Two alkaloids tylophoridicine D (1) and tylophoridicine E (2) have been isolated from Tylophora atrofolliculata. The structures of the compounds were elucidated on the basis of spect -roscopic analysis.
A new ionone glycoside （6R,9R）-blumenyl α-L-rhamnopyranosyl-（1 → 6）-β-D-gluco-pyranoside （1）, together with a new natural product 2-methoxyl-4-trans-pmpenyl-phenol α-L-rhamnopyranosyl-（1 → 6）-β-D-glucopy...A new ionone glycoside （6R,9R）-blumenyl α-L-rhamnopyranosyl-（1 → 6）-β-D-gluco-pyranoside （1）, together with a new natural product 2-methoxyl-4-trans-pmpenyl-phenol α-L-rhamnopyranosyl-（1 → 6）-β-D-glucopyranoside （2）, was isolated from the leaves ofNeoalsomitra integrifoliola. Their structures were elucidated by chemical and spectral analysis. Compound 1 showed weak anti-inflammatory and low-level antioxidant activities.展开更多
Two new styryllactones, iso-goniopypyrone and 8-acetyl-9-deoxygoniopypyrone, were isolated from the roots of Goniothalamus cheliensis. Their structure were elucidated on the basis of spectroscopic and chemical eviden...Two new styryllactones, iso-goniopypyrone and 8-acetyl-9-deoxygoniopypyrone, were isolated from the roots of Goniothalamus cheliensis. Their structure were elucidated on the basis of spectroscopic and chemical evidences.展开更多
Triptophenolide methyl ether and iso-triptophenolidemethl ether were synthesized from triptophenolide .It is comfirmed that the triptophenolide structure which DFYu reported in 1990 is not corect by analysis of 1HNMR...Triptophenolide methyl ether and iso-triptophenolidemethl ether were synthesized from triptophenolide .It is comfirmed that the triptophenolide structure which DFYu reported in 1990 is not corect by analysis of 1HNMR and (13)CNMR data of these two compounds.展开更多
A new isocoumarin,tenuissimasatin（1）,was isolated from metabolites of the endophytic fungus Alternaria tenuissima（Nees ＆ T.Nees：Fr.） Wiltshire,which was isolated from the bark of Erythrophleum fordii Oliver,toge...A new isocoumarin,tenuissimasatin（1）,was isolated from metabolites of the endophytic fungus Alternaria tenuissima（Nees ＆ T.Nees：Fr.） Wiltshire,which was isolated from the bark of Erythrophleum fordii Oliver,together with 11 known compounds（2- 12）.The structure and absolute configuration of 1 was determined by means of NMR and CD analysis.Compound 3 shows selective cytotoxic activity on human colon cancer cell HCT-8（IC_（50） = 1.78μmol/L） by MTT test in vitro.Other compounds show no such activities（IC_（50）〉10μmol/L）.展开更多
基金The financial support of the Nationat Key Basic R&D(973)Programe(No.G1998-05l120)are grafefully acknowleged
文摘Two alkaloids tylophoridicine D (1) and tylophoridicine E (2) have been isolated from Tylophora atrofolliculata. The structures of the compounds were elucidated on the basis of spect -roscopic analysis.
基金the National science fund for Distinguished Young Scholars (No.30625040)the Key Project of Natural Science Foundation of China (No.20432030)+1 种基金"973"Project (No.2004CB518906)PCSIRT (No.IRT0514).
文摘A new ionone glycoside （6R,9R）-blumenyl α-L-rhamnopyranosyl-（1 → 6）-β-D-gluco-pyranoside （1）, together with a new natural product 2-methoxyl-4-trans-pmpenyl-phenol α-L-rhamnopyranosyl-（1 → 6）-β-D-glucopyranoside （2）, was isolated from the leaves ofNeoalsomitra integrifoliola. Their structures were elucidated by chemical and spectral analysis. Compound 1 showed weak anti-inflammatory and low-level antioxidant activities.
文摘Two new styryllactones, iso-goniopypyrone and 8-acetyl-9-deoxygoniopypyrone, were isolated from the roots of Goniothalamus cheliensis. Their structure were elucidated on the basis of spectroscopic and chemical evidences.
文摘Triptophenolide methyl ether and iso-triptophenolidemethl ether were synthesized from triptophenolide .It is comfirmed that the triptophenolide structure which DFYu reported in 1990 is not corect by analysis of 1HNMR and (13)CNMR data of these two compounds.
基金Financial support from the National Science and Technology Project of China(No2009ZX09311-004)the Natural Science Foundation of China(No201072234)
文摘A new isocoumarin,tenuissimasatin（1）,was isolated from metabolites of the endophytic fungus Alternaria tenuissima（Nees ＆ T.Nees：Fr.） Wiltshire,which was isolated from the bark of Erythrophleum fordii Oliver,together with 11 known compounds（2- 12）.The structure and absolute configuration of 1 was determined by means of NMR and CD analysis.Compound 3 shows selective cytotoxic activity on human colon cancer cell HCT-8（IC_（50） = 1.78μmol/L） by MTT test in vitro.Other compounds show no such activities（IC_（50）〉10μmol/L）.
基金supported by the National Natural Science Foundation of China(Nos.20772157 and 21132009)National Science and Technology Project of China(No.2011ZX09307-002-01)the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China(No.IRT1007)
