Objective:To describe the anatomical characteristics and patterns of neurovascular compression (NVC) in patients suffering trigeminal neuralgia(TN) by 3D high-resolution magnetic resonance imaging(MRI) method and imag...Objective:To describe the anatomical characteristics and patterns of neurovascular compression (NVC) in patients suffering trigeminal neuralgia(TN) by 3D high-resolution magnetic resonance imaging(MRI) method and image fusion technique.Methods:The anatomic structure of trigeminal nerve,brain stem and blood vessel was observed in 100 consecutive TN patients by 3D high resolution MRI(3D SPGR,contrast-enhanced T1 3D MP-RAGE and T2/T1 3D FIESTA). The 3D image sources were fused and visualized using 3D DOCTOR software.Results:One or several NVC sites,which usually appeared 0-9.8 mm away from brain stem,were found on the symptomatic side in 93%of the TN cases.Superior cerebellar artery was involved in 76%(71/93) of these cases.The other vessels including antero-inferior cerebellar artery,vertebral artery, basilar artery and veins also contributed to the occurrence of NVC.The NVC sites were found to be located in the proximal segment in 42%of these cases(39/93) and in the distal segment in 45% (42/93).Nerve dislocation or distortion was observed in 32%(30/93).Conclusions:Various 3D high resolution MRI methods combined with the image fusion technique could provide pathologic anatomic information for the diagnosis and treatment of TN.展开更多
Objective:To evaluate the anatomical characteristics and patterns of neurovascular compression in patients suffering trigeminal neuralgia,using 3D high-resolution magnetic resonance imaging methods and fusion technolo...Objective:To evaluate the anatomical characteristics and patterns of neurovascular compression in patients suffering trigeminal neuralgia,using 3D high-resolution magnetic resonance imaging methods and fusion technologies.Methods:The analysis of the anatomy of the facial nerve,brain stem and the vascular structures related to this nerve was made in 100 consecutive patients for TN.3D high resolution MRI studies(3D SPGR,T1 enhanced 3D MP-RAGE and T2/T1 3D FIESTA) simultaneous visualization were used to assessed using the software 3D DOCTOR. Results:In 93 patients(93%),there were one or several locals of neurovascular compression (NVC).The superior cerebellar artery was involved in 71 cases(76%),the other vessels including the antero-inferior cerebellar artery,the basilar artery,the vertebral artery,and some venous structures.The mean distance between NVC and nerve origin site in the brainstem was(3.76±2.90) mm).In 39 patients(42%),the vascular compression was located proximally and in 42(45%) the compression was located distally.Nerve dislocation or distortion by the vessel was observed in 30 cases(32%).Conclusions:This 3D high resolution MRI and image fusion technology could be useful for diagnostic and therapeutic decisions in TN.展开更多
Objective:To detect neurovascular compression-induced structural abnormalities of trigeminal nerves(TGN) by diffusion tensor imaging(DTI).Methods:The affected ipsilateral TGN(iTGN) and unaffected contralateral TGN(cTG...Objective:To detect neurovascular compression-induced structural abnormalities of trigeminal nerves(TGN) by diffusion tensor imaging(DTI).Methods:The affected ipsilateral TGN(iTGN) and unaffected contralateral TGN(cTGN) of 20 trifacial neuralgia(TIM) patients as well as the bilateral TGN of 10 normal controls(nTGN) were examined by DTI and 3D high resolution MR] using a 3.0 T MRI scanner.The fractional anisotropy and apparent diffusion coefficieiil(ADC) were determined.Results:Compared with the cTGN and nTGN,the iTGN.had significantly lower fraction of anisotropy(FA),significantly higher ADC.and significantly smaller volume and crosssectional area(P【0.05).Conclusions:The increase in ADC and decrease in FA has a close relationship with morphological changes of TGN,and the DTI could provide valuable diagnostic information on TGN structure forTN patients.展开更多
Objective:To explore the changes in the concentrations of neural markers immediately or several months after mild traumatic brain injury(mTBI).Methods:The metabolic markers of neurons in white matter tissues above the...Objective:To explore the changes in the concentrations of neural markers immediately or several months after mild traumatic brain injury(mTBI).Methods:The metabolic markers of neurons in white matter tissues above the lateral ventricle were semi-quantitatively determined by employing 1H magnetic resonance spectroscopic technique(1-H-MRS) in 30 clinically diagnosed cases of mTBI.At the same time,the neurological functions of the subjects,including ability to pay attention,memory,working memory and operational capacity etc were also assessed. Results:The patients were followed up for,on average,13 days after mTB1 and the results showed that Cre,PCre and Glx in the white matter tissues were significantly elevated in mTBI patients.17 patients(57%) recovered from the injury during the follow-up(median was defined as the 40th post-trauma day).Comparison in terms of intelligence among groups revealed that the levels of neural markers of intelligence development was positively related with intelligence scores).Conclusions:Change in Clx concentrations is most sensitive during trauma or in ensuing repairing processes,and might be different from normal status in the following months and Clx level tends to be accompanied with change in Cre,another energy-related marker.展开更多
