Modulating both the clock frequency and supply voltage of the network-on-chip(No C) during runtime can reduce the power consumption and heat flux, but will lead to the increase of the latency of No C.It is necessary t...Modulating both the clock frequency and supply voltage of the network-on-chip(No C) during runtime can reduce the power consumption and heat flux, but will lead to the increase of the latency of No C.It is necessary to find a tradeoff between power consumption and communication latency. So we propose an analytical latency model which can show us the relationship of them. The proposed model to analyze latency is based on the M/G/1 queuing model, which is suitable for dynamic frequency scaling. The experiment results show that the accuracy of this model is more than 90%.展开更多
Objective:To investigate the influencing factors of chronic hepatitis B with nonalcoholic fatty liver disease,and to provide a reference for screening and clinical treatment of high-risk groups.Methods:A case-control ...Objective:To investigate the influencing factors of chronic hepatitis B with nonalcoholic fatty liver disease,and to provide a reference for screening and clinical treatment of high-risk groups.Methods:A case-control study was conducted.According to the inclusion and exclusion criteria,133 cases of newly diagnosed patients with CHB combined with NAFLD were enrolled in the Affiliated Hospital of North China University of Technology and Tangshan Infectious Disease Hospital from January 2015 to January 2018.139 cases of newly diagnosed patients with CHB diagnosed in the same period were selected as the control group.The clinical data,initial laboratory examination and imaging findings of the two groups of patients were compared to analyze the influencing factors of chronic hepatitis B combined with nonalcoholic fatty liver disease.Results:1 The BMI,ALT,AST,GGT,FBG,TG and CAP in the case group were significantly higher than those in the control group,the difference was statistically significant(P<0.05).The control group HDL-C,HBcAb,type III procollagen amino terminal peptide,The type IV collagen,laminin and LSM were higher than the case group,the difference was statistically significant(P<0.05).The case group was more likely to be associated with complications,and the difference was statistically significant(P=0.01).2 Univariate analysis showed that About the author:Zhang Guoshun,male,chief physician,professor,master's tutor,doctoral,mainly engaged in research and prevention of liver diseases,13930565676,zguoshun@sina.com.Fund Project:China Hepatitis Prevention Foundation Funded Project(No.:TQGB20170015);Hebei Province Medical Science Research Key Project(No.20170933);North China University of Technology Graduate Innovation Project(No.2019S49)patients in the case group had BMI≥25Kg/m2,GGT>45U/L,type IV collagen≤140ng/ml,laminin≤140ng/ml,CAP≥283dB/m,hyperglycemia,high glycerol The proportion of patients with lipemia was significantly higher than that of the control group,the difference was statistically significant(P<0.05);3 binary logistic regression analysis showed that GGT,FBG,BMI,laminin,CAP were predictive of chronic hepatitis B combined with non-An effective indicator of alcoholic fatty liver disease.Conclusion 1GGT,BMI,FBG,laminin and CAP are the influencing factors of CHB combined with NAFLD.The occurrence of 2NAFLD is closely related to obesity,hyperglycemia and hypertriglyceridemia.The HBcAb and liver fibrosis indexes are decreased when CHB combined with NAFLD,and the mechanism is still unclear.展开更多
Objective: To explore the fatal risk factors of liver cirrhosis complicated with the first upper gastrointestinal bleeding, so as to provide reference for clinical prevention and treatment. Methods: 572 patients with ...Objective: To explore the fatal risk factors of liver cirrhosis complicated with the first upper gastrointestinal bleeding, so as to provide reference for clinical prevention and treatment. Methods: 572 patients with cirrhosis admitted to North China University of Science and Technology and Tangshan Infectious Diseases Hospital from January 2014 to January 2018 were selected. According to whether there is concurrent upper gastrointestinal bleeding, it is divided into 163 cases of hemorrhage group and 409 cases of non-bleeding group. The patients in the hemorrhagic group were divided into case group (65 cases died of first upper gastrointestinal bleeding) and control group (98 cases died of non-first upper gastrointestinal bleeding). The general clinical data, laboratory and imaging data of the patients were analyzed. The risk factors of upper gastrointestinal bleeding in cirrhosis and the independent risk factors of the first upper gastrointestinal bleeding in cirrhosis were analyzed. Results: (1) Univariate analysis showed that: there were significant differences in Hb, PLT, CHE, ALB, TBIL, PT, left gastric vein diameter, portal vein diameter, course of cirrhosis, family history of cirrhosis, Child classification of liver function, esophagogastric varices, ascites, hepatic encephalopathy and portal vein thrombosis between hemorrhagic and non-hemorrhagic groups (P<0.05). The difference was statistically significant;(2) Multivariate logistic regression analysis showed that the diameter of left gastric vein, esophageal varices, ascites, Child C grade of liver function and portal vein thrombosis were risk factors for upper gastrointestinal bleeding in patients with cirrhosis. Left gastric vein diameter, esophagogastric varices and portal vein thrombosis are independent risk factors for first upper gastrointestinal bleeding in cirrhosis. Conclusion:Wider internal diameter of left gastric vein, severe esophagogastric varices and portal vein thrombosis are independent risk factors for fatal upper gastrointestinal bleeding in cirrhosis.展开更多
