臭氧是一种环境友好型氧化剂,可直接用于消毒、杀菌和废水处理,对于维护和促进公共卫生安全至关重要.由于臭氧容易分解,不利于储存,因此需要现制即用.目前臭氧生成技术主要包括:电晕放电法和电催化臭氧生产(EOP)技术.相较于电晕放电法,...臭氧是一种环境友好型氧化剂,可直接用于消毒、杀菌和废水处理,对于维护和促进公共卫生安全至关重要.由于臭氧容易分解,不利于储存,因此需要现制即用.目前臭氧生成技术主要包括:电晕放电法和电催化臭氧生产(EOP)技术.相较于电晕放电法,EOP是一种本质安全的臭氧生产技术.然而,该工艺相较于电晕放电技术电能消耗量大,为了使其更具商业可行性,有必要开发高活性且低成本的电催化剂.此外,合理的电解槽设计对于实现高效EOP过程也至关重要.然而,目前研究主要集中在提高EOP催化剂活性方面,对电解槽的结构设计优化的关注较少.本文通过开发高效电催化剂进而将其应用于结构优化后的电解槽中,实现了更加高效的EOP过程.本文采用水热方法成功制备了一种具有较高EOP活性的方形氧化铅(PbO_(x)-CTAB-120)电催化剂.在标准三电极测试系统中,电流密度为50 mA cm^(-2)的测试条件下,法拉第效率(FE)可达20.7%,与商用β-PbO_(2)(17.1%)相比提高了21.1%.此外,设计了具有平行流场的可视化EOP电解槽,该可视化电解槽在传质和传热方面具有明显优势,有利于实现更加高效的EOP过程.将催化剂PbO_(x)-CTAB-120组装至可视化电解槽中,在1.0 A cm^(-2)的测试电流密度下,电解液为超纯水,该体系气态臭氧产量可以达到588 mg h^(-1)g^(-1)catalyst,比能量消耗(PEOP)为56 Wh g^(-1)gaseous ozone.体系臭氧产量约为商用β-PbO_(2)在传统电解槽中产量的2倍,并且PEOP降低率超过62%.原位18O同位素标记差分电化学质谱和密度泛函理论计算结果表明,PbO_(x)-CTAB-120电催化剂在EOP过程中遵循晶格氧机理路径,晶格氧迁移产生的氧空位能有效稳定OOH^(*)和O_(2)^(*)反应中间体,因此有利于催化剂在EOP过程中保持较好的反应活性和稳定性.同时,还利用先进的高速摄像可视化工具和计算流体力学(CFD)仿真模拟研究了平行流场EOP电解槽的运行过程和高效传质传热的原理.CFD模拟结果表明,与传统流场模型相比,平行流场对应的出口气泡停留时间更长,说明平行流场更有利于产物气泡从出口逸出,即气泡容易快速扩散,与实验结果一致.因此,PbO_(x)-CTAB-120电催化剂与新型可视化电解槽相结合,有助于在超纯水中实现较好的气态臭氧产率和较低比能耗.此外,二者的结合充分发挥了电催化剂的EOP活性和电解槽的传质特性所带来的优势,实现了反应性和传输性的协同增强,从而极大促进了原位有机污染物降解效率.综上所述,本文在制备高效阳极催化剂的基础上,同时利用优化电解槽结构实现了提升臭氧产率和降低过程能耗,为高活性电催化剂与优化的电解槽耦合以实现高效EOP过程及其有效应用提供参考.展开更多
To improve the efficiency of coal seam water injection,the influence of nanofluids on coal surface wettability was studied based on the nano drag reduction and injection enhancement technology in the field of tertiary...To improve the efficiency of coal seam water injection,the influence of nanofluids on coal surface wettability was studied based on the nano drag reduction and injection enhancement technology in the field of tertiary oil recovery.The composition optimization and performance evaluation of nanofluids with nano-silica and sodium lauryl sulfate as the main components were carried out,and the effects of the nanofluid with the optimal ratio on coal wettability were studied through spontaneous upward imbibition experiments.The results show that the composite nanofluid has a lower surface tension,and the lowest value of the interfacial tension is 15.79 m N/m.Therefore,the composite nanofluid can enhance the wettability of coal.However,its effects on coal samples with different metamorphic degrees is different,that is,low rank coal is the largest,middle rank coal is the second,and high rank coal is the least.In addition,a functional relationship between time and imbibition height is found for pulverized coal with different particle sizes.When the particle size of pulverized coal is 60–80 mesh,the wettability of nanofluid to coal is best.The findings in this paper provide a new perspective for improving the water injection efficiency for coal seams with low permeability.展开更多
The mechanical properties of metallic thin films deposited on a substrate play a crucial role in the performance of micro/nano-electromechanical systems(MEMS/NEMS)and flexible electronics. This article reviews ongoing...The mechanical properties of metallic thin films deposited on a substrate play a crucial role in the performance of micro/nano-electromechanical systems(MEMS/NEMS)and flexible electronics. This article reviews ongoing study on the mechanics of substrate-supported thin films, with emphasis on the experimental characterization techniques,such as the rule of mixture and X-ray tensile testing. In particular, the determination of interfacial adhesion energy, film deformation, elastic properties and Bauschinger effect are discussed.展开更多
