Sclerosing mediastinitis is a very rare benign disorder characterised by the d evelopment of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon e...Sclerosing mediastinitis is a very rare benign disorder characterised by the d evelopment of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon especially in areas wit hout endemic histoplasmosis. We report a Japanese boy with markedly elevated ser um inflammatory markers for more than 1 year in the absence of any clinical mani festations. 67Gascintigraphy demonstrated an accumulation in the mediastinal reg ion and an open biopsy revealed a hard fibrous mass in the anteriosuperior media stinum. Thus, a diagnosis of idiopathic sclerosing mediastinitis was made. Concl usion:To the best of our knowledge, this case is the youngest patient reported w ith this disorder. In patients with mediastinal mass lesions the diagnosis of sc lerosing mediastinitis should be considered as well as infectious, autoimmune or neoplastic disease even in children.展开更多
文摘Sclerosing mediastinitis is a very rare benign disorder characterised by the d evelopment of dense fibrous tissue within the mediastinum. Affected patients are typically young adults with infant cases being uncommon especially in areas wit hout endemic histoplasmosis. We report a Japanese boy with markedly elevated ser um inflammatory markers for more than 1 year in the absence of any clinical mani festations. 67Gascintigraphy demonstrated an accumulation in the mediastinal reg ion and an open biopsy revealed a hard fibrous mass in the anteriosuperior media stinum. Thus, a diagnosis of idiopathic sclerosing mediastinitis was made. Concl usion:To the best of our knowledge, this case is the youngest patient reported w ith this disorder. In patients with mediastinal mass lesions the diagnosis of sc lerosing mediastinitis should be considered as well as infectious, autoimmune or neoplastic disease even in children.
