行气活血化瘀汤联合康复锻炼治疗腰椎间盘突出症临床研究

目的:观察行气活血化瘀汤联合康复锻炼治疗腰椎间盘突出症(LDH)的临床疗效。方法:选取70例LDH患者,按随机数字表法分为对照组和观察组各35例。对照组给予常规西药治疗,观察组在对照组基础上给予行气活血化瘀汤联合康复锻炼。比较2组临床疗效、中医证候评分、腰椎功能、疼痛程度及炎症反应。结果:观察组总有效率为91.43%,高于对照组68.57%(P<0.05)。治疗后,2组各项中医证候评分较治疗前降低(P<0.05),且观察组各项中医证候评分低于对照组(P<0.05)。治疗后,2组日本骨科协会腰痛评价评价量表(JOA)评分较治疗前升高,Oswestry功能障碍指数(ODI)、视觉模拟量表(VAS)评分较治疗前降低(P<0.05);且观察组JOA评分高于对照组,ODI、VAS评分低于对照组(P<0.05)。治疗后,2组TNF-α、IL-1β水平较治疗前降低(P<0.05);且观察组TNF-α、IL-1β水平低于对照组(P<0.05)。结论:行气活血化瘀汤联合康复锻炼治疗LDH的康复效果显著,可缓解患者临床症状,改善腰椎功能,缓解疼痛感,减轻炎症反应,有利于促进病情康复。

丹鸡活血汤辅助治疗慢性乙型肝炎肝纤维化对患者肝功能及血清炎性反应介质的影响

目的:探讨丹鸡活血汤辅助治疗慢性乙型肝炎肝纤维化对患者肝功能及血清炎性反应介质的影响。方法:选取2015年3月至2017年3月邯郸市传染病医院收治的慢性乙型肝炎肝纤维化患者160例,随机分为观察组与对照组,每组80例。对照组采用常规护肝治疗,观察组在对照组的基础上给予丹鸡活血汤治疗,3个月为1个疗程,2组均连续治疗2个疗程。比较2组治疗前后中医证候积分、肝功能指标、肝纤维化指标及血清炎性反应介质变化。结果:与治疗前比较,治疗后2组肝部不适或疼痛、舌质暗红、面色晦暗、食欲衰退与乏力等主要中医证候积分均显著下降(P<0.05),且观察组显著低于对照组(P<0.05);与治疗前比较,治疗后2组血清丙氨酸转氨酶(ALT)、总胆红素(TBIL)、天门冬氨酸转氨酶(AST)均显著下降(P<0.05),且观察组显著低于对照组(P<0.05);白蛋白(ALB)显著升高(P<0.05),且观察组显著高于对照组(P<0.05);与治疗前比较,治疗后2组血清透明质酸(HA)、层粘连蛋白(LN)、Ⅲ型前胶原肽(PC-Ⅲ)、Ⅳ型胶原(Ⅳ-C)、基质金属蛋白酶-1(MMP-1)、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)及观察组丙二醛(MDA)水平均显著下降(P<0.05),且观察组均显著低于对照组(P<0.05)。结论:丹鸡活血汤辅助治疗慢性乙型肝炎肝纤维化可有效改善患者临床症状,改善其肝功能的同时抑制肝纤维化进展,其作用机制可能与其降低炎性反应介质水平有关。

顶空气相色谱法测定乙醇消毒剂中乙醇含量

采用毛细管顶空气相色谱法测定乙醇消毒剂中的乙醇含量。该方法以体积比配制试液,采用极性岛津WondCapwax毛细管色谱柱分离,FID检测器进行检测,内标法定量。结果表明,乙醇的体积浓度在0.2~1.0m L/L范围内与其色谱峰面积呈良好的线性关系,相关系数为0.9998,方法定量限为1μL/L,加标平均回收率99.8%,该方法简单、快捷、准确。

Effects of Acupoint Massage Combined with Psychological Nursing on Depression and Hope Level and Coping Style in Hospitalized Patients with Hepatocirrhosis

OBJECTIVE: To explore the effects of acupoint massage combined with psychological nursing on depression and hope level and coping style in hospitalized patients with hepatocirrhosis, and to provide scientific basis for clinical treatment. METHODS: A total of 86 patients with hepatocirrhosis hospitalized in The Sixth Hospital of Handan from June 2015 to June 2018 were selected and divided into 2 groups according to the nursing method. The control group, with a total of 42 patients, were given psychological nursing intervention. The observation group, with a total of 44 patients, were given acupoint massage and psychological nursing intervention. Changes in depression levels, hope levels, and coping style scores were compared between the 2 groups. RESULTS: There was no significant difference in depression, hope level and coping style before the intervention between the 2 groups(P > 0.05). In the observation group, the self-rating depression scale(SDS) score of depression before intervention was 55.16 ± 4.17; and the positive attitude score was 8.40 ± 2.02; the positive action score was 8.33 ± 3.05; and the intimate score was 8.13 ± 2.44. The negative response score was 30.14 ± 3.31, and the positive response score was 30.49 ± 3.26. Before the intervention, the SDS score in the control group was 56.81 ± 4.39, and the positive attitude score was 8.29 ± 1.98. The positive action score was 8.04 ± 2.57, and the intimate score was 8.06 ± 2.31. The total level of hope score was 24.07 ± 3.11. The negative coping score was 30.55 ± 3.06, and the positive coping score was 30.93 ± 3.17. After intervention the SDS scores of the observation group were lower than those of the control group(P < 0.05). The SDS score of the observation group was 36.19 ± 4.19, and the SDS score of the control group was 42.95 ± 3.71. The total level of hope in the observation group was higher than that in the control group after intervention(P < 0.05). The positive attitude score of the observation group was 16.10 ± 2.15, and the score of positive action was 14.74 ± 3.11; the score of intimate relationship was 15.08 ± 5.45; and the total score of hope was 45.71 ± 5.63. The positive attitude score of the control group was 10.92 ± 2.07; the score of positive action was 11.38 ± 3.14; the score of intimate relationship was 10.92 ± 2.33; and the total score of hope was 34.09 ± 5.77. The patients in the observation group had lower response scores after intervention than the control group, and the positive response scores were higher than those in the control group(P < 0.05). The negative response score of the observation group was 20.14 ± 2.19; the positive response score was 38.92 ± 4.33; the negative response score of the control group was 26.61 ± 2.34; and the positive response score was 34.08 ± 2.69. CONCLUSION: Acupoint massage combined with psychological nursing can effectively improve depression in hospitalized patients with hepatocirrhosis, improve the patient's hope level, help patients cope with lifestyle changes from negative to positive, which is worthy of clinical promotion.