The choice of support is one of the most significant components in the direct synthesis of H_(2)O_(2).Aiming to improvement of activity and selectivity of H_(2)O_(2) on Pd/TiO_(2) surface,we systematically investigate...The choice of support is one of the most significant components in the direct synthesis of H_(2)O_(2).Aiming to improvement of activity and selectivity of H_(2)O_(2) on Pd/TiO_(2) surface,we systematically investigated the important elementary steps on Pd/TiO_(2)-Vo@C,Pd/TiO_(2)-Vo,Pd/TiO_(2)-2 Vo,Pd/TiO_(2),and Pd/C using the first-principles calculations.The Bader charge analysis and charge density difference of O_(2) adsorption elucidate the relationship between the electronic distribution and chemisorption energy.The effective barrier analysis further enables to quantitatively estimate the reactivity of H_(2)O_(2) and H2O.We demonstrate unambiguously that the selectivity of H2O formation is boosted as the oxygen vacancy concentration raised.Moreover,the introduction of C into a TiO_(2) with appropriate oxygen vacancies can slightly reduce the effective barrier for H_(2)O_(2) formation and increase the effective barrier for H2O formation leading to a higher activity and selectivity of H_(2)O_(2) formation.Our finding suggests that carbon-doped oxygen vacancy TiO_(2) supported Pd is potential alternative catalyst compared with the Pd/TiO_(2).展开更多
In this paper, we demonstrate a new optical method for tiny strain measurements based on the principle of carrier fringes of moire interferometry. A cross-line grating with frequency of 1200 lp/mm is replicated on the...In this paper, we demonstrate a new optical method for tiny strain measurements based on the principle of carrier fringes of moire interferometry. A cross-line grating with frequency of 1200 lp/mm is replicated on the specimen surface, and the strain can be deduced from the changes in carrier fringes before and after the deformation of an object. Four coherent laser beams are used to obtain the carrier fringe patterns of field U and V. Both theoretical analysis and numerical simulation indicate that the ideal accuracy of strain can be controlled within a range of ±1με. Case study of a plane extension experiment shows that the measurement accuracy of strain can be controlled within the range of ±10με. The average strain values of every row of field U and every column of field V can be obtained by using this method, and approximated strain of every pixel in the whole-field can be further acquired, and thus it is possible to measure tiny strains occurred in a micro-field. The technology in this paper can provide comprehensive information for analyzing related mechanical content in the field of MEMS.展开更多
An experimental method for a single layer is extended to determine the elastic properties of nanostructured W/C u multilayers on a flexible substrate.The strain difference between the W/Cu-polyimide-W/Cu composite and...An experimental method for a single layer is extended to determine the elastic properties of nanostructured W/C u multilayers on a flexible substrate.The strain difference between the W/Cu-polyimide-W/Cu composite and the uncoated substrate,measured by dual digital image correlation,allows us to extract the effective Young's modulus of W/Cu multilayers(20 periods)equaling 216±13 GPa.Finite element method is then performed,which agrees well with the experiment and classical rule of mixture(ROM)theory demonstrating that the extension to multilayers is effective and reliable.The numerical analysis also interestingly shows that the strain difference is linearly related to the thickness ratio(W/Cu),periods and sublayer thickness,respectively.In contrast to ROM theory,this approach could potentially be used for the evaluation of properties and design of emerging/unknown functional multilayers,whether or not they are crystalline or amorphous.展开更多
In order to screen the pepper varieties suitable for planting in the solar greenhouse in Lhasa, variety comparison test was conducted to the continuous cropping of pepper in solar greenhouse. The results showed that Q...In order to screen the pepper varieties suitable for planting in the solar greenhouse in Lhasa, variety comparison test was conducted to the continuous cropping of pepper in solar greenhouse. The results showed that Qianlv Tianshi F_1, Oriental Changlong F_1 and Qujiao 1 F_1 had higher yields than the control, and significantly lower root incidence rates than the control. Therefore, the 3 varieties were suitable fro planting in Lhasa.展开更多
