基于蚁群优化和模糊Petri网的建筑工程成本预测研究（英文）

为了有效提高建筑工程成本动态控制的精确度,提出将蚁群优化算法和模糊Petri网理论应用于建筑工程成本预测。首先,通过模糊产生式规则选择样本工程并确定工程之间的相似度,以便建立工程成本预测模型,其权值和阈值等参数由BP神经网络训练得出。然后,利用蚁群优化对模型各参数进行优化,从而进一步提高工程成本预测的精确度。实际建筑工程实例分析结果表明:相比传统的BP神经网络预测方法,提出的方法具有更高的准确度,能够有效应用于企业建筑工程成本的科学管理。

磁性压迫融合技术在原位肝移植术后胆道吻合口重度狭窄再通畅中的应用与配合技巧

目的探讨磁性压迫融合技术(MCA)在原位肝移植(OLT)后胆道吻合口重度狭窄中的应用及配合技巧。方法回顾性分析1例OLT术后胆道吻合口重度狭窄的患者临床资料,该患者采用常规方法治疗失败后改用MCA治疗,在X线监视下通过经皮经肝穿刺胆道成像(PTC)和内镜下逆行胰胆管造影术(ERCP),分别在狭窄近端与远端各置入1枚磁铁,确认2枚磁铁位置及轴向与胆管长轴平行、磁铁近端及远端在同一条直线上后,缓慢释放磁铁。结果 7 d后2枚磁铁完全融合并移位,PTC证实胆管狭窄段已再通。再经ERCP去除磁铁,并置入胆道全覆膜金属支架。结论 MCA用于常规方法治疗失败的重度胆管狭窄和完全性胆道梗阻患者,可压迫狭窄部位组织,形成新通道,使胆管狭窄再通。

Mechanical properties and durability of alkali-activated steel slag-blastfurnace slag cement

Alkali-activated cement(AAC)is either clinker-less or free,and it is also environmentally friendly due to its low carbon footprint and wide range sources.Industrial wastes,like steel slag and blastfurnace slag,usually have latent hydraulic reactivity,and can be used as precursors of AAC.Both clinkerless and clinker-free AAC were prepared from the mixture of steel slag and blastfurnace slag by using water glass as an activator,and four different recipes which satisfied the strength requirement of 42.5R Portland cement were obtained.Each recipe of AAC exhibited better resistance to sulfate attack and frost attack than Portland cement.AAC showed huge drying shrinkage,but it was equivalent to that of Portland cement as steel slag content increased to 40%.The AAC also had quite low risk of alkali-aggregate reaction.Microstructure analysis showed that the major products were calcium silicate hydrate(C–S–H),calcium aluminosilicate hydrate(C–A–S–H)and zeolite-like phases.Ettringite was also detected in the binder when gypsum was contained in the precursors.

Optimal harvesting of a hierarchical age-struetured population system

We investigate an optimal harvesting problem for age-structured species,in which elder individuals are more competitive than younger ones,and the population is modeled by a highly nonlinear integro-partial differential equation with a global feedback boundary condition.The existence of optimal strategies is established by means of compactness and maximizing sequences,and the maximum principle obtained via an adjoint system,tangent-normal cones and a new continuity result.In addition,some numerical experiments are presented to show the effects of the price function and younger's weight on the optimal profits.

The global dynamics of a discrete nonlinear hierarchical population system

This paper is concerned with the global dynamics of a hierarchical population model,in which the fertility of an individual depends on the total number of higher-ranking members.We investigate the stability of equilibria,nonexistence of periodic orbits and the persistence of the population by means of eigenvalues,Lyapunov function,and several results in discrete dynamical systems.Our work demonstrates that the reproductive number governs the evolution of the population.Besides the theoretical results,some numerical experiments are also presented.

