Objective:To evaluate the correlation of chronic periodontitis in tropical area and IFN- 7,IL-10 and IL-17 levels.Methods:One hundred and forty-eight patients and one hundred and thirty-two healthy control subjects we...Objective:To evaluate the correlation of chronic periodontitis in tropical area and IFN- 7,IL-10 and IL-17 levels.Methods:One hundred and forty-eight patients and one hundred and thirty-two healthy control subjects were included in the study.Clinical parameters(PI.CI and PD) and GCF levels of IFN- 7.II.—10 and IL-17 were measured at baseline,week 8,week 16 and week 24 after mechanical removal of dental plaque.IFN- 7 and IL-10 were determined with EL1SA methods and IL-17 was determined with the cytometric bead array.Results:Removal of dental plaque resulted in improvement in all clinical parameters.Meanwhile,GCF IL-17 declined to control levels,while GCF IFN- 7 and IL-10 levels remained unchanged.Conclusions:The decline of GCF IL-17 levels in patients with resolution of periodontitis suggests that IL-17 is involved in the periodontal inflammatory process.展开更多
基金supported by the National Natural Science Foundation of Hainan Province(Grant No:309067)
文摘Objective:To evaluate the correlation of chronic periodontitis in tropical area and IFN- 7,IL-10 and IL-17 levels.Methods:One hundred and forty-eight patients and one hundred and thirty-two healthy control subjects were included in the study.Clinical parameters(PI.CI and PD) and GCF levels of IFN- 7.II.—10 and IL-17 were measured at baseline,week 8,week 16 and week 24 after mechanical removal of dental plaque.IFN- 7 and IL-10 were determined with EL1SA methods and IL-17 was determined with the cytometric bead array.Results:Removal of dental plaque resulted in improvement in all clinical parameters.Meanwhile,GCF IL-17 declined to control levels,while GCF IFN- 7 and IL-10 levels remained unchanged.Conclusions:The decline of GCF IL-17 levels in patients with resolution of periodontitis suggests that IL-17 is involved in the periodontal inflammatory process.
