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嗜酸细胞性胃肠炎27例临床病例分析 被引量:6
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作者 程玉 谭诗云 +1 位作者 李明 马凤梅 《中国内镜杂志》 2020年第8期6-12,共7页
目的探讨嗜酸细胞性胃肠炎(EGE)的临床病例特点,提高对EGE的认识水平和诊治能力。方法回顾性分析2015年5月-2019年5月于武汉大学人民医院确诊的27例EGE患者的临床表现、实验室检查、超声检查、影像学检查、骨髓穿刺、消化道内镜检查、... 目的探讨嗜酸细胞性胃肠炎(EGE)的临床病例特点,提高对EGE的认识水平和诊治能力。方法回顾性分析2015年5月-2019年5月于武汉大学人民医院确诊的27例EGE患者的临床表现、实验室检查、超声检查、影像学检查、骨髓穿刺、消化道内镜检查、病理学检查和预后情况等资料,并对其进行随访。结果27例EGE患者发病年龄(40.78±21.53)岁,其中≥18岁的21例(77.8%),男性多于女性(2∶1),有过敏史或变态反应性疾病4例(14.8%)。临床表现为腹痛24例(88.9%),腹泻14例(51.9%);病程2 d^8年,中位病程6个月。外周血嗜酸性粒细胞(EOS)增高17例(63.0%),EOS百分比增高17例(63.0%);13例行外周血免疫球蛋白E(IgE)检验,其中8例(61.5%)升高。14例行腹部超声检查,6例(42.9%)提示腹腔大量积液,腹水均为渗出液,其中4例(66.7%)腹水病理提示EOS增多。25例行CT检查,提示消化道管壁增厚11例(44.0%),腹腔积液11例(44.0%),腹腔淋巴结增大9例(36.0%)。2例行CT小肠造影(CTE)检查,提示病变均位于空肠。25例行内镜及组织活检病理检查,内镜下外观无明显特异性,病变位于胃部11例(44.0%),结直肠7例(28.0%),黏膜充血或红斑共9例(36.0%),糜烂共8例(32.0%)。6例行骨髓穿刺及病理检查,骨髓病理提示4例(66.7%)有EOS浸润。4例有过敏史的患者均行食物剔除治疗。经激素或保守治疗后,病情稳定或好转15例(55.6%),复发6例(22.2%)。非参数检验结果提示:性别、年龄、过敏和临床分型与治疗前后EOS数值变化无关(P>0.05);激素治疗与治疗前后EOS数值变化有关(P<0.05)。结论EGE患者常以腹痛、腹泻等胃肠道症状就诊,常伴有EOS增高,内镜和影像学检查无明显特异性,但内镜、影像学、腹水、骨髓穿刺及相关病理活检对EGE确诊具有重要作用;糖皮质激素治疗较非糖皮质激素治疗的患者EOS下降更快。 展开更多
关键词 嗜酸细胞性胃肠炎 嗜酸性粒细胞 内镜 病理 糖皮质激素
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MiR-146a rs2910164 polymorphism increases risk of gastric cancer:A meta-analysis 被引量:4
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作者 Wen-Qun Xie shi-yun tan Xiao-Fan Wang 《World Journal of Gastroenterology》 SCIE CAS 2014年第41期15440-15447,共8页
AIM: To systematically evaluate the association between the miR-146a rs2910164 polymorphism and susceptibility to gastric cancer.
