Colorectal cancer (CRC) is a common cancer with high morbidity and mortality.1 Post-translational modification (PTM) of protein plays an important role in the pathogenesis of CRC. Lysine crotonylation (Kcr) is an impo...Colorectal cancer (CRC) is a common cancer with high morbidity and mortality.1 Post-translational modification (PTM) of protein plays an important role in the pathogenesis of CRC. Lysine crotonylation (Kcr) is an important type of PTM and has been proved evolutionarily conserved in eukaryotic cells from a wide range of species.2 However, the role of protein Kcr in the progression of CRC is unclear.展开更多
基金supported by Key Medical Science and Technology Program of Shanxi Province(No.2020XM01)Shanxi“1331 Project”Quality and Efficiency Improvement Plan(No.1331KFC)+1 种基金Shanxi University of Chinese Medicine Science and Technology Innovation Ability Training Project(No.2019PY-016)partially by the National Natural Science Foundation of China(No.82170523).
文摘Colorectal cancer (CRC) is a common cancer with high morbidity and mortality.1 Post-translational modification (PTM) of protein plays an important role in the pathogenesis of CRC. Lysine crotonylation (Kcr) is an important type of PTM and has been proved evolutionarily conserved in eukaryotic cells from a wide range of species.2 However, the role of protein Kcr in the progression of CRC is unclear.