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Genome editing of 30 UTR-embedded inhibitory region enables generation of gene knock-up alleles in plants
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作者 Hongwen Wang Dahan Zhang +7 位作者 Mingjiang Chen Xiangbing Meng shiwei bai Peiyong Xin Jijun Yan Jinfang Chu Jiayang Li Hong Yu 《Plant Communications》 SCIE CSCD 2024年第3期1-4,共4页
Dear Editor,Genome editing has revolutionized speed breeding by enabling researchers to alter the genome directly as desired(Gao,2021).The most widely used CRISPR–Cas9 technology has mainly been applied to engineer n... Dear Editor,Genome editing has revolutionized speed breeding by enabling researchers to alter the genome directly as desired(Gao,2021).The most widely used CRISPR–Cas9 technology has mainly been applied to engineer null mutations in coding sequences,with the goal of creating loss-of-function alleles.Recently,upstream regulatory elements of the promoter region and 50 upstream open reading frame(uORF)have been engineered to generate gain-of-function alleles,producing versatile cis-regulatory effects,usually through changes in gene expression levels(Rodrıguez-Leal et al.,2017;Zhang et al.,2018;Song et al.,2022). 展开更多
关键词 UPSTREAM breeding VERSATILE
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用于不稳定原子核研究的共线激光谱仪研制进展 被引量:4
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作者 张鹏 刘寅绅 +11 位作者 白世伟 杨晓菲 王姝婧 刘永超 胡晗睿 郭洋帆 林喆阳 严周 杜泽宇 梅文聪 叶沿林 李奇特 《科学通报》 EI CAS CSCD 北大核心 2023年第9期1054-1065,共12页
不稳定原子核的基本性质是研究核结构的重要探针之一,有助于我们理解丰中子/丰质子核中出现的新奇物理现象,也是检验和发展核理论模型的重要依据.利用精密激光谱学技术测量核外电子的超精细结构光谱,可以精确提取不稳定原子核基态和长... 不稳定原子核的基本性质是研究核结构的重要探针之一,有助于我们理解丰中子/丰质子核中出现的新奇物理现象,也是检验和发展核理论模型的重要依据.利用精密激光谱学技术测量核外电子的超精细结构光谱,可以精确提取不稳定原子核基态和长寿命同核异能态的自旋、磁矩、电四极矩和电荷半径等多个基本性质.本文简单介绍了国际上激光谱学技术的发展现状和超精细结构光谱的测量原理.在此基础上,详细介绍了在我国研制的基于荧光探测的共线激光谱系统及近期的优化升级现状.通过测量Ti原子和Ca离子的高分辨共振谱,有效验证了共线激光谱设备的整体性能.最后,结合我国现有和发展中放射性核束装置的物理目标,提出进一步优化升级激光谱技术,提高其分辨率和灵敏度,并用于不稳定核研究的计划. 展开更多
关键词 共线激光谱 超精细结构 不稳定原子核 荧光探测 离子探测
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Retrospective and perspective of rice breeding in China 被引量:21
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作者 shiwei bai Hong Yu +1 位作者 Bing Wang Jiayang Li 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2018年第11期603-612,共10页
Breeding is the art and science of selecting and changing crop traits for the benefit of human beings. For several decades, tremendous efforts have been made by Chinese scientists in rice breeding in improving grain y... Breeding is the art and science of selecting and changing crop traits for the benefit of human beings. For several decades, tremendous efforts have been made by Chinese scientists in rice breeding in improving grain yield, nutrition quality, and environmental performance, achieving substantial progress for global food security. Several generations of crop breeding technologies have been developed, for example,selection of better performance in the field among variants(conventional breeding), application of molecular markers for precise selection(molecular marker assisted breeding), and development of molecular design(molecular breeding by rational design). In this review, we briefly summarize the advances in conventional breeding, functional genomics for genes and networks in rice that regulate important agronomic traits, and molecular breeding in China with focuses on high yield, good quality,stress tolerance, and high nutrient-use efficiency. These findings have paved a new avenue for rational design of crops to develop ideal varieties with super performance and productivity. 展开更多
关键词 Rice breeding HETEROSIS Breeding by rational design Molecular breeding
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Enhanced monopole transition strength from the cluster decay of ^(13)C
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作者 Jun Feng YanLin Ye +26 位作者 Biao Yang ChengJian Lin HuiMin Jia DanYang Pang ZhiHuan Li JianLing Lou QiTe Li XiaoFei Yang Jing Li HongLiang Zang Qiang Liu Wei Jiang ChenGuang Li Yang Liu ZhiQiang Chen HongYi Wu ChunGuang Wang Wei Liu Xiang Wang JingJing Li DiWen Luo Ying Jiang shiwei bai JinYan Xu NanRu Ma LiJie Sun DongXi Wang 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2019年第1期49-55,共7页
The inelastic excitations and cluster decay of ^(13)C have been measured using the reaction,9Be(^(13)C, ^(13)C* →~9Be + α)~9Be. We observe strong excitation to the 14.3-MeV(1/2-) resonant state from the cluster-deca... The inelastic excitations and cluster decay of ^(13)C have been measured using the reaction,9Be(^(13)C, ^(13)C* →~9Be + α)~9Be. We observe strong excitation to the 14.3-MeV(1/2-) resonant state from the cluster-decay channel, leading to an enhanced monopole matrix element of(6.3 ± 0.6) fm^2. This large cluster-related monopole strength is a clear indication of the cluster-structure domination of this state and is consistent with the recent prediction of the orthogonality condition model(OCM). It would be interesting to further explore the three-center molecular rotational band that is initiated from the observed band-head. 展开更多
关键词 INELASTIC EXCITATION MONOPOLE transition CLUSTER DECAY
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迈向育种5.0:智能品种的智能培育
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作者 余泓 白世伟 李家洋 《科学通报》 EI CAS 2024年第32期4687-4690,共4页
粮食安全一直是世界人口增长面临的最严峻挑战.1927年世界人口首次达到20亿,2022年突破80亿.在这100年人口的快速增长背后,育种技术的快速发展以及作物单产的大幅提高起到了决定性的支撑作用^([1,2]).根据联合国数据,预计2050年世界人... 粮食安全一直是世界人口增长面临的最严峻挑战.1927年世界人口首次达到20亿,2022年突破80亿.在这100年人口的快速增长背后,育种技术的快速发展以及作物单产的大幅提高起到了决定性的支撑作用^([1,2]).根据联合国数据,预计2050年世界人口将达到97亿,现有粮食增长率将无法满足人口增长的需求^([3]),函需下一代的育种革命进一步提升粮食产量,那么下一代育种技术核心是什么呢? 展开更多
关键词 粮食产量 粮食安全 世界人口增长 作物单产 育种技术 增长率
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