Silicon-based carbon composites are believed as promising anodes in the near future due to their outstanding specific capacity and relatively lower volume effect compared to pure silicon anodes.Herein,a multilayer sph...Silicon-based carbon composites are believed as promising anodes in the near future due to their outstanding specific capacity and relatively lower volume effect compared to pure silicon anodes.Herein,a multilayer spherical core-shell(M-SCS)electrode with a graphite framework prepared with Si@O-MCMB/C nanoparticles is developed,which aims to realize chemically/mechanically stability during the lithiation/delithiation process with high specific capacity.An electrochemical-/mechanical-coupling model for the M-SCS structure is established with various chemical/mechanical boundary conditions.The simulation of finite difference method(FDM)has been conducted based on the proposed coupling model,by which the diffusion-induced stress along both the radial and the circumferential directions is determined.Moreover,factors that influence the diffusion-induced stress of the M-SCS structure have been discussed and analyzed in detail.展开更多
The inadequate quantity of hydrogen peroxide(H_(2)O_(2))in cancer cells promptly results in the constrained success of chemodynamic therapy(CDT).Significant efforts made throughout the years;nevertheless,researchers a...The inadequate quantity of hydrogen peroxide(H_(2)O_(2))in cancer cells promptly results in the constrained success of chemodynamic therapy(CDT).Significant efforts made throughout the years;nevertheless,researchers are still facing the great challenge of designing a CDT agent and securing H_(2)O_(2) supply within the tumor cell.In this study,taking advantage of H_(2)O_(2) level maintenance mechanism in cancer cells,a nanozyme-based bimetallic metal-organic frameworks(MOFs)tandem reactor is fabricated to elevate intracellular H_(2)O_(2) levels,thereby enhancing CDT.In addition,under nearinfrared excitation,the upconversion nanoparticles(UCNPs)loaded into the MOFs can perform photocatalysis and generate hydrogen,which increases cellular susceptibility to radicals induced from H_(2)O_(2),inhibits cancer cell energy,causes DNA damages and induces tumor cell apoptosis,thus improving CDT therapeutic efficacy synergistically.The proposed nanozyme-based bimetallic MOFs-mediated CDT and UCNPs-mediated hydrogen therapy act as combined therapy with high efficacy and low toxicity.展开更多
Magnetosomes, synthesized by magnetotactic bacteria (MTB), have been used in nano- and biotechnological applications, owing to their unique properties such as superparamagnetism, uniform size distribution, excellent b...Magnetosomes, synthesized by magnetotactic bacteria (MTB), have been used in nano- and biotechnological applications, owing to their unique properties such as superparamagnetism, uniform size distribution, excellent bioavailability, and easily modifiable functional groups. In this review, we first discuss the mechanisms of magnetosome formation and describe various modification methods. Subsequently, we focus on presenting the biomedical advancements of bacterial magnetosomes in biomedical imaging, drug delivery, anticancer therapy, biosensor. Finally, we discuss future applications and challenges. This review summarizes the application of magnetosomes in the biomedical field, highlighting the latest advancements and exploring the future development of magnetosomes.展开更多
Machinery fault diagnosis has progressed over the past decades with the evolution of machineries in terms of complexity and scale. High-value machineries require condition monitoring and fault diagnosis to guarantee t...Machinery fault diagnosis has progressed over the past decades with the evolution of machineries in terms of complexity and scale. High-value machineries require condition monitoring and fault diagnosis to guarantee their designed functions and performance throughout their lifetime. Research on machinery Fault diagnostics has grown rapidly in recent years. This paper attempts to summarize and review the recent R&D trends in the basic research field of machinery fault diagnosis in terms of four main aspects: Fault mechanism, sensor technique and signal acquisition, signal processing, and intelligent diagnostics. The review discusses the special contributions of Chinese scholars to machinery fault diagnostics. On the basis of the review of basic theory of machinery fault diagnosis and its practical applications in engineering, the paper concludes with a brief discussion on the future trends and challenges in machinery fault diagnosis.展开更多