Objective:Late gadolinium enhancement(LGE) patterns of cardiovascular magnetic resonance (CMR) relying on PSIR(phase-sensitive inversion recovery sequence) techniques had been used to determine the characteristics of ...Objective:Late gadolinium enhancement(LGE) patterns of cardiovascular magnetic resonance (CMR) relying on PSIR(phase-sensitive inversion recovery sequence) techniques had been used to determine the characteristics of LGE in apical hypertrophic cardiomyopathy(ApHCM). Methods:Forty patients pure ApHCM[age,(60.2±10.4) years,31 men]were enrolled.LGE images were acquired using PSIR,and analyzed using a 17-segment model.Summing the LGE areas in all short axis slices yielded the total volume of late enhancement,which was subsequently presented as a proportion of total LV myocardium(%LGE).Results:Mean maximal apical wall thickness was(17.9±2.3) mm,and mean left ventricular(LV) ejection fraction was(67.7±8.0)%.LGE was detected in 130 segments of 30 patients(75.0%),occupying(4.9±5.5)% of LV myocardium.LGE was mainly detected at the junction between left and right ventricles in 12(30%) and at the apex in 28(70%),although LGE-positive areas were widely distributed,and not limited to the apex.Focal LGE at the non-hypertrophic LV segments was found in some ApHCM patients,even without LGE of hypertrophied apical segments.Conclusions:LGE was frequently observed not only in the thickened apex of the heart but also in other LV segments,irrespective of the presence or absence of hypertrophy.The simple presence of LGE on CMR was not representative of adverse prognosis in this population.展开更多
Objective:To determine the deference between phase sensitive magnetic resonance(MR) imaging and magnitude reconstruction to detect infracted myocardium.Methods:Twenty patients(16 men;4 women;mean age,56 years),experie...Objective:To determine the deference between phase sensitive magnetic resonance(MR) imaging and magnitude reconstruction to detect infracted myocardium.Methods:Twenty patients(16 men;4 women;mean age,56 years),experienced Q-wave myocardial infarction 2 weeks earlier were examined with a 3.0-T MR system 10 minutes after administration of 0.1 mmol/kg body weight gadobenate dimeglumine.To determine the optimal TI,a TI scout sequence was used.A segmented 2D IR true fast imaging with steady-state precession(trueFISP) sequence that produces both phase-sensitive and magnitude-reconstructed images were used at TI values of 200-600 msec(TI values were varied in 100-msec steps) and at optimal TI(mean value,330 msec).Contrast- noise ratios(CNRs) of normal and infarcted myocardium and the area of infarcted myocardium were determined.Two-tailed unpaired sample Student t test was used to compare CNRs,and area of infarction.Results:MMean CNR phase-sensitive and magnitude-reconstructed images at optimal TI(mean value,330 msec) were 6.2,and 6.1,respectively.For a TI of 200 msec,CNR values were 5.5,and 4.2,respectively;for TI of 600 msec,CNR values were 5.8 and 4.3,respectively.Area of infarcted myocardium was underestimated on magnitude-reconstruction images(P = 0.002-0.03) for short TI values(ie.,200 msec) but not on phase sensitive reconstructed when compared with IR tureFISP images obtained at optimal TI.Conclusions: LPhase-sensitive image reconstruction results in reduced need for precise choice of TI and more consistent image quality.展开更多
Objective:To explore the diagnostic value of mammography and MRI in breast intraductal papillary carcinoma(IDPC)and compare the diagnostic value of the two methods.Methods:Collected 28 IDPC patients who underwent mamm...Objective:To explore the diagnostic value of mammography and MRI in breast intraductal papillary carcinoma(IDPC)and compare the diagnostic value of the two methods.Methods:Collected 28 IDPC patients who underwent mammography and MRI from March 2011 to June 2019 and were confirmed by surgery and pathology.The imaging manifestations were analyzed and the accuracy of IDPC diagnosis was compared between the two methods.Results:Mammography of mammography:24 cases showed masses,3 cases showed asymmetric dense shadow with calcification,1 case showed large duct dilation in the areola area,and 6 cases showed short burrs on the edge of the tumor.MRI scan:28 cases of lesions had low signal intensity on T1WI and high signal on T2WI.19 cases showed cystic solid masses with small nodules on the cyst wall.25 cases showed obvious uneven enhancement lesions.The diagnostic accuracy of MRI was 89.3%.