Dear Editor,Toxoplasma gondii is broadly distributed worldwide,and infects nearly all warm-blooded animals(Montoya and Liesenfeld,2004).Its primary infections in pregnant women may lead to abortion,stillbirth and othe...Dear Editor,Toxoplasma gondii is broadly distributed worldwide,and infects nearly all warm-blooded animals(Montoya and Liesenfeld,2004).Its primary infections in pregnant women may lead to abortion,stillbirth and other conditions,and it also attributes largely to encephalitis,retinochoroiditis and other serious diseases in immunocompromised individuals(Moncada and Montoya,2012).Rac1 is a small GTPase in the Rho family that plays an important role in cytoskeleton reorganization(Hall,1998).Rac1 GTPase is reported to be activated by infection of Chlamydia pneumoniae(Zhang et al.,2014).展开更多
基金This work was supported by the National Key Research and Development Program of China(2017YFD0500400)the National Natural Science Foundation of China(81772217,20180907,81572012,81802024)+4 种基金Postdoctoral Science Foundation of China(2017M622734)Guangdong Provincial Natural Science Foundation Project(2016A030311025,2017A030313694,2018A030313217)Science and Technology Planning Project of Guangdong Province(2018A050506038)Guangzhou health and medical collaborative innovation major special project(201604020011)Guangdong Medical Scientific Research Foundation(B2018071)。
文摘Dear Editor,Toxoplasma gondii is broadly distributed worldwide,and infects nearly all warm-blooded animals(Montoya and Liesenfeld,2004).Its primary infections in pregnant women may lead to abortion,stillbirth and other conditions,and it also attributes largely to encephalitis,retinochoroiditis and other serious diseases in immunocompromised individuals(Moncada and Montoya,2012).Rac1 is a small GTPase in the Rho family that plays an important role in cytoskeleton reorganization(Hall,1998).Rac1 GTPase is reported to be activated by infection of Chlamydia pneumoniae(Zhang et al.,2014).
