To the Editor:A 13-year-old girl with Crohn disease(CD)from Shandong Province transferred to our inflammatory bowel disease(IBD)center during April 2013.Three months previously,the patient presented with hematochezia ...To the Editor:A 13-year-old girl with Crohn disease(CD)from Shandong Province transferred to our inflammatory bowel disease(IBD)center during April 2013.Three months previously,the patient presented with hematochezia and fever,but antibiotic treatment was unsuccessful.After admission,a colonoscopy indicated manifestations of segmental lesions,cobble stoning,and stricture[Figure 1 A].Cytomegalovirus,Epstein-Barr virus,Clostridium difficile^and amoebae were excluded as possible causes.There were also no indications of Behcet disease,systemic vasculitis,or other autoimmune diseases.Our initial diagnosis was active severe CD(Vienna typing,A1L3B2).This study was approved by the Ethical Committee of First Hospital of Peking University(No.2019153).An appropriate signed patient consent form was obtained.展开更多
文摘To the Editor:A 13-year-old girl with Crohn disease(CD)from Shandong Province transferred to our inflammatory bowel disease(IBD)center during April 2013.Three months previously,the patient presented with hematochezia and fever,but antibiotic treatment was unsuccessful.After admission,a colonoscopy indicated manifestations of segmental lesions,cobble stoning,and stricture[Figure 1 A].Cytomegalovirus,Epstein-Barr virus,Clostridium difficile^and amoebae were excluded as possible causes.There were also no indications of Behcet disease,systemic vasculitis,or other autoimmune diseases.Our initial diagnosis was active severe CD(Vienna typing,A1L3B2).This study was approved by the Ethical Committee of First Hospital of Peking University(No.2019153).An appropriate signed patient consent form was obtained.