(25/28),the accuracy rate of mammography X-ray examination was 75.0%(21/28).There was no statistical difference in the diagnostic accuracy between the two methods,and it was not statistically significant(P=0.29).The combined use of the two inspection methods has a diagnostic accuracy rate of 96.4%.The combined two methods are more valuable than relying solely on mammography(P=0.03).Conclusion:IDPC is characterized by lobular or round masses.Large cysts with small nodules may be a special MRI manifestation of this cancer.Combining mammography and MRI can further improve the diagnosis of IDPC.展开更多
基金Supported by the Science Foundation of Haikou Health Bureau (grant No.2010-SWY-13-058)Haikou Science Technology Information Bureau (grant No.2009-049-1)
文摘Objective:To describe the anatomical characteristics and patterns of neurovascular compression (NVC) in patients suffering trigeminal neuralgia(TN) by 3D high-resolution magnetic resonance imaging(MRI) method and image fusion technique.Methods:The anatomic structure of trigeminal nerve,brain stem and blood vessel was observed in 100 consecutive TN patients by 3D high resolution MRI(3D SPGR,contrast-enhanced T1 3D MP-RAGE and T2/T1 3D FIESTA). The 3D image sources were fused and visualized using 3D DOCTOR software.Results:One or several NVC sites,which usually appeared 0-9.8 mm away from brain stem,were found on the symptomatic side in 93%of the TN cases.Superior cerebellar artery was involved in 76%(71/93) of these cases.The other vessels including antero-inferior cerebellar artery,vertebral artery, basilar artery and veins also contributed to the occurrence of NVC.The NVC sites were found to be located in the proximal segment in 42%of these cases(39/93) and in the distal segment in 45% (42/93).Nerve dislocation or distortion was observed in 32%(30/93).Conclusions:Various 3D high resolution MRI methods combined with the image fusion technique could provide pathologic anatomic information for the diagnosis and treatment of TN.
基金supported by Haikou Key Science and Technology Project (2012-075)Haikou Science Technology Information Bureau(2009-049-1)Science Foundation of Haikou Health Bureau(2010-SWY-13-058)
文摘Objective:To evaluate the anatomical characteristics and patterns of neurovascular compression in patients suffering trigeminal neuralgia,using 3D high-resolution magnetic resonance imaging methods and fusion technologies.Methods:The analysis of the anatomy of the facial nerve,brain stem and the vascular structures related to this nerve was made in 100 consecutive patients for TN.3D high resolution MRI studies(3D SPGR,T1 enhanced 3D MP-RAGE and T2/T1 3D FIESTA) simultaneous visualization were used to assessed using the software 3D DOCTOR. Results:In 93 patients(93%),there were one or several locals of neurovascular compression (NVC).The superior cerebellar artery was involved in 71 cases(76%),the other vessels including the antero-inferior cerebellar artery,the basilar artery,the vertebral artery,and some venous structures.The mean distance between NVC and nerve origin site in the brainstem was(3.76±2.90) mm).In 39 patients(42%),the vascular compression was located proximally and in 42(45%) the compression was located distally.Nerve dislocation or distortion by the vessel was observed in 30 cases(32%).Conclusions:This 3D high resolution MRI and image fusion technology could be useful for diagnostic and therapeutic decisions in TN.
基金Supported by the Science Foundation of Haikou Health Bureau (2010-SWY-13-058)Haikou Science Technology Information Bureau(2009- 049-1)
文摘Objective:To detect neurovascular compression-induced structural abnormalities of trigeminal nerves(TGN) by diffusion tensor imaging(DTI).Methods:The affected ipsilateral TGN(iTGN) and unaffected contralateral TGN(cTGN) of 20 trifacial neuralgia(TIM) patients as well as the bilateral TGN of 10 normal controls(nTGN) were examined by DTI and 3D high resolution MR] using a 3.0 T MRI scanner.The fractional anisotropy and apparent diffusion coefficieiil(ADC) were determined.Results:Compared with the cTGN and nTGN,the iTGN.had significantly lower fraction of anisotropy(FA),significantly higher ADC.and significantly smaller volume and crosssectional area(P【0.05).Conclusions:The increase in ADC and decrease in FA has a close relationship with morphological changes of TGN,and the DTI could provide valuable diagnostic information on TGN structure forTN patients.