关键词 Gastric cancer MIR-146A POLYMORPHISM RISK META-ANALYSIS
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Gastric intramural hematoma accompanied by severe epigastric pain and hematemesis after endoscopic mucosal resection 被引量:2
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作者 Peng Sun shi-yun tan Guo-Hai Liao 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第47期7127-7130,共4页
Gastric intramural hematoma is a rare injury of the stomach,and is most often seen in patients with underlying disease.Such injury following endoscopic therapy is even rarer,and there are no universally accepted guide... Gastric intramural hematoma is a rare injury of the stomach,and is most often seen in patients with underlying disease.Such injury following endoscopic therapy is even rarer,and there are no universally accepted guidelines for its treatment.In this case report,we describe a gastric intramural hematoma which occurred within 6 h of endoscopic mucosal resection(EMR).Past medical history of this patient was negative,and laboratory examinations revealed normal coagulation profiles and platelet count.Following EMR,the patient experienced severe epigastric pain and vomited 150 mL of gastric contents which were bright red in color.Subsequent emergency endoscopy showed a 4 cm × 5 cm diverticulum-like defect in the anterior gastric antrum wall and a 4 cm × 8 cm intramural hematoma adjacent to the endoscopic submucosal dissection lesion.Following unsatisfactory temporary conservative management,the patient was treated surgically and made a complete recovery.Retrospectively,one possible reason for the patient's condition is that the arterioles in the submucosa or muscularis may have been damaged during deep and massive submucosal injection.Thus,endoscopists should be aware of this potential complication and improve the level of surgery,especially the skills required for submucosal injection. 展开更多
关键词 Gastric intramural hematoma Endoscopic mucosal resection COMPLICATION
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Status quo and influencing factors of comfort with touch among nursing staff in rehabilitation department:A cross-sectional study
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作者 Yun Jie TONG Dan-Dan LU +2 位作者 Mei-Fen LYU Yan-Mei LIU shi-yun tan 《Journal of Integrative Nursing》 2021年第3期122-127,共6页
Objective:The objective of this study is to investigate the current status of comfort with touch among nursing staff in the rehabilitation department and analyze its influencing factors.Materials and Methods:The conve... Objective:The objective of this study is to investigate the current status of comfort with touch among nursing staff in the rehabilitation department and analyze its influencing factors.Materials and Methods:The convenience sampling method was used to select 131 nursing staff in the rehabilitation department of 3A-level hospitals in Yunnan Province,China,from March to June 2020 to conduct a questionnaire survey.Results:The nurses’comfort with touch score of 131 clinical nurses in the rehabilitation department was 58.82±4.85.Multivariate regression analysis showed that compassion fatigue(t=‒2.968,P<0.01)and occupational social support(t=2.767,P<0.01)were the influencing factors of the physical comfort of nursing staff;average monthly income(t=‒2.160,P<0.05),occupational cognitive evaluation(t=4.924,P<0.01),and secondary traumatic stress(t=2.833,P<0.01)were the influencing factors of task-oriented contact among nursing staff;marital status(t=2.656,P<0.01)and occupational social support(t=2.078,P<0.05)were the influencing factors for private nursing comfort of nurses.Conclusion:The comfort with touch among nurses in the rehabilitation department is at a medium level.Nursing managers should pay attention to their comfort with touch.In order to promote the development of medical service,hospitals should constantly improve the security and social support of nursing practitioners from the aspects of system,management,and salary performance. 展开更多
关键词 Comfort with touch compassion fatigue nursing staff occupational identity REHABILITATION
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Primary Small Intestinal Diffuse Large B-cell Lymphoma Masquerading as Crohn&#39;s Disease: A Case Report 被引量:1
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作者 Xiao-Hong Lu Yuan-Jie Yu +1 位作者 shi-yun tan Yi-Juan Ding 《Chinese Medical Journal》 SCIE CAS CSCD 2017年第17期2138-2139,共2页
To the Editor:Early primary gastrointestinal non-Hodgkin&#39;s lymphoma represents a diagnostic challenge and may be easily misdiagnosed as Crohn&#39;s disease or intestinal tuberculosis.[1] Here,we describe a 58-y... To the Editor:Early primary gastrointestinal non-Hodgkin&#39;s lymphoma represents a diagnostic challenge and may be easily misdiagnosed as Crohn&#39;s disease or intestinal tuberculosis.[1] Here,we describe a 58-year-old man who was admitted due to recurrent colic in the middle and upper abdomen with intermittent vomiting for l 0 months.The colic was paroxysmal lasting from a few minutes to several hours without obvious triggers.His medical history was otherwise unremarkable.In November 2013,gastrointestinal endoscopy revealed gastroenteritis,and abdominal computed tomography (CT) showed jejunal wall edema and thickening.His symptoms did not improve after 1-month treatment for suspected gastroenteritis. 展开更多
关键词 B细胞淋巴瘤 原发性 小肠 弥漫性 克隆 伪装 断层扫描 胃肠道
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