作者 刘成飞 徐少强 +1 位作者 姚添 黄河 《中华结直肠疾病电子杂志》 2022年第6期506-510,共5页
全球范围内,结直肠癌是发病率和死亡率分别高居第三及第二位的恶性肿瘤。谷胱甘肽是生物体内抗氧化系统的重要成分。国内外研究证明谷胱甘肽在结直肠癌组织中水平异常增高,参与了结直肠癌细胞的氧化应激、铁死亡等方面,并具有成为结直... 全球范围内,结直肠癌是发病率和死亡率分别高居第三及第二位的恶性肿瘤。谷胱甘肽是生物体内抗氧化系统的重要成分。国内外研究证明谷胱甘肽在结直肠癌组织中水平异常增高,参与了结直肠癌细胞的氧化应激、铁死亡等方面,并具有成为结直肠癌治疗靶点的潜力。本文主要围绕谷胱甘肽在结直肠癌增殖转移及诊疗中的研究作一综述,阐述其在结直肠癌中的研究现状及应用前景。 展开更多
关键词 结直肠肿瘤 谷胱甘肽 氧化应激 铁死亡
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