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The effect of pulse voltage rise rate on the polypropylene surface hydrophilic modification by ns pulsed nitrogen DBD
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作者 刘峰 李舒豪 +3 位作者 赵昱雷 Shakeel AKRAM 张丽 方志 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第10期6-14,共9页
The nanosecond(ns) pulsed nitrogen dielectric barrier discharge(DBD) is employed to enhance the hydrophilicity of polypropylene(PP) surface and improve its application effect.The discharge characteristics of the ns pu... The nanosecond(ns) pulsed nitrogen dielectric barrier discharge(DBD) is employed to enhance the hydrophilicity of polypropylene(PP) surface and improve its application effect.The discharge characteristics of the ns pulsed nitrogen DBD with different pulse rise times(from 50to 500 ns) are investigated by electrical and optical diagnostic methods and the discharge uniformity is quantitatively analyzed by image processing method.To characterize the surface hydrophilicity,the water contact angle(WCA) is measured,and the physical morphology and chemical composition of PP before and after modification are analyzed to explore the effect of plasma on PP surface.It is found that with increasing pulse rise time from 50 to 500 ns,DBD uniformity becomes worse,energy efficiency decreases from 20% to 10.8%,and electron density decrease from 6.6 × 10^(11)to 5.5 × 10^(11)cm^(-3).The tendency of electron temperature is characterized with the intensity ratio of N_(2)/N_(2)^(+)emission spectrum,which decreases from 17.4 to15.9 indicating the decreasing of T_(e) with increasing pulse rise time from 50 to 500 ns.The PP surface treated with 50 ns pulse rise time DBD has a lower WCA(~47°),while the WCA of PP treated with 100 to 500 ns pulse rise time DBD expands gradually(~50°–57°).According to the study of the fixed-point WCA values,the DBD-treated PP surface has superior uniformity under50 ns pulse rise time(3° variation) than under 300 ns pulse rise time(8° variation).After DBD treatment,the increased surface roughness from 2.0 to 9.8 nm and hydrophilic oxygencontaining groups on the surface,i.e.hydroxyl(-OH) and carbonyl(C=O) have played the significant role to improve the sample’s surface hydrophilicity.The short pulse voltage rise time enhances the reduced electric field strength(E/n) in the discharge space and improves the discharge uniformity,which makes relatively sufficient physical and chemical reactions have taken place on the PP surface,resulting in better treatment uniformity. 展开更多
关键词 dielectric barrier discharge pulse rise time material surface modification POLYPROPYLENE UNIFORMITY
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MRI化学位移成像和DWI评估肝癌病理分级的价值 被引量:10
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作者 杨震 周伟 +4 位作者 周丽 邹倩 郑甜 李淑豪 龚良庚 《中国肿瘤临床》 CAS CSCD 北大核心 2018年第18期959-963,共5页
目的:探讨基于化学位移效应的磁共振同反相位成像(MRI)和扩散加权成像(DWI)对肝细胞性肝癌(hepatocellular carcinoma,HCC)病理分级进行手术前评估的价值。方法:回顾性分析2016年1月至2017年12月南昌大学第二附属医院109例经病理证实为... 目的:探讨基于化学位移效应的磁共振同反相位成像(MRI)和扩散加权成像(DWI)对肝细胞性肝癌(hepatocellular carcinoma,HCC)病理分级进行手术前评估的价值。方法:回顾性分析2016年1月至2017年12月南昌大学第二附属医院109例经病理证实为HCC患者的术前MRI资料。处理Dixon同反相位成像及DWI序列图像,获得瘤内脂肪分数及最小ADC值。比较不同病理分化程度HCC瘤内实性成分脂肪分数和最小ADC值的差异;分析脂肪分数及最小ADC值与病理等级的相关性。应用ROC曲线确定不同病理分级HCC的脂肪分数、最小ADC值鉴别界值及其敏感度、特异度。结果:共纳入109例患者,低分化组24例,中分化组69例,高分化组16例。各病理分化组的脂肪分数、最小ADC值差异均有统计学意义。脂肪分数与病理分级呈正相关性(r=0.566,P<0.01)。脂肪分数预测低分化与中分化的界值为8.71%,敏感度为75.00%,特异度为67.19%,ROC曲线下面积为0.738;脂肪分数预测中分化与高分化的界值为5.53%,敏感度为71.87%,特异度为75.00%,ROC曲线下面积为0.843。最小ADC值与病理分级呈负相关性(r=-0.674,P<0.01)。最小ADC值预测低分化与中分化的界值为0.379×10^(-3)mm^2/s,敏感度为79.17%,特异度为84.37%,ROC曲线下面积为0.890;预测中分化与高分化的界值为0.532×10^(-3)mm^2/s,敏感度为89.06%,特异度为62.50%,ROC曲线下面积为0.812。结论:3D-Dixon成像和DWI在肝癌诊断及预后影响因素评估方面有较好的应用价值。脂肪分数和最小ADC值与HCC病理分级具有明显相关性,可作为无创性生物学指标评估肝细胞癌组织病理学因素。 展开更多
关键词 磁共振成像 化学位移同反相位成像 扩散加权成像 肝细胞性肝癌 组织分化