The non-noble metal modified sulfated zirconia was found easy to deactivate.Herein,highly active and highly stable non-noble core-shell Ni-S_(2)O_(8)^(2−)/Al_(2)O_(3)@ZrO_(2) catalysts(Ni-SA@Z-x,x=Al content in wt%)ha...The non-noble metal modified sulfated zirconia was found easy to deactivate.Herein,highly active and highly stable non-noble core-shell Ni-S_(2)O_(8)^(2−)/Al_(2)O_(3)@ZrO_(2) catalysts(Ni-SA@Z-x,x=Al content in wt%)have been successfully prepared and investigated for n-pentane isomerization.The results showed that the core-shell Ni-SA@Z-30 provided a sustained high isopentane yield(63.1%)with little or no deactivation within 5000 min at a mild reaction pressure of 2.0 MPa,which can be attributed to the following factors:(i)carbon deposition was greatly suppressed by the large pore size and huge pore volume;(ii)the loss of sulfur entities was suppressed because the small and highly dispersed tetragonal ZrO_(2) particles can bond with the S species strongly;(iii)strong Brønsted acidity can be maintained well after the isomerization.The pore structures and acid nature of the core-shell Ni-SA@Z-x are entirely different from those of the normal structure Ni-S_(2)O_(8)^(2−)/ZrO_(2)-Al_(2)O_(3),even though the Al content and the compositions of the individual components are the same.The Al_(2)O_(3)cores endow the catalysts with high internal surface area and high mechanical strength.Meanwhile,the ZrO_(2) shell,which consists of more and smaller tetragonal ZrO_(2) particles because of the large surface area of the Al_(2)O_(3)core,promotes the formation of more stable sulfur species and stronger binding sites.展开更多
基金supported by the National Natural Science Foundation of China under Grant No.61376024 and No.61306024Natural Science Foundation of Guangdong Province under Grant No.S2013040014366Basic Research Programme of Shenzhen No.JCYJ20140417113430642 and JCYJ20140901003939020
文摘Modulating both the clock frequency and supply voltage of the network-on-chip(No C) during runtime can reduce the power consumption and heat flux, but will lead to the increase of the latency of No C.It is necessary to find a tradeoff between power consumption and communication latency. So we propose an analytical latency model which can show us the relationship of them. The proposed model to analyze latency is based on the M/G/1 queuing model, which is suitable for dynamic frequency scaling. The experiment results show that the accuracy of this model is more than 90%.
文摘Objective:To investigate the influencing factors of chronic hepatitis B with nonalcoholic fatty liver disease,and to provide a reference for screening and clinical treatment of high-risk groups.Methods:A case-control study was conducted.According to the inclusion and exclusion criteria,133 cases of newly diagnosed patients with CHB combined with NAFLD were enrolled in the Affiliated Hospital of North China University of Technology and Tangshan Infectious Disease Hospital from January 2015 to January 2018.139 cases of newly diagnosed patients with CHB diagnosed in the same period were selected as the control group.The clinical data,initial laboratory examination and imaging findings of the two groups of patients were compared to analyze the influencing factors of chronic hepatitis B combined with nonalcoholic fatty liver disease.Results:1 The BMI,ALT,AST,GGT,FBG,TG and CAP in the case group were significantly higher than those in the control group,the difference was statistically significant(P<0.05).The control group HDL-C,HBcAb,type III procollagen amino terminal peptide,The type IV collagen,laminin and LSM were higher than the case group,the difference was statistically significant(P<0.05).The case group was more likely to be associated with complications,and the difference was statistically significant(P=0.01).2 Univariate analysis showed that About the author:Zhang Guoshun,male,chief physician,professor,master's tutor,doctoral,mainly engaged in research and prevention of liver diseases,13930565676,zguoshun@sina.com.Fund Project:China Hepatitis Prevention Foundation Funded Project(No.:TQGB20170015);Hebei Province Medical Science Research Key Project(No.20170933);North China University of Technology Graduate Innovation Project(No.2019S49)patients in the case group had BMI≥25Kg/m2,GGT>45U/L,type IV collagen≤140ng/ml,laminin≤140ng/ml,CAP≥283dB/m,hyperglycemia,high glycerol The proportion of patients with lipemia was significantly higher than that of the control group,the difference was statistically significant(P<0.05);3 binary logistic regression analysis showed that GGT,FBG,BMI,laminin,CAP were predictive of chronic hepatitis B combined with non-An effective indicator of alcoholic fatty liver disease.Conclusion 1GGT,BMI,FBG,laminin and CAP are the influencing factors of CHB combined with NAFLD.The occurrence of 2NAFLD is closely related to obesity,hyperglycemia and hypertriglyceridemia.The HBcAb and liver fibrosis indexes are decreased when CHB combined with NAFLD,and the mechanism is still unclear.