Bioanalysis and Pharmacokinetics of Eight Active Components from Huanglian Jiedu Decoction in Rat Plasma by LC-ESI-MS/MS Method

Objective To develop a sensitive and rapid liquid chromatography-electrospray ionization-tandem mass spectrometry （LC-ESI-MS/MS） method for the simultaneous determination of wogonin, coptisine, berberine, palmatine, jatrorrhizine, phellodendrine, magnoflorine, and wogonoside in rat plasma and to evaluate the pharmacokinetic characteristics of Huanglian Jiedu Decoction （HJD）. Methods LC separation was performed on an Acquity HSS T3 column （100 mm × 2.1 mm, 1.8 μm） using gradient elution with the mobile phase consisting of acetonitrile and 0.1% formic acid water. The detection was accomplished by using positive electrospray ionization in multiple-reaction monitoring mode. Plasma samples were pretreated by protein precipitation. Results The method showed a good linearity over a wide concentration range （r^2 〉 0.99）. The lower limits of quantification were 0.20 ng/mL for coptisine and phellodendrine, 0.48 ng/mL for berberine, 0.10 ng/mL for jatrorrhizine, 0.32 ng/mL for magnoflorine, 0.30 ng/mL for palmatine, and 4.80 ng/mL for wogonin and wogonoside, respectively. The intra- and inter-day precision of the analytes was less than 12.11%, while the accuracy was between -14.46% and 4.86%. The mean recovery of all the analytes ranged from 93.10% to 110.91%. Conclusion This validated method offers thee advantages of high sensitivity. It is successfully applied to evaluating the pharmacokinetic properties of HJD.

Anion recognition with porphyrin-bottomed tetraurea receptors

Three tetraurea-appended porphyrin derivatives were synthesized and applied as anion receptors to complex with various anions, including F^-, Cl^-, Br^-, I^-, NO3^-, HSO4^-, and AcO^-. The binding stoichiometries were all measured to be 1：1 and high binding abilities of these receptors toward the anions were demonstrated with the association constants of up to 1.1 × 10^8 L/mol. The complexation of the receptors with anions was further unambiguously confirmed by single-crystal X-ray analysis

Crystal structures, antibacterial activity and thermal decomposition kinetics of lanthanide complexes with 4-chloro-2-methoxybenzoic acid and 1,10-phenanthroline

A series of lanthanide complexes [Ln(4-Cl-2-MOBA)3phen]2(Ln=Sm(1), Nd(2), Ho(3), Eu(4), Dy(5), and Tb(6); 4-Cl-2-MOBA=4-chloro-2-methoxybenzoate, phen=1,10-phenanthroline) were synthesized and characterized. The single-crystal X-ray diffraction demonstrates that 1–3 are isomorphous, which present dimeric structures with four 4-Cl-2-MOBA anions function as bridging ligands. Complexes 1 and 4–6 display their characteristic luminescence emission bands of central Ln3?ions. The heat capacities, the thermodynamic functions and the thermogravimetry–Fourier transform infrared spectra of gaseous products of complexes 1–6 were investigated.Their non-isothermal kinetics of the second decomposition stage was studied by the integral isoconversional non-linear method and Stark method. Furthermore, 1–6 exhibited excellent antibacterial activity against Candida albicans,Escherichia coli and Staphylococcus aureu.

Sesquiterpene lactones of Aucklandia lappa: Pharmacology,pharmacokinetics, toxicity, and structure–activity relationship

The medicinal part of Aucklandia lappa(Asteraceae) is its dried root,which is one of the commonly used Chinese medicinal materials.Here we reviewed sesquiterpene lactones isolated from A.lappa over the past ten years in the following aspects of pharmacological activities,pharmacokinetics,toxicology,structure-activity relationship.Pharmacological activities consist of anti-cancer,anti-inflammatory activity,anti-immunity activity,anti-oxidant activity,antimicrobial activity,spasmolytic activity and so on.The extractive,showing similar pharmacokinetics parameters,may exert their various biological activities by the interaction of their α-methylene-γ-butyrolactone moiety with the thiol groups of biomacromolecules through Michael-addition.However,the poor aqueous solubility,non-selective binding as a Michael acceptor at undesired targets limited clinical translation of this class.In order to evaluate the potential effect of the extractive applied in clinical trial,the present review outlines information on pharmacological activities,pharmacokinetics,toxicology,and structure-activity relationship,as well as the future research directions of the extractive for further development and utilization of A.lappa.