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Design and first result of combined Langmuir-magnetic probe on J-TEXT tokamak
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作者 Qinghu YANG Zhipeng CHEN +12 位作者 Zhigang HAO Yangming ZHAO Xin XU shuhao li Jie YANG Wei YAN Zhonghe JIANG Zhongyong CHEN Nengchao WANG Zhoujun YANG Yuan PAN Yonghua DING the J-TEXT Team 《Plasma Science and Technology》 SCIE EI CAS CSCD 2022年第5期39-47,共9页
In order to measure boundary electrostatic and magnetic fluctuations simultaneously,a combined Langmuir-magnetic probe(CLMP)has been designed and built on joint-Texas experimental tokamak.The probe consists of 8 graph... In order to measure boundary electrostatic and magnetic fluctuations simultaneously,a combined Langmuir-magnetic probe(CLMP)has been designed and built on joint-Texas experimental tokamak.The probe consists of 8 graphite probe pins and a 3D magnetic probe,driven by a mechanical pneumatic device.By means of simulation,the shielding effect of the graphite sleeve on the magnetic fluctuation signal is explored,and the influence of the eddy current was reduced by cutting the graphite sleeve.In the experiment,it has been verified that the mutual inductance of electromagnetic signals can be ignored,and a 70–90 k Hz electromagnetic mode is observed around the last closed magnetic surface.The establishment of CLMP provides data for the exploration of the coupling of electrostatic and magnetic fluctuations. 展开更多
关键词 J-TEXT Langmuir probe magnetic probe eddy current effect electromagnetic mode
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Towards advanced divertor configurations on the J-TEXT tokamak
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作者 Yunfeng liANG Zhipeng CHEN +24 位作者 Nengchao WANG Zhifeng CHENG Alexander KNIEPS Song ZHOU Bo RAO Shuai XU Philipp DREWS Xiaolong ZHANG Hao WANG Zhaosu WANG Jie YANG Xin XU Jiankun HUA Qinghu YANG Wei YAN Cunkai li Yutong YANG shuhao li Shaocheng liU lin NIE Ting LONG liang liAO Fuqiong WANG Yasuhiro SUZUKI the J-TEXT Team 《Plasma Science and Technology》 SCIE EI CAS CSCD 2022年第12期233-250,共18页
Developing advanced magnetic divertor configurations to address the coupling of heat and particle exhaust with impurity control is one of the major challenges currently constraining the further development of fusion r... Developing advanced magnetic divertor configurations to address the coupling of heat and particle exhaust with impurity control is one of the major challenges currently constraining the further development of fusion research.It has therefore become the focus of extensive attention in recent years.In J-TEXT,several new divertor configurations,including the high-field-side single-null poloidal divertor and the island divertor,as well as their associated fundamental edge divertor plasma physics,have recently been investigated.The purpose of this paper is to briefly summarize the latest progress and achievements in this relevant research field on J-TEXT from the past few years. 展开更多
关键词 DIVERTOR TOKAMAK magnetically confined fusion
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新型溶瘤病毒M1激活内质网应激致前列腺癌细胞凋亡的机制 被引量:1
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作者 刘硕儒 王功炜 +2 位作者 张斌 李书豪 胡成 《中华腔镜泌尿外科杂志(电子版)》 2023年第4期388-393,共6页
目的探讨新型溶瘤病毒M1对前列腺癌细胞的杀伤作用及其所引起凋亡的机理。方法通过四甲基偶氮唑盐比色法(MTT)检测不同滴度(0、0.001、0.01、0.1、1、10 PFU/cell)M1病毒对前列腺癌细胞进行48 h处理后细胞的存活率,通过流式细胞术检测... 目的探讨新型溶瘤病毒M1对前列腺癌细胞的杀伤作用及其所引起凋亡的机理。方法通过四甲基偶氮唑盐比色法(MTT)检测不同滴度(0、0.001、0.01、0.1、1、10 PFU/cell)M1病毒对前列腺癌细胞进行48 h处理后细胞的存活率,通过流式细胞术检测前列腺癌细胞凋亡的情况,通过蛋白标记(Western Blot)检测细胞内质网应激通路和凋亡通路的关键分子。结果与对照组(0 PFU/cell)相比,不同滴度(0.001、0.01、0.1、1、10 PFU/cell)溶瘤病毒M1能显著降低前列腺癌细胞存活率(P<0.05),且随着M1病毒剂量增加,前列腺癌细胞凋亡率显著上升(P<0.05)。蛋白标记(Western Blot)结果显示前列腺癌感染M1病毒后,内质网应激通路CHOP、Caspase 12、凋亡通路Cleaved-caspase 3蛋白显著上调(P<0.05)。结论新型溶瘤病毒M1可能通过引起前列腺癌细胞发生内质网应激而产生凋亡,最终杀伤前列腺癌细胞。 展开更多
关键词 溶瘤病毒 前列腺癌 PC-3M-2B4 PC-3 22Rv1 RWPE-1 细胞凋亡
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