Recently tremendous progress has been evidenced by the advancements in developing innovative three-dimensional(3 D)scaffolds using various techniques for addressing the autogenous grafting of bone. In this work, we de...Recently tremendous progress has been evidenced by the advancements in developing innovative three-dimensional(3 D)scaffolds using various techniques for addressing the autogenous grafting of bone. In this work, we demonstrated the fabrication of porous polycaprolactone(PCL) scaffolds for osteogenic differentiation based on supercritical fluid-assisted hybrid processes of phase inversion and foaming. This eco-friendly process resulted in the highly porous biomimetic scaffolds with open and interconnected architectures. Initially, a 2^3 factorial experiment was designed for investigating the relative significance of various processing parameters and achieving better control over the porosity as well as the compressive mechanical properties of the scaffold. Then, single factor experiment was carried out to understand the effects of various processing parameters on the morphology of scaffolds. On the other hand, we encapsulated a growth factor, i.e., bone morphogenic protein-2(BMP-2), as a model protein in these porous scaffolds for evaluating their osteogenic differentiation. In vitro investigations of growth factor loaded PCL scaffolds using bone marrow stromal cells(BMSCs) have shown that these growth factor-encumbered scaffolds were capable of differentiating the cells over the control experiments. Furthermore, the osteogenic differentiation was confirmed by measuring the cell proliferation, and alkaline phosphatase(ALP) activity, which were significantly higher demonstrating the active bone growth. Together, these results have suggested that the fabrication of growth factor-loaded porous scaffolds prepared by the eco-friendly hybrid processing efficiently promoted the osteogenic differentiation and may have a significant potential in bone tissue engineering.展开更多
The oxygen evolution reaction(OER)and electrochemical ozone production(EOP)attracted considerable attention due to their wide applications in electrocatalysis,but the detailed reaction mechanism of product formation a...The oxygen evolution reaction(OER)and electrochemical ozone production(EOP)attracted considerable attention due to their wide applications in electrocatalysis,but the detailed reaction mechanism of product formation as well as the voltage effect on O_(2)/O_(3)formation still remains unclear.In this work,density functional theory calculations were used to systematically investigate the possible reaction mechanisms of OER and EOP on the PbO_(2)(110)surface,with the possible reaction network involving surface lattice oxygen atoms(LOM)proposed.The results show that the LOM-2 reaction pathway involving two surface lattice oxygen atoms(Olatt)and one oxygen atom from H_(2)O was the most thermodynamically reactive.Different potential determining step(PDS)was obtained depending on the multiple reaction pathway,and the results show that the facile diffusion of Olattwould proceed the LOM pathway and promote the formation of surface oxygen vacancies(O_(vac1)/O_(vac2)).Furthermore,O_(vac1)/O_(vac2)formation on the surface would trigger further reactions of H_(2)O adsorption and splitting,which refilled the oxygen vacancy and ensured the considerable stability of the PbO_(2)(110)surface.Multiple H_(2)O dissociation pathways were proposed on PbO_(2)(110)with oxygen vacancy sites:the acid-base interaction mechanism and the vacancy fulfilling mechanism.展开更多
