鼻内镜术后并发下肢静脉血栓及肺栓塞的分析(附5例报告)

目的探讨鼻内镜术后下肢静脉血栓(LEVT)及肺栓塞(PE)的发生情况,旨在提高耳鼻喉科医生对术后LEVT和PE的认识和诊断水平,总结治疗经验。方法回顾性分析2020年1月-2021年7月该院耳鼻咽喉头颈外科5例鼻内镜术后并发LEVT及PE的患者的临床资料。结果5例患者鼻内镜术后均出现LEVT和PE,经抗凝治疗后安全出院。结论急性PE起病急,死亡率高,鼻内镜术后并发PE的发生率较低,以往没有得到耳鼻喉科医生的足够重视,通过分析病例和回顾文献,提高耳鼻喉科医生对鼻内镜术后患者血栓的预防和重视,降低血栓发生率,并及早进行干预,提高治愈率。

Poly-lactic acid and agarose gelatin play an active role in the recovery of spinal cord injury

Objective To investigate the role of poly-lactic acid and agarose gelatin in promoting the functional recovery of the injured spinal cord. Methods Poly-lactic acid ( PLA) or agarose was embedded in the space between two stumps of the hemisectioned spinal cord. Immunohistochemistry was used to show astroglia proliferation and the infiltration of RhoA-positive cells. Locomotor activity recovery was evaluated by testing the function of hindlimbs. Results Astrogli-as and RhoA labeled non-neuronal cells accumulated in the area adjacent to the implant, while the number of RhoA-positive cells was decreased dramatically in the absence of implant. Animals implanted with agarose gelatin recovered more quickly than those with PLA, concomitant with a higher survival rate of the neurons. Conclusion Both PLA and agarose gelatin benefited the recovery of spinal cord after injury by providing a scaffold for astroglia processes. Modulation of the rigidity, pore size and inner structure of PLA and agarose gelatin might make these biodegradable materials more effective in the regeneration of the central nervous system (CNS).

Simulation-based Optimal Design of α-β-γ-δ Filter

The existing third-order tracker known as α-β-γ-δ filter has been used for target tracking and predicting for years. The filter can track the target＇s position and velocity, but not the acceleration. To extend its capability, a new fourth-order target tracker called α-β-γ-δ filter is proposed. The main objective of this study was to find the optimal set of filter parameters that leads to minimum position tracking errors. The tracking errors between using the α-β-γ-δ filter and the α-β-γ-δ filter are compared. As a result, the new filter exhibits significant improvement in position tracking accuracy over the existing third-order filter, but at the expense of computational time in search of the optimal filter. To reduce the computational time, a simulation-based optimization technique via Taguchi method is introduced.

Ventilatory effect of normal frequency jet ventilation in non-intubated anesthesia in the treatment of the palmar hyperhidrosis

Objective: To evaluate the ventilatory effect of normal frequency jet ventilation via Wei jet nasal airway in non-intubated anesthesia in the treatment of the palmar hyperhidrosis (PH). Methods: 62 patients with PH undergoing video-assisted thoracoscopic sympathectomy, aged 18~35 years, ASA I-II, were randomized into two groups: intubated group (group T) and normal-frequency jet ventilation group (group J). After induction tracheal tubes were inserted in Group T and Wei nasal airway were inserted in group J. The heart rate(HR),saturation pulse oxygen (SPO2), mean artery pressure (MAP) and end-tidal carbon dioxide partial pressure (PETCO2) were recorded at following time points: before induction (T0),1 min after induction (T1), 1 min after tube insertion/ intubation (T2), when trocars were inserted and carbon dioxide was inflated (T3), during lung recruitment maneuver and the chest closure (T4), the moment of extubation (T5), 15 min after extubation (T6). Blood samples were taken from left radial artery for blood gas analysis to monitor carbon dioxide partial pressure, arterial oxygen partial pressure, PH ,the BE at T0, T4, T6.The duration of anesthesia, awaking time ,the dosage of the propofol and the remifentanil, the intraoperative and postoperative adverse events were recorded. Results: Compared with group T, the HR and MAP were more stable in group J. The awaking time in the group J were significantly shorter than those in group T (P<0.05), the dosage of the remifentanil in group J was significantly less than that in group T (P<0.05), The incidences of throat discomfort, nausea and vomiting were lower than those in group T (P<0.05). Conclusion: Normal-frequency jet ventilation via Wei jet nasal airway in non-intubated anesthesia in the treatment of the (PH)is feasible, which can reduce stress response and make hemodynamics stable without the complications of tracheal intubation.

Encapsulating a Ni（Ⅱ） molecular catalyst in photoactive metal–organic framework for highly efficient photoreduction of CO2

Photocatalytic reduction of CO2 to CO is a promising strategy for reducing atmospheric CO2 levels and storing solar radiation as chemical energy.Here,we demonstrate that a molecular catalyst[NiⅡ(bpet)(H2O)2]successfully encapsulated into a highly robust and visible-light responsive metal–organic framework(Ru-UiO-67)to fabricate composite catalysts for photocatalytic CO2 reduction.The composite Ni@Ru-UiO-67 photocatalysts show efficient visible-light-driven CO2 reduction to CO with a TON of 581 and a selectivity of 99% after 20-h illumination,because of the facile electron transfer from Ru-photosensitizer to Ni(Ⅱ)active sites in Ni@Ru-UiO-67 system.The mechanistic insights into photoreduction of CO2 have been studied based on thermodynamical,electrochemical,and spectroscopic investigation,together with density functional theory(DFT)calculations.This work shows that encapsulating molecular catalyst into photoactive MOF highlights opportunities for designing efficient,stable and recyclable photocatalysts.

Enhanced proton conductivity of Mo_(154)-based porous inorganic framework

The construction of inorganic porous frameworks from discrete polyoxometalate(POM)units is a major research challenge.Herein,a three-dimensional(3D)all-inorganic porous structure{Mo_(154)}_n that consists of classic Mo_(154)rings connected by Mo–O–Mo covalent bonds was synthesized.Interestingly,the proton conductivity of the 3D-{Mo_(154)}_n framework is 1.1×10^(-2)S cm^(-1)at 22℃and 100%relative humidity(RH),which is one of the highest proton conductivities reported thus far for POM-based conductive materials.Compared to the discrete{Mo_(154)}cluster and 1D-{Mo_(154)}_n,the enhanced conductivity of 3D-{Mo_(154)}_n suggests that assembling POM-based all-inorganic porous frameworks is a promising method for designing proton-conductive materials.