In this study,microstructural brain damage in Parkinson＇s disease patients was examined using diffusion tensor imaging and tract-based spatial statistics.The analyses revealed the presence of neuronal damage in the s...In this study,microstructural brain damage in Parkinson＇s disease patients was examined using diffusion tensor imaging and tract-based spatial statistics.The analyses revealed the presence of neuronal damage in the substantia nigra and putamen in the Parkinson＇s disease patients.Moreover,disease symptoms worsened with increasing damage to the substantia nigra,confirming that the substantia nigra and basal ganglia are the main structures affected in Parkinson＇s disease.We also found that microstructural damage to the putamen,caudate nucleus and frontal lobe positively correlated with depression.Based on the tract-based spatial statistics,various white matter tracts appeared to have microstructural damage,and this correlated with cognitive disorder and depression.Taken together,our results suggest that diffusion tensor imaging and tract-based spatial statistics can be used to effectively study brain function and microstructural changes in patients with Parkinson＇s disease.Our novel findings should contribute to our understanding of the histopathological basis of cognitive dysfunction and depression in Parkinson＇s disease.展开更多
In this study, the degradation efficiencies of zero-valent iron （ZVI） powders with different structures and components wereevaluated for methyl orange （MO）. The results show that the structure is an essential fact...In this study, the degradation efficiencies of zero-valent iron （ZVI） powders with different structures and components wereevaluated for methyl orange （MO）. The results show that the structure is an essential factor that affects degradation, andadded non-metallic elements help optimize the structure. The amorphous and balled-milled crystalline Fe7oSiloB2o hascomparative degradation efficiencies to MO with tl/2 values of 6.9 and 7.0 min, respectively. Increasing the boron contentcan create a favorable structure and promote degradation. The ball-milled crystalline Fe70B30 and Fe43.64B56.36 powdershave relatively short tl/2 values of 5.2 and 3.3 rain, respectively. The excellent properties are mainly attributed to theirheterogeneous structure with boron-doped active sites in ZVI. Composition segregation in the nanoscale range in anamorphous FeSiB alloy and small boron particles in the microscale range embedded in large iron particles prepared by ball-milling, both constitute effective galvanic cells that promote iron electron loss and therefore decompose organic chemicals.These findings may provide a new, highly efficient, low-cost commercial method for azo dye wastewater treatment usingZVI.展开更多
文摘In this study,microstructural brain damage in Parkinson＇s disease patients was examined using diffusion tensor imaging and tract-based spatial statistics.The analyses revealed the presence of neuronal damage in the substantia nigra and putamen in the Parkinson＇s disease patients.Moreover,disease symptoms worsened with increasing damage to the substantia nigra,confirming that the substantia nigra and basal ganglia are the main structures affected in Parkinson＇s disease.We also found that microstructural damage to the putamen,caudate nucleus and frontal lobe positively correlated with depression.Based on the tract-based spatial statistics,various white matter tracts appeared to have microstructural damage,and this correlated with cognitive disorder and depression.Taken together,our results suggest that diffusion tensor imaging and tract-based spatial statistics can be used to effectively study brain function and microstructural changes in patients with Parkinson＇s disease.Our novel findings should contribute to our understanding of the histopathological basis of cognitive dysfunction and depression in Parkinson＇s disease.
基金supported by the Program of Introducing Innovative Research Team in Dongguan under Contract Number 2014607109Shenzhen Science and Technology Research Grants under Contract Numbers JCYJ20160422104921235,JCYJ20160422143659258 and JCYJ20160422144751573
文摘In this study, the degradation efficiencies of zero-valent iron （ZVI） powders with different structures and components wereevaluated for methyl orange （MO）. The results show that the structure is an essential factor that affects degradation, andadded non-metallic elements help optimize the structure. The amorphous and balled-milled crystalline Fe7oSiloB2o hascomparative degradation efficiencies to MO with tl/2 values of 6.9 and 7.0 min, respectively. Increasing the boron contentcan create a favorable structure and promote degradation. The ball-milled crystalline Fe70B30 and Fe43.64B56.36 powdershave relatively short tl/2 values of 5.2 and 3.3 rain, respectively. The excellent properties are mainly attributed to theirheterogeneous structure with boron-doped active sites in ZVI. Composition segregation in the nanoscale range in anamorphous FeSiB alloy and small boron particles in the microscale range embedded in large iron particles prepared by ball-milling, both constitute effective galvanic cells that promote iron electron loss and therefore decompose organic chemicals.These findings may provide a new, highly efficient, low-cost commercial method for azo dye wastewater treatment usingZVI.
