Background： Obstructive sleep apnea （OSA） syndrome has a negative impact on the health of millions of adolescents and youth. The aim of this study was to evaluate the associations of OSA syndrome with obesity and c...Background： Obstructive sleep apnea （OSA） syndrome has a negative impact on the health of millions of adolescents and youth. The aim of this study was to evaluate the associations of OSA syndrome with obesity and cardiometabolic risk factors among adolescents and youth at risk for metabolic syndrome （MS）.Methods： A total of 558 subjects aged 14-28 years were recruited from the Beijing Child and Adolescent Metabolic Syndrome Study. Each underwent a 2-h oral glucose tolerance test （OGTT）, echocardiography, and liver ultrasonography. Anthropometric measures, blood levels of glucose, lipids, and liver enzymes were assessed. Subjects with high or low risk for OSA were identified by Berlin Questionnaire （BQ）. Results： Among the subjects in obesity, 33.7% of whom were likely to have OSAby BQ. Subjects with high risk for OSA had higher neck and waist circumference and fat mass percentage compared to those with low risk for OSA （P 〈 0.001 ）. Moreover, significant differences in levels of lipids, glucose after OGTT, and liver enzymes, as well as echocardiographic parameters were found between the two groups with high or low risk for OSA （P 〈 0.05）. The rates of nonalcoholic fatty liver disease （71.0% vs. 24.2%）, MS （38.9% vs. 7.0%）, and its components in high-risk group were significantly higher than in low-risk group. Conclusions： The prevalence of OSA by BQ was high in obese adolescents and youth. A high risk for OSA indicates a high cardiometabolic risk. Mechanisms mediating the observed associations require further investigation.展开更多
In this paper, the property of practical input-to-state stability and its application to stability of cascaded nonlinear systems are investigated in the stochastic framework. Firstly, the notion of （practical） stoch...In this paper, the property of practical input-to-state stability and its application to stability of cascaded nonlinear systems are investigated in the stochastic framework. Firstly, the notion of （practical） stochastic input-to-state stability with respect to a stochastic input is introduced, and then by the method of changing supply functions, （a） an （practical） SISS-Lyapunov function for the overall system is obtained from the corresponding Lyapunov functions for cascaded （practical） SISS subsystems.展开更多
文摘Background： Obstructive sleep apnea （OSA） syndrome has a negative impact on the health of millions of adolescents and youth. The aim of this study was to evaluate the associations of OSA syndrome with obesity and cardiometabolic risk factors among adolescents and youth at risk for metabolic syndrome （MS）.Methods： A total of 558 subjects aged 14-28 years were recruited from the Beijing Child and Adolescent Metabolic Syndrome Study. Each underwent a 2-h oral glucose tolerance test （OGTT）, echocardiography, and liver ultrasonography. Anthropometric measures, blood levels of glucose, lipids, and liver enzymes were assessed. Subjects with high or low risk for OSA were identified by Berlin Questionnaire （BQ）. Results： Among the subjects in obesity, 33.7% of whom were likely to have OSAby BQ. Subjects with high risk for OSA had higher neck and waist circumference and fat mass percentage compared to those with low risk for OSA （P 〈 0.001 ）. Moreover, significant differences in levels of lipids, glucose after OGTT, and liver enzymes, as well as echocardiographic parameters were found between the two groups with high or low risk for OSA （P 〈 0.05）. The rates of nonalcoholic fatty liver disease （71.0% vs. 24.2%）, MS （38.9% vs. 7.0%）, and its components in high-risk group were significantly higher than in low-risk group. Conclusions： The prevalence of OSA by BQ was high in obese adolescents and youth. A high risk for OSA indicates a high cardiometabolic risk. Mechanisms mediating the observed associations require further investigation.
基金the National Natural Science Foundation of China (No.60221301, No.60428304).
文摘In this paper, the property of practical input-to-state stability and its application to stability of cascaded nonlinear systems are investigated in the stochastic framework. Firstly, the notion of （practical） stochastic input-to-state stability with respect to a stochastic input is introduced, and then by the method of changing supply functions, （a） an （practical） SISS-Lyapunov function for the overall system is obtained from the corresponding Lyapunov functions for cascaded （practical） SISS subsystems.
