[Objectives]The paper was to investigate the protective effect of Fufang Yatongding on experimental periodontitis in rats.[Methods]Experimental periodontitis rats were randomly divided into blank group(5 rats),model g...[Objectives]The paper was to investigate the protective effect of Fufang Yatongding on experimental periodontitis in rats.[Methods]Experimental periodontitis rats were randomly divided into blank group(5 rats),model group,control group and experimental group,with 8 rats in each group.The rats in the blank group were fed with normal diet,and those in the model group,control group and experimental group were administered intragastrically with normal saline,minocycline hydrochloride solution and Fufang Yatongding solution,respectively.After 4 weeks,alveolar bone resorption was measured.Serum matrix metalloproteinases(MMPs)and inflammatory factors were detected by ELISA,and the changes in gingival tissue were observed by HE staining.[Results]Compared with the control group,the distance from enamel cementum to alveolar crest in the experimental group was decreased(P<0.05).Compared with the control group,the levels of serum MMPs and inflammatory factors in the experimental group were decreased(P<0.05).The results of HE staining showed that the cells in the gingival tissue of rats in the blank group were normal in morphology and intact in structure,and the cells in the gingival tissue of rats in the model group were damaged and out of order,while the cells in the control group were slightly intact and arranged orderly,and the pathological damage of rats in the experimental group was less than that in the control group.[Conclusions]Fufang Yatongding has protective effect on experimental periodontitis in rats by inhibiting the release of MMPs and inflammatory factors.展开更多
Barium tungstate of homogeneous double cone structure was synthesized by microwave synthesis method with sodium tungstate, barium nitrate as raw materials, polyethylene glycol (PEG2000) as surfactant. The as-prepared ...Barium tungstate of homogeneous double cone structure was synthesized by microwave synthesis method with sodium tungstate, barium nitrate as raw materials, polyethylene glycol (PEG2000) as surfactant. The as-prepared sample was characterized by X-ray diffraction (XRD), scanning electron micrograph (SEM) and photoluminescence spectrum (PL). The XRD Pattern showed that the samples are scheelite structure of BaWO4. The SEM image showed that the majority of as-prepared sample is a double cone structure, and some particles are attached to it. The length of most of the double cone is 10 μm. PL spectra showed that as-prepared sample had strong luminescence properties, and it had purity green emission at 495 nm and 521 nm. The effects of different surface active agent on the luminescence properties were studied. The results showed that when PEG2000 is as surfactant, the luminescence intensity of as-prepared sample was maximum.展开更多
基金Supported by Science and Technology Project of Ji’an City(2020-075)。
文摘[Objectives]The paper was to investigate the protective effect of Fufang Yatongding on experimental periodontitis in rats.[Methods]Experimental periodontitis rats were randomly divided into blank group(5 rats),model group,control group and experimental group,with 8 rats in each group.The rats in the blank group were fed with normal diet,and those in the model group,control group and experimental group were administered intragastrically with normal saline,minocycline hydrochloride solution and Fufang Yatongding solution,respectively.After 4 weeks,alveolar bone resorption was measured.Serum matrix metalloproteinases(MMPs)and inflammatory factors were detected by ELISA,and the changes in gingival tissue were observed by HE staining.[Results]Compared with the control group,the distance from enamel cementum to alveolar crest in the experimental group was decreased(P<0.05).Compared with the control group,the levels of serum MMPs and inflammatory factors in the experimental group were decreased(P<0.05).The results of HE staining showed that the cells in the gingival tissue of rats in the blank group were normal in morphology and intact in structure,and the cells in the gingival tissue of rats in the model group were damaged and out of order,while the cells in the control group were slightly intact and arranged orderly,and the pathological damage of rats in the experimental group was less than that in the control group.[Conclusions]Fufang Yatongding has protective effect on experimental periodontitis in rats by inhibiting the release of MMPs and inflammatory factors.
文摘Barium tungstate of homogeneous double cone structure was synthesized by microwave synthesis method with sodium tungstate, barium nitrate as raw materials, polyethylene glycol (PEG2000) as surfactant. The as-prepared sample was characterized by X-ray diffraction (XRD), scanning electron micrograph (SEM) and photoluminescence spectrum (PL). The XRD Pattern showed that the samples are scheelite structure of BaWO4. The SEM image showed that the majority of as-prepared sample is a double cone structure, and some particles are attached to it. The length of most of the double cone is 10 μm. PL spectra showed that as-prepared sample had strong luminescence properties, and it had purity green emission at 495 nm and 521 nm. The effects of different surface active agent on the luminescence properties were studied. The results showed that when PEG2000 is as surfactant, the luminescence intensity of as-prepared sample was maximum.