Recently,hydrogels have gained enormous interest in three-dimensional(3D)bioprinting toward developing functional substitutes for tissue remolding.However,it is highly challenging to transmit electrical signals to cel...Recently,hydrogels have gained enormous interest in three-dimensional(3D)bioprinting toward developing functional substitutes for tissue remolding.However,it is highly challenging to transmit electrical signals to cells due to the limited electrical conductivity of the bioprinted hydrogels.Herein,we demonstrate the 3D bioprinting-assisted fabrication of a conductive hydrogel scaffold based on poly-3,4-ethylene dioxythiophene(PEDOT)nanoparticles(NPs)deposited in gelatin methacryloyl(GelMA)for enhanced myogenic differentiation of mouse myoblasts(C2C12 cells).Initially,PEDOT NPs are dispersed in the hydrogel uniformly to enhance the conductive property of the hydrogel scaffold.Notably,the incorporated PEDOT NPs showed minimal influence on the printing ability of GelMA.Then,C2C12 cells are successfully encapsulated within GelMA/PEDOT conductive hydrogels using 3D extrusion bioprinting.Furthermore,the proliferation,migration and differentiation efficacies of C2C12 cells in the highly conductive GelMA/PEDOT composite scaffolds are demonstrated using various in vitro investigations of live/dead staining,F-actin staining,desmin and myogenin immunofluorescence staining.Finally,the effects of electrical signals on the stimulation of the scaffolds are investigated toward the myogenic differentiation of C2C12 cells and the formation of myotubes in vitro.Collectively,our findings demonstrate that the fabrication of the conductive hydrogels provides a feasible approach for the encapsulation of cells and the regeneration of the muscle tissue.展开更多
文摘臭氧是一种环境友好型氧化剂,可直接用于消毒、杀菌和废水处理,对于维护和促进公共卫生安全至关重要.由于臭氧容易分解,不利于储存,因此需要现制即用.目前臭氧生成技术主要包括:电晕放电法和电催化臭氧生产(EOP)技术.相较于电晕放电法,EOP是一种本质安全的臭氧生产技术.然而,该工艺相较于电晕放电技术电能消耗量大,为了使其更具商业可行性,有必要开发高活性且低成本的电催化剂.此外,合理的电解槽设计对于实现高效EOP过程也至关重要.然而,目前研究主要集中在提高EOP催化剂活性方面,对电解槽的结构设计优化的关注较少.本文通过开发高效电催化剂进而将其应用于结构优化后的电解槽中,实现了更加高效的EOP过程.本文采用水热方法成功制备了一种具有较高EOP活性的方形氧化铅(PbO_(x)-CTAB-120)电催化剂.在标准三电极测试系统中,电流密度为50 mA cm^(-2)的测试条件下,法拉第效率(FE)可达20.7%,与商用β-PbO_(2)(17.1%)相比提高了21.1%.此外,设计了具有平行流场的可视化EOP电解槽,该可视化电解槽在传质和传热方面具有明显优势,有利于实现更加高效的EOP过程.将催化剂PbO_(x)-CTAB-120组装至可视化电解槽中,在1.0 A cm^(-2)的测试电流密度下,电解液为超纯水,该体系气态臭氧产量可以达到588 mg h^(-1)g^(-1)catalyst,比能量消耗(PEOP)为56 Wh g^(-1)gaseous ozone.体系臭氧产量约为商用β-PbO_(2)在传统电解槽中产量的2倍,并且PEOP降低率超过62%.原位18O同位素标记差分电化学质谱和密度泛函理论计算结果表明,PbO_(x)-CTAB-120电催化剂在EOP过程中遵循晶格氧机理路径,晶格氧迁移产生的氧空位能有效稳定OOH^(*)和O_(2)^(*)反应中间体,因此有利于催化剂在EOP过程中保持较好的反应活性和稳定性.同时,还利用先进的高速摄像可视化工具和计算流体力学(CFD)仿真模拟研究了平行流场EOP电解槽的运行过程和高效传质传热的原理.CFD模拟结果表明,与传统流场模型相比,平行流场对应的出口气泡停留时间更长,说明平行流场更有利于产物气泡从出口逸出,即气泡容易快速扩散,与实验结果一致.因此,PbO_(x)-CTAB-120电催化剂与新型可视化电解槽相结合,有助于在超纯水中实现较好的气态臭氧产率和较低比能耗.此外,二者的结合充分发挥了电催化剂的EOP活性和电解槽的传质特性所带来的优势,实现了反应性和传输性的协同增强,从而极大促进了原位有机污染物降解效率.综上所述,本文在制备高效阳极催化剂的基础上,同时利用优化电解槽结构实现了提升臭氧产率和降低过程能耗,为高活性电催化剂与优化的电解槽耦合以实现高效EOP过程及其有效应用提供参考.
基金supported by the National Natural Science Foundation of China(Nos.51974176,51934004,52174194)the Shandong Province Natural Science Foundation of Outstanding Youth Fund(ZR2020JQ22)+1 种基金the Shandong Province Colleges and Universities Youth Innovation and Technology Support Program(2019KJH006)the Special funds for Taishan scholar project(TS20190935)。
文摘To improve the efficiency of coal seam water injection,the influence of nanofluids on coal surface wettability was studied based on the nano drag reduction and injection enhancement technology in the field of tertiary oil recovery.The composition optimization and performance evaluation of nanofluids with nano-silica and sodium lauryl sulfate as the main components were carried out,and the effects of the nanofluid with the optimal ratio on coal wettability were studied through spontaneous upward imbibition experiments.The results show that the composite nanofluid has a lower surface tension,and the lowest value of the interfacial tension is 15.79 m N/m.Therefore,the composite nanofluid can enhance the wettability of coal.However,its effects on coal samples with different metamorphic degrees is different,that is,low rank coal is the largest,middle rank coal is the second,and high rank coal is the least.In addition,a functional relationship between time and imbibition height is found for pulverized coal with different particle sizes.When the particle size of pulverized coal is 60–80 mesh,the wettability of nanofluid to coal is best.The findings in this paper provide a new perspective for improving the water injection efficiency for coal seams with low permeability.
