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Orthographic,Semantic,and Contextual Influences on Initial Processing and Learning of Novel Words During Reading:Evidence From Eye Movements 被引量:2
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作者 Wei YI shiyi lu Robert DEKEYSER 《Chinese Journal of Applied Linguistics》 2022年第2期194-219,316,317,共28页
This study investigates how orthographic,semantic and contextual variables—including word length,concreteness,and contextual support—impact on the processing and learning of new words in a second language(L2)when fi... This study investigates how orthographic,semantic and contextual variables—including word length,concreteness,and contextual support—impact on the processing and learning of new words in a second language(L2)when first encountered during reading.Students learning English as a foreign language(EFL)were recruited to read sentences for comprehension,embedded with unfamiliar L2 words that occurred once.Immediately after this,they received a form recognition test,a meaning recall test,and a meaning recognition test.Eye-movement data showed significant effects of word length on both early and late processing of novel words,along with effects of concreteness only on late-processing eye-tracking measures.Informative contexts were read slower than neutral contexts,yet contextual support did not show any direct influence on the processing of novel words.Interestingly,initial learning of abstract words was better than concrete words in terms of form and meaning recognition.Attentional processing of novel L2 words,operationalized by total reading time,positively predicted L2 learners’recognition of new orthographic forms.Taken together,these results suggest:1)orthographic,semantic and contextual factors play distinct roles for initial processing and learning of novel words;2)online processing of novel words contributes to L2 learners’initial knowledge of unfamiliar lexical items acquired from reading. 展开更多
关键词 word processing/learning wordlength CONCRETENESS contextual support eye tracking
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转录组测序揭示细胞周期通路参与鸡腹脂沉积 被引量:6
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作者 陈家辉 任学义 +9 位作者 李丽敏 卢诗意 程湉 谭量天 梁少东 何丹林 罗庆斌 聂庆华 张细权 罗文 《遗传》 CAS CSCD 北大核心 2019年第10期962-973,共12页
近年来,随着生长性状和饲料转化率的提高,中国地方品种肉鸡腹脂率不断增加,大大降低了肉鸡的品质。过多的腹脂沉积不仅降低了肉鸡的屠宰率和抗病力,而且由于脂肪较难处理,导致其被随意丢弃,污染环境。为了挖掘与中国地方品种肉鸡腹脂沉... 近年来,随着生长性状和饲料转化率的提高,中国地方品种肉鸡腹脂率不断增加,大大降低了肉鸡的品质。过多的腹脂沉积不仅降低了肉鸡的屠宰率和抗病力,而且由于脂肪较难处理,导致其被随意丢弃,污染环境。为了挖掘与中国地方品种肉鸡腹脂沉积相关的基因和调控通路,本研究对杏花鸡分别进行高脂和普通饲料的喂养,检测腹脂沉积情况,并利用转录组测序检测高脂饲养对肝脏和腹脂组织中基因表达的影响。结果表明,喂养两周后高脂组肉鸡腹脂重和腹脂率显著增加,且腹脂细胞的直径和面积也显著增大。对两组鸡的腹脂和肝脏进行转录组测序,发现在腹脂中显著差异表达基因主要富集于细胞周期通路、PPAR(peroxisome proliferator-activated receptor)信号通路和ECM(extracellular matrix)受体信号通路中;而在肝脏中,显著差异表达基因同样显著富集于细胞周期通路中,同时也显著富集于类固醇生物合成和PPAR信号通路中。通过分析腹脂和肝脏组织中共同差异表达的基因,发现这些基因同样显著富集于细胞周期中。进一步以鸡肝癌细胞系LMH(chicken hepatoma cell)细胞和鸡前脂肪细胞系ICP(immortalized chicken preadipocytes)细胞进行体外验证,利用高脂培养基和普通培养基进行培养,结果发现48h后,高脂培养基可显著促进细胞周期进程,增加处于S期的细胞数。同时,qRT-PCR结果发现高脂培养基可显著促进细胞周期相关基因的表达。综上所述,本研究通过基因表达差异分析,发现高脂饲养可能通过激活鸡脂肪组织的细胞周期来促进前脂肪细胞增殖,进而增加腹脂沉积。该研究结果为进一步了解优质肉鸡腹脂沉积的机制提供了理论依据。 展开更多
关键词 杏花鸡 高脂饲料 腹脂沉积 细胞周期 差异表达基因
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