<strong>Background:</strong><span style="white-space:normal;font-size:10pt;font-family:;" "=""><strong> </strong>Arrhythmias after acute myocardial infarctio...<strong>Background:</strong><span style="white-space:normal;font-size:10pt;font-family:;" "=""><strong> </strong>Arrhythmias after acute myocardial infarction are common. Bra</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">dyarrhythmias need specific insight into when and how to treat them. <b>Objective</b></span><b style="white-space:normal;"><span style="font-size:10pt;font-family:;" "="">s</span><span style="font-size:10pt;font-family:;" "="">: </span></b><span style="white-space:normal;font-size:10pt;font-family:;" "="">To delineate the incidence, course, and management of different types of</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">bradyarrhythmia</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">s</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> after acute myocardial infarction, </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">the </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">study period was five years. <b>Methods: </b>453 patients with Acute Myocardial Infarction (AMI) were admitted to intensive care in five years. ECGs were analyzed for the presence of bra</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">dyarrhythmias and details of management. <b>Results: </b>65 patients with bradycardia were found. Sinus bradycardia </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 40, sick sinus syndrome </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 10, junctional rhy</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">thm </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 10, second-degree block</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 10, complete heart block </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 24. We divided patients with sinus bradycardia into </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">a </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">stable </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">group </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">and </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">an </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">unstable</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> group</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">. Unstable sinus bradycardia is more prevalent in cases with hypotension or shock, slower heart rates, gross or transmural infarction</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">.</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> Also</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">,</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> predictors of instability were ch</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">angeable morphology of the </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">“</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">P</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">”</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> wave and inferior rather than anterior infarction</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">.</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">The indications and danger of atropine are defined. Complete heart block was found in 24 patients (0.053%). 13 were managed by drug therapy (isoprenaline, corticosteroids, and atropine);</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">Eleven patients were paced</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">. 14 out of the 24 patients died (58%), the total mortality rate among the 453 patients was 22%. The</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> prognostic factors of CHB were defined. Techniques of introduc</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">tion of the</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> lead in RV without fluoroscopy are described. <b>Conclusions:</b> Sinus bradycardia in AMI is accompanied by a lower incidence of mortality. Atropine is not a safe drug to be given as routine. Complete heart block predictors of mortality are the association with heart failure, early-onset, and persistence of the block.</span>展开更多
文摘<strong>Background:</strong><span style="white-space:normal;font-size:10pt;font-family:;" "=""><strong> </strong>Arrhythmias after acute myocardial infarction are common. Bra</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">dyarrhythmias need specific insight into when and how to treat them. <b>Objective</b></span><b style="white-space:normal;"><span style="font-size:10pt;font-family:;" "="">s</span><span style="font-size:10pt;font-family:;" "="">: </span></b><span style="white-space:normal;font-size:10pt;font-family:;" "="">To delineate the incidence, course, and management of different types of</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">bradyarrhythmia</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">s</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> after acute myocardial infarction, </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">the </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">study period was five years. <b>Methods: </b>453 patients with Acute Myocardial Infarction (AMI) were admitted to intensive care in five years. ECGs were analyzed for the presence of bra</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">dyarrhythmias and details of management. <b>Results: </b>65 patients with bradycardia were found. Sinus bradycardia </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 40, sick sinus syndrome </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 10, junctional rhy</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">thm </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 10, second-degree block</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 10, complete heart block </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">in</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> 24. We divided patients with sinus bradycardia into </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">a </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">stable </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">group </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">and </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">an </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">unstable</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> group</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">. Unstable sinus bradycardia is more prevalent in cases with hypotension or shock, slower heart rates, gross or transmural infarction</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">.</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> Also</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">,</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> predictors of instability were ch</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">angeable morphology of the </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">“</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">P</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">”</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> wave and inferior rather than anterior infarction</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">.</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">The indications and danger of atropine are defined. Complete heart block was found in 24 patients (0.053%). 13 were managed by drug therapy (isoprenaline, corticosteroids, and atropine);</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">Eleven patients were paced</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">. 14 out of the 24 patients died (58%), the total mortality rate among the 453 patients was 22%. The</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> prognostic factors of CHB were defined. Techniques of introduc</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">tion of the</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> lead in RV without fluoroscopy are described. <b>Conclusions:</b> Sinus bradycardia in AMI is accompanied by a lower incidence of mortality. Atropine is not a safe drug to be given as routine. Complete heart block predictors of mortality are the association with heart failure, early-onset, and persistence of the block.</span>