Chinese guideline has proven effective in the fight against coronavirus disease 2019(COVID-19)during the global spread of the epidemic.Traditional Chinese medicine(TCM)is widely recognized for its effectiveness in all...Chinese guideline has proven effective in the fight against coronavirus disease 2019(COVID-19)during the global spread of the epidemic.Traditional Chinese medicine(TCM)is widely recognized for its effectiveness in alleviating symptoms,inhibiting disease progress,reducing mortality,and improving the cure rate of patients with COVID-19.During the pandemic,“three medicines and three formulas”(TMTFs)stood out from hundreds of others in registered clinical studies,which became highly recommended as TCM for COVID-19 treatment.The TMTFs not only effectively relieve the clinical symptoms of fever,cough,fatigue,and phlegm,but also substantially shorten the time of nucleic acid negative conversion,improve lung computed tomography imaging features and inflammation,ameliorate clinical biochemical indicators,and reduce sequelae.Their potential pharmacological mechanisms are mainly related to the crosstalk between viral toxicity,endothelial damage,cytokine storm,immune response,and microthrombus.In brief,the clinical effects and the potential mechanisms of TMTFs on COVID-19 were systematically analyzed and summarized covering the entirety of disease development,including virus invasion and replication,immune response and cytokine storm,and acute respiratory distress syndrome and multiple organ dysfunction syndrome.This review provides a theoretical basis and reference for the in-depth understanding of the positive role of TMTFs in COVID-19 treatment.展开更多
China has a vast land area and frequent interconnections between various regions.China's transportation industry is faced with tremendous pressure.This article combines China’s railway and highway transportation ...China has a vast land area and frequent interconnections between various regions.China's transportation industry is faced with tremendous pressure.This article combines China’s railway and highway transportation conditions to predict China’s economic development,uses stepwise regression to screen explanatory variables,and finally determines railway passenger turnover,road freight volume and passenger car ownership as the explanatory variables,and GDP as the dependent variable,and also analyzes China’s economic development by establish ing a multiple regression model.展开更多
The dividends of listed companies are related to external factors such as the macroeconomic situation and the industry level of these companies.They may also be related to internal factors such as the company's fi...The dividends of listed companies are related to external factors such as the macroeconomic situation and the industry level of these companies.They may also be related to internal factors such as the company's financial status,equity structure,and their development cycle.This article analyzes the non-dividend listed companies in terms of the external and internal factors;focusing on industries with more non-dividend listed companies.展开更多
基金supported by grants from the National Science Foundation of China (NSFC 82104431)Open project of State Key Laboratory of Component-based Chinese Medicine (CBCM2020201)+1 种基金the National Key R&D Program of China (2020YFA0708004)Tianjin Education Commission Scientific Research Project (2022KJ148).
文摘Chinese guideline has proven effective in the fight against coronavirus disease 2019(COVID-19)during the global spread of the epidemic.Traditional Chinese medicine(TCM)is widely recognized for its effectiveness in alleviating symptoms,inhibiting disease progress,reducing mortality,and improving the cure rate of patients with COVID-19.During the pandemic,“three medicines and three formulas”(TMTFs)stood out from hundreds of others in registered clinical studies,which became highly recommended as TCM for COVID-19 treatment.The TMTFs not only effectively relieve the clinical symptoms of fever,cough,fatigue,and phlegm,but also substantially shorten the time of nucleic acid negative conversion,improve lung computed tomography imaging features and inflammation,ameliorate clinical biochemical indicators,and reduce sequelae.Their potential pharmacological mechanisms are mainly related to the crosstalk between viral toxicity,endothelial damage,cytokine storm,immune response,and microthrombus.In brief,the clinical effects and the potential mechanisms of TMTFs on COVID-19 were systematically analyzed and summarized covering the entirety of disease development,including virus invasion and replication,immune response and cytokine storm,and acute respiratory distress syndrome and multiple organ dysfunction syndrome.This review provides a theoretical basis and reference for the in-depth understanding of the positive role of TMTFs in COVID-19 treatment.
文摘China has a vast land area and frequent interconnections between various regions.China's transportation industry is faced with tremendous pressure.This article combines China’s railway and highway transportation conditions to predict China’s economic development,uses stepwise regression to screen explanatory variables,and finally determines railway passenger turnover,road freight volume and passenger car ownership as the explanatory variables,and GDP as the dependent variable,and also analyzes China’s economic development by establish ing a multiple regression model.
文摘The dividends of listed companies are related to external factors such as the macroeconomic situation and the industry level of these companies.They may also be related to internal factors such as the company's financial status,equity structure,and their development cycle.This article analyzes the non-dividend listed companies in terms of the external and internal factors;focusing on industries with more non-dividend listed companies.