基金supported by the National Natural Science Foundation of China (Grants 11472186 and 11602083)the Natural Science Foundation of Hunan Province, China (Grant 2016JJ6044)
文摘The mechanical properties of metallic thin films deposited on a substrate play a crucial role in the performance of micro/nano-electromechanical systems(MEMS/NEMS)and flexible electronics. This article reviews ongoing study on the mechanics of substrate-supported thin films, with emphasis on the experimental characterization techniques,such as the rule of mixture and X-ray tensile testing. In particular, the determination of interfacial adhesion energy, film deformation, elastic properties and Bauschinger effect are discussed.
基金financial support from the National Natural Science Foundation of China(NSFC-21625604,91934302,and 22008211)Zhejiang Innovation Team(2017R5203)。
文摘The choice of support is one of the most significant components in the direct synthesis of H_(2)O_(2).Aiming to improvement of activity and selectivity of H_(2)O_(2) on Pd/TiO_(2) surface,we systematically investigated the important elementary steps on Pd/TiO_(2)-Vo@C,Pd/TiO_(2)-Vo,Pd/TiO_(2)-2 Vo,Pd/TiO_(2),and Pd/C using the first-principles calculations.The Bader charge analysis and charge density difference of O_(2) adsorption elucidate the relationship between the electronic distribution and chemisorption energy.The effective barrier analysis further enables to quantitatively estimate the reactivity of H_(2)O_(2) and H2O.We demonstrate unambiguously that the selectivity of H2O formation is boosted as the oxygen vacancy concentration raised.Moreover,the introduction of C into a TiO_(2) with appropriate oxygen vacancies can slightly reduce the effective barrier for H_(2)O_(2) formation and increase the effective barrier for H2O formation leading to a higher activity and selectivity of H_(2)O_(2) formation.Our finding suggests that carbon-doped oxygen vacancy TiO_(2) supported Pd is potential alternative catalyst compared with the Pd/TiO_(2).
基金the Basal Research Funds of National Defence Science and Technology
文摘In this paper, we demonstrate a new optical method for tiny strain measurements based on the principle of carrier fringes of moire interferometry. A cross-line grating with frequency of 1200 lp/mm is replicated on the specimen surface, and the strain can be deduced from the changes in carrier fringes before and after the deformation of an object. Four coherent laser beams are used to obtain the carrier fringe patterns of field U and V. Both theoretical analysis and numerical simulation indicate that the ideal accuracy of strain can be controlled within a range of ±1με. Case study of a plane extension experiment shows that the measurement accuracy of strain can be controlled within the range of ±10με. The average strain values of every row of field U and every column of field V can be obtained by using this method, and approximated strain of every pixel in the whole-field can be further acquired, and thus it is possible to measure tiny strains occurred in a micro-field. The technology in this paper can provide comprehensive information for analyzing related mechanical content in the field of MEMS.
基金This research is financially supported by the National Natural Science Foundation of China(Grant 11802156)China Postdoctoral Science Foundation(Grant 2018M641331)French Government Program“Investissements d’Avenir”(Labex Interactifs,Grant ANR-11-LABX-0017-01).
文摘An experimental method for a single layer is extended to determine the elastic properties of nanostructured W/C u multilayers on a flexible substrate.The strain difference between the W/Cu-polyimide-W/Cu composite and the uncoated substrate,measured by dual digital image correlation,allows us to extract the effective Young's modulus of W/Cu multilayers(20 periods)equaling 216±13 GPa.Finite element method is then performed,which agrees well with the experiment and classical rule of mixture(ROM)theory demonstrating that the extension to multilayers is effective and reliable.The numerical analysis also interestingly shows that the strain difference is linearly related to the thickness ratio(W/Cu),periods and sublayer thickness,respectively.In contrast to ROM theory,this approach could potentially be used for the evaluation of properties and design of emerging/unknown functional multilayers,whether or not they are crystalline or amorphous.
基金Supported by the National Spark Program of China(2014GA840003)
文摘In order to screen the pepper varieties suitable for planting in the solar greenhouse in Lhasa, variety comparison test was conducted to the continuous cropping of pepper in solar greenhouse. The results showed that Qianlv Tianshi F_1, Oriental Changlong F_1 and Qujiao 1 F_1 had higher yields than the control, and significantly lower root incidence rates than the control. Therefore, the 3 varieties were suitable fro planting in Lhasa.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12072229 and 11602167).
