A non-two-dimensional van der Waals In Se semispherical array grown by vapor-liquid-solid method for hydrogen evolution

Two-dimensional(2D)layered materials with layer-number dependent properties are promising candidates for next-generation noble-metal-free electrocatalytic reaction.However,the main group metal chalcogenides(MMCs)used for this purpose are rarely explored.Herein,we report the controlled growth of indium selenide(In Se)with a novel morphology(semispherical array)on a silicon substrate and its application in hydrogen evolution reaction(HER).The formation of the spherical InSe is explained with a vapor-liquid-solid growth mechanism,in which the distribution and size of the spheres could be facilely tuned by the reaction parameters.The InSe semispherical array was demonstrated as more efficient catalyst for HER than the flake-like 2D InSe counterparts,originating from the fully exposed InSe spherical surface with abundant adsorbing sites and the high crystalline quality for electron transport.This work provides a controlled synthesis way of the layered In Se with a distinct spherical morphology used for the electrocatalysis applications and could be extended to other main group metal chalcogenides.

Integrated Exploration Model for Concealed Ore Deposit:A Case Study from Shuitou Fluorite Deposit,Inner Mongolia,North China

The demand for fluorite resource is increasing rapidly as most fluorite deposits on Earth’s surface have been exhausted.The newly discovered fluorite deposits in Inner Mongolia are hosted by Permian metamorphosed sandy slate,intermediate-acid intrusive rocks and Cretaceous volcanic sedimentary rocks.The ore bodies are strictly controlled by faults and buried by cover rocks.The feasibility and effectiveness of multi-techniques for prospecting concealed fluorite ore bodies are evaluated,and 10 anomalies are delineated.On the basis of geological features and effectiveness of different methods,the optimum combinations of ore prospecting techniques are proposed for the exploration of zonal type and burial type concealed fluorite ore bodies.Based on comprehensive researches,an integrated exploration model is proposed:(i)select key prospecting targets based on geological backgrounds,regional geochemical anomalies of F and Ca,and remote sensing images;(ii)identify the spatial distribution of low resistivity anomaly and ore-controlling structure from geophysical survey;(iii)evaluate the mineralization potential in fault zone based on F and Ca anomalies in key sections selected from low resistivity anomaly zones;and(iv)evaluate the mineralization potential and reveal the spatial distribution of fluorite ore bodies and ore-controlling faults based on integrated geophysical and geochemical anomalies.The integrated exploration model is verified to be a powerful tool for prospecting concealed fluorite ore bodies in coverage area.

Application of BEMD in Extraction of Magnetic Anomaly Components Associated with Sn-W Polymetallic Mineralization in SE Yunnan,SW China

The tin(Sn)-tungsten(W)polymetallic ore concentrated district in SE Yunnan is distributed at the junction region of the Yangtze Block,the Cathaysian Block and the Indosinian Block,where there are several giant deposits of tin,tungsten,copper,silver,lead,zinc and indium closely associated with a large scale Late Cretaceous magmatism.Bi-dimensional empirical mode decomposition(BEMD)is used to extract aeromagnetic anomalous components at the survey scale of 1:200000 from the original aeromagnetic data of SE Yunnan.Four intrinsic mode functions(IMFs)and a residues component are obtained,which may reflect the geological structures and geological bodies at different spatial scales from high frequency to low frequency.The results are shown as follows:(1)Two different types of Precambrian basement in the study area were recognized:one is the Yangtze Block basement characterized by a strong positive magnetic anomaly,the other is the Cathaysian Block basement with a weak negative magnetic anomaly.The former consists of high grade metamorphic rocks including metamorphosed basic igneous rocks,while the latter consists of low grade metamorphosed sedimentary rocks.(2)The aeromagnetic anomalies associated with Sn-W polymetallic mineralization and related to granites in the study area illustrate a pattern of a skarnized alteration-mineralization zone with a positive ring magnetic anomaly enclosing a granitic intrusion with negative magnetic anomaly;(3)The ring positive magnetic anomaly zones enclosing the negative magnetic anomaly are defined as the SnW polymetallic ore-searching targets in the study area.

Enhanced porphyrin-based fluorescence imaging-guided photodynamic/photothermal synergistic cancer therapy by mitochondrial targeting

Mitochondria are the power plants of the cell and play key roles in activating the apoptotic pathway in cancer cells,which are readily susceptible to cytotoxic reactive oxygen species and temperature elevations.Herein,we develop a"nanomissile"that targets mitochondria to enhance tumor treatment effects by facilitating mitochondrial dysfunction and releasing cytochrome C to activate the apoptotic pathway of cancer cells under 650-nm laser irradiation.Porphyringrafted polydopamine nanomaterial(PTPF-MitP)is designed as a nanomissile,with integrated O;-evolving photodynamic therapy and moderate photothermal therapy,which can selectively deliver to the mitochondria through a targeting unit,MitP.The cytotoxicity of PTPF-MitP to human lung tumor cells is twice as high as that of PTPF that does not have mitochondrial targeting units.In addition,it represents a realtime visualization and highly efficient treatment for tumor sites in vivo.This development represents a viable strategy for cancer therapy.