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Gut-liver axis plays a role in hepatocarcinogenesis of patients with Crohn's disease 被引量:2
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作者 shu-mei zheng de-jun cui qin ouyang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第26期3171-3172,共2页
The development of hepatocellular carcinoma (HCC) is attributed to several factors, including chronic viral infection, alcohol consumption, exposure to aflatoxin 131 and metabolic disorders. Several recent reports h... The development of hepatocellular carcinoma (HCC) is attributed to several factors, including chronic viral infection, alcohol consumption, exposure to aflatoxin 131 and metabolic disorders. Several recent reports have shown that HCC can occur in patients with longstanding Crohn's disease (CD) in the absence of other underlying high-risk liver diseases. There may be an association between CD and hepatocarcinogenesis, however, the precise mechanism for this requires further investigations. 展开更多
关键词 Inflammatory bowel disease Crohn's disease Hepatocellular carcinoma Intestinal flora Aza-thioprine Enterohepatic circulation
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