文摘Silicon-based carbon composites are believed as promising anodes in the near future due to their outstanding specific capacity and relatively lower volume effect compared to pure silicon anodes.Herein,a multilayer spherical core-shell(M-SCS)electrode with a graphite framework prepared with Si@O-MCMB/C nanoparticles is developed,which aims to realize chemically/mechanically stability during the lithiation/delithiation process with high specific capacity.An electrochemical-/mechanical-coupling model for the M-SCS structure is established with various chemical/mechanical boundary conditions.The simulation of finite difference method(FDM)has been conducted based on the proposed coupling model,by which the diffusion-induced stress along both the radial and the circumferential directions is determined.Moreover,factors that influence the diffusion-induced stress of the M-SCS structure have been discussed and analyzed in detail.
基金funded by the National Natural Science Foundation of China(NSFC 81971734,32071323,32271410)the Science and Technology Projects in Fujian Province(2022FX1,2023Y4008)the Open Research Fund of Academy of Advanced Carbon Conversion Technology,Huaqiao University(AACCT0004).
文摘The inadequate quantity of hydrogen peroxide(H_(2)O_(2))in cancer cells promptly results in the constrained success of chemodynamic therapy(CDT).Significant efforts made throughout the years;nevertheless,researchers are still facing the great challenge of designing a CDT agent and securing H_(2)O_(2) supply within the tumor cell.In this study,taking advantage of H_(2)O_(2) level maintenance mechanism in cancer cells,a nanozyme-based bimetallic metal-organic frameworks(MOFs)tandem reactor is fabricated to elevate intracellular H_(2)O_(2) levels,thereby enhancing CDT.In addition,under nearinfrared excitation,the upconversion nanoparticles(UCNPs)loaded into the MOFs can perform photocatalysis and generate hydrogen,which increases cellular susceptibility to radicals induced from H_(2)O_(2),inhibits cancer cell energy,causes DNA damages and induces tumor cell apoptosis,thus improving CDT therapeutic efficacy synergistically.The proposed nanozyme-based bimetallic MOFs-mediated CDT and UCNPs-mediated hydrogen therapy act as combined therapy with high efficacy and low toxicity.
基金support from the National Natural Science Foundation of China(32171337)the National Marine Economic Innovation and Development Project(16PYY007SF17).Thi。
文摘Magnetosomes, synthesized by magnetotactic bacteria (MTB), have been used in nano- and biotechnological applications, owing to their unique properties such as superparamagnetism, uniform size distribution, excellent bioavailability, and easily modifiable functional groups. In this review, we first discuss the mechanisms of magnetosome formation and describe various modification methods. Subsequently, we focus on presenting the biomedical advancements of bacterial magnetosomes in biomedical imaging, drug delivery, anticancer therapy, biosensor. Finally, we discuss future applications and challenges. This review summarizes the application of magnetosomes in the biomedical field, highlighting the latest advancements and exploring the future development of magnetosomes.
基金Acknowledgements This work was partly supported by the National Key Basle Research Program of China (Grant No. 2015CB057400), the National Natural Science Foundation of China (Grant Nos. 51421004 and 51605366), and by the Fundamental Research Funds for the Central Universities.
文摘Machinery fault diagnosis has progressed over the past decades with the evolution of machineries in terms of complexity and scale. High-value machineries require condition monitoring and fault diagnosis to guarantee their designed functions and performance throughout their lifetime. Research on machinery Fault diagnostics has grown rapidly in recent years. This paper attempts to summarize and review the recent R&D trends in the basic research field of machinery fault diagnosis in terms of four main aspects: Fault mechanism, sensor technique and signal acquisition, signal processing, and intelligent diagnostics. The review discusses the special contributions of Chinese scholars to machinery fault diagnostics. On the basis of the review of basic theory of machinery fault diagnosis and its practical applications in engineering, the paper concludes with a brief discussion on the future trends and challenges in machinery fault diagnosis.