文摘Objective: To explore the fatal risk factors of liver cirrhosis complicated with the first upper gastrointestinal bleeding, so as to provide reference for clinical prevention and treatment. Methods: 572 patients with cirrhosis admitted to North China University of Science and Technology and Tangshan Infectious Diseases Hospital from January 2014 to January 2018 were selected. According to whether there is concurrent upper gastrointestinal bleeding, it is divided into 163 cases of hemorrhage group and 409 cases of non-bleeding group. The patients in the hemorrhagic group were divided into case group (65 cases died of first upper gastrointestinal bleeding) and control group (98 cases died of non-first upper gastrointestinal bleeding). The general clinical data, laboratory and imaging data of the patients were analyzed. The risk factors of upper gastrointestinal bleeding in cirrhosis and the independent risk factors of the first upper gastrointestinal bleeding in cirrhosis were analyzed. Results: (1) Univariate analysis showed that: there were significant differences in Hb, PLT, CHE, ALB, TBIL, PT, left gastric vein diameter, portal vein diameter, course of cirrhosis, family history of cirrhosis, Child classification of liver function, esophagogastric varices, ascites, hepatic encephalopathy and portal vein thrombosis between hemorrhagic and non-hemorrhagic groups (P<0.05). The difference was statistically significant;(2) Multivariate logistic regression analysis showed that the diameter of left gastric vein, esophageal varices, ascites, Child C grade of liver function and portal vein thrombosis were risk factors for upper gastrointestinal bleeding in patients with cirrhosis. Left gastric vein diameter, esophagogastric varices and portal vein thrombosis are independent risk factors for first upper gastrointestinal bleeding in cirrhosis. Conclusion:Wider internal diameter of left gastric vein, severe esophagogastric varices and portal vein thrombosis are independent risk factors for fatal upper gastrointestinal bleeding in cirrhosis.
文摘The non-noble metal modified sulfated zirconia was found easy to deactivate.Herein,highly active and highly stable non-noble core-shell Ni-S_(2)O_(8)^(2−)/Al_(2)O_(3)@ZrO_(2) catalysts(Ni-SA@Z-x,x=Al content in wt%)have been successfully prepared and investigated for n-pentane isomerization.The results showed that the core-shell Ni-SA@Z-30 provided a sustained high isopentane yield(63.1%)with little or no deactivation within 5000 min at a mild reaction pressure of 2.0 MPa,which can be attributed to the following factors:(i)carbon deposition was greatly suppressed by the large pore size and huge pore volume;(ii)the loss of sulfur entities was suppressed because the small and highly dispersed tetragonal ZrO_(2) particles can bond with the S species strongly;(iii)strong Brønsted acidity can be maintained well after the isomerization.The pore structures and acid nature of the core-shell Ni-SA@Z-x are entirely different from those of the normal structure Ni-S_(2)O_(8)^(2−)/ZrO_(2)-Al_(2)O_(3),even though the Al content and the compositions of the individual components are the same.The Al_(2)O_(3)cores endow the catalysts with high internal surface area and high mechanical strength.Meanwhile,the ZrO_(2) shell,which consists of more and smaller tetragonal ZrO_(2) particles because of the large surface area of the Al_(2)O_(3)core,promotes the formation of more stable sulfur species and stronger binding sites.