An energy-saving and eco-friendly method for the efficient construction of various tri-and tetrasubstituted pyrrolecarbonitriles through ultrasound-assisted multicomponent tandem reaction of readily available alkenes,...An energy-saving and eco-friendly method for the efficient construction of various tri-and tetrasubstituted pyrrolecarbonitriles through ultrasound-assisted multicomponent tandem reaction of readily available alkenes,TMSCN and N,N-disubstituted formamides within 40 min under metal-,solvent-free and mild conditions was developed.The dual role of iodine(catalyst and oxidant)notably simplified the reaction conditions and reduced the chemical waste generated.展开更多
基金the Hunan Provincial Natural Science Foundation of China(Nos.2018JJ3215 and 2019JJ20008)the Research Foundation of Education Bureau of Hunan Province(No.18C0147)Double first-class construction project of Hunan Agricultural University(No.SYL2019064)。
文摘An energy-saving and eco-friendly method for the efficient construction of various tri-and tetrasubstituted pyrrolecarbonitriles through ultrasound-assisted multicomponent tandem reaction of readily available alkenes,TMSCN and N,N-disubstituted formamides within 40 min under metal-,solvent-free and mild conditions was developed.The dual role of iodine(catalyst and oxidant)notably simplified the reaction conditions and reduced the chemical waste generated.