基金supported by the National Natural Science Foundation of China (U1605225, 31570974, and 31470927)the Public Science and Technology Research Funds Projects of Ocean (201505029)+1 种基金the Promotion Program for Young and Middle-aged Teacher in Science and Technology Research of Huaqiao University (ZQN-PY107)the Program for Innovative Research Team in Science and Technology in Fujian Province University
文摘Recently tremendous progress has been evidenced by the advancements in developing innovative three-dimensional(3 D)scaffolds using various techniques for addressing the autogenous grafting of bone. In this work, we demonstrated the fabrication of porous polycaprolactone(PCL) scaffolds for osteogenic differentiation based on supercritical fluid-assisted hybrid processes of phase inversion and foaming. This eco-friendly process resulted in the highly porous biomimetic scaffolds with open and interconnected architectures. Initially, a 2^3 factorial experiment was designed for investigating the relative significance of various processing parameters and achieving better control over the porosity as well as the compressive mechanical properties of the scaffold. Then, single factor experiment was carried out to understand the effects of various processing parameters on the morphology of scaffolds. On the other hand, we encapsulated a growth factor, i.e., bone morphogenic protein-2(BMP-2), as a model protein in these porous scaffolds for evaluating their osteogenic differentiation. In vitro investigations of growth factor loaded PCL scaffolds using bone marrow stromal cells(BMSCs) have shown that these growth factor-encumbered scaffolds were capable of differentiating the cells over the control experiments. Furthermore, the osteogenic differentiation was confirmed by measuring the cell proliferation, and alkaline phosphatase(ALP) activity, which were significantly higher demonstrating the active bone growth. Together, these results have suggested that the fabrication of growth factor-loaded porous scaffolds prepared by the eco-friendly hybrid processing efficiently promoted the osteogenic differentiation and may have a significant potential in bone tissue engineering.
基金National Key R&D Program of China(2021YFA1500900)National Natural Science Foundation of China(21625604,21878272,22141001).
文摘The oxygen evolution reaction(OER)and electrochemical ozone production(EOP)attracted considerable attention due to their wide applications in electrocatalysis,but the detailed reaction mechanism of product formation as well as the voltage effect on O_(2)/O_(3)formation still remains unclear.In this work,density functional theory calculations were used to systematically investigate the possible reaction mechanisms of OER and EOP on the PbO_(2)(110)surface,with the possible reaction network involving surface lattice oxygen atoms(LOM)proposed.The results show that the LOM-2 reaction pathway involving two surface lattice oxygen atoms(Olatt)and one oxygen atom from H_(2)O was the most thermodynamically reactive.Different potential determining step(PDS)was obtained depending on the multiple reaction pathway,and the results show that the facile diffusion of Olattwould proceed the LOM pathway and promote the formation of surface oxygen vacancies(O_(vac1)/O_(vac2)).Furthermore,O_(vac1)/O_(vac2)formation on the surface would trigger further reactions of H_(2)O adsorption and splitting,which refilled the oxygen vacancy and ensured the considerable stability of the PbO_(2)(110)surface.Multiple H_(2)O dissociation pathways were proposed on PbO_(2)(110)with oxygen vacancy sites:the acid-base interaction mechanism and the vacancy fulfilling mechanism.
基金support from the National Natural Science Foundation of China(NSFC,32071323,81971734 and 31800794)National Key R&D Program of China(2018YFB1105600)+3 种基金Natural Science Foundation of Fujian Province(2019J01076)support by the Fundamental Research Funds for the Central Universities(ZQN-713)Funds for Foreign Experts from Ministry of Science and Technology,China(G20190013023)Program for Innovative Research Team in Science and Technology in Fujian Province.
文摘Recently,hydrogels have gained enormous interest in three-dimensional(3D)bioprinting toward developing functional substitutes for tissue remolding.However,it is highly challenging to transmit electrical signals to cells due to the limited electrical conductivity of the bioprinted hydrogels.Herein,we demonstrate the 3D bioprinting-assisted fabrication of a conductive hydrogel scaffold based on poly-3,4-ethylene dioxythiophene(PEDOT)nanoparticles(NPs)deposited in gelatin methacryloyl(GelMA)for enhanced myogenic differentiation of mouse myoblasts(C2C12 cells).Initially,PEDOT NPs are dispersed in the hydrogel uniformly to enhance the conductive property of the hydrogel scaffold.Notably,the incorporated PEDOT NPs showed minimal influence on the printing ability of GelMA.Then,C2C12 cells are successfully encapsulated within GelMA/PEDOT conductive hydrogels using 3D extrusion bioprinting.Furthermore,the proliferation,migration and differentiation efficacies of C2C12 cells in the highly conductive GelMA/PEDOT composite scaffolds are demonstrated using various in vitro investigations of live/dead staining,F-actin staining,desmin and myogenin immunofluorescence staining.Finally,the effects of electrical signals on the stimulation of the scaffolds are investigated toward the myogenic differentiation of C2C12 cells and the formation of myotubes in vitro.Collectively,our findings demonstrate that the fabrication of the conductive hydrogels provides a feasible approach for the encapsulation of cells and the regeneration of the muscle tissue.