基金aupported by Key Scientific Technological Planning Project of Haikou(No.2009-049-1)
文摘Objective:To explore the changes in the concentrations of neural markers immediately or several months after mild traumatic brain injury(mTBI).Methods:The metabolic markers of neurons in white matter tissues above the lateral ventricle were semi-quantitatively determined by employing 1H magnetic resonance spectroscopic technique(1-H-MRS) in 30 clinically diagnosed cases of mTBI.At the same time,the neurological functions of the subjects,including ability to pay attention,memory,working memory and operational capacity etc were also assessed. Results:The patients were followed up for,on average,13 days after mTB1 and the results showed that Cre,PCre and Glx in the white matter tissues were significantly elevated in mTBI patients.17 patients(57%) recovered from the injury during the follow-up(median was defined as the 40th post-trauma day).Comparison in terms of intelligence among groups revealed that the levels of neural markers of intelligence development was positively related with intelligence scores).Conclusions:Change in Clx concentrations is most sensitive during trauma or in ensuing repairing processes,and might be different from normal status in the following months and Clx level tends to be accompanied with change in Cre,another energy-related marker.
基金Supported by Haikou Key Science and Technology Project (2012-075)Haikou Science and Technology Planning Project(2009-049-1)Science and Technology Fund of Haikou Health Bureau(2010-SWY-13-058)
文摘Objective:Late gadolinium enhancement(LGE) patterns of cardiovascular magnetic resonance (CMR) relying on PSIR(phase-sensitive inversion recovery sequence) techniques had been used to determine the characteristics of LGE in apical hypertrophic cardiomyopathy(ApHCM). Methods:Forty patients pure ApHCM[age,(60.2±10.4) years,31 men]were enrolled.LGE images were acquired using PSIR,and analyzed using a 17-segment model.Summing the LGE areas in all short axis slices yielded the total volume of late enhancement,which was subsequently presented as a proportion of total LV myocardium(%LGE).Results:Mean maximal apical wall thickness was(17.9±2.3) mm,and mean left ventricular(LV) ejection fraction was(67.7±8.0)%.LGE was detected in 130 segments of 30 patients(75.0%),occupying(4.9±5.5)% of LV myocardium.LGE was mainly detected at the junction between left and right ventricles in 12(30%) and at the apex in 28(70%),although LGE-positive areas were widely distributed,and not limited to the apex.Focal LGE at the non-hypertrophic LV segments was found in some ApHCM patients,even without LGE of hypertrophied apical segments.Conclusions:LGE was frequently observed not only in the thickened apex of the heart but also in other LV segments,irrespective of the presence or absence of hypertrophy.The simple presence of LGE on CMR was not representative of adverse prognosis in this population.
基金supported by Haikou Key Science and Technology Project (2012-075)Haikou Science and Technology Planning Project(2009-049-1)Science and Technology Fund of Haikou Health Bureau(2010-SWY-13-058)
文摘Objective:To determine the deference between phase sensitive magnetic resonance(MR) imaging and magnitude reconstruction to detect infracted myocardium.Methods:Twenty patients(16 men;4 women;mean age,56 years),experienced Q-wave myocardial infarction 2 weeks earlier were examined with a 3.0-T MR system 10 minutes after administration of 0.1 mmol/kg body weight gadobenate dimeglumine.To determine the optimal TI,a TI scout sequence was used.A segmented 2D IR true fast imaging with steady-state precession(trueFISP) sequence that produces both phase-sensitive and magnitude-reconstructed images were used at TI values of 200-600 msec(TI values were varied in 100-msec steps) and at optimal TI(mean value,330 msec).Contrast- noise ratios(CNRs) of normal and infarcted myocardium and the area of infarcted myocardium were determined.Two-tailed unpaired sample Student t test was used to compare CNRs,and area of infarction.Results:MMean CNR phase-sensitive and magnitude-reconstructed images at optimal TI(mean value,330 msec) were 6.2,and 6.1,respectively.For a TI of 200 msec,CNR values were 5.5,and 4.2,respectively;for TI of 600 msec,CNR values were 5.8 and 4.3,respectively.Area of infarcted myocardium was underestimated on magnitude-reconstruction images(P = 0.002-0.03) for short TI values(ie.,200 msec) but not on phase sensitive reconstructed when compared with IR tureFISP images obtained at optimal TI.Conclusions: LPhase-sensitive image reconstruction results in reduced need for precise choice of TI and more consistent image quality.
基金Hainan province key research and development project(No.ZDYF2018175)
文摘Objective:To explore the diagnostic value of mammography and MRI in breast intraductal papillary carcinoma(IDPC)and compare the diagnostic value of the two methods.Methods:Collected 28 IDPC patients who underwent mammography and MRI from March 2011 to June 2019 and were confirmed by surgery and pathology.The imaging manifestations were analyzed and the accuracy of IDPC diagnosis was compared between the two methods.Results:Mammography of mammography:24 cases showed masses,3 cases showed asymmetric dense shadow with calcification,1 case showed large duct dilation in the areola area,and 6 cases showed short burrs on the edge of the tumor.MRI scan:28 cases of lesions had low signal intensity on T1WI and high signal on T2WI.19 cases showed cystic solid masses with small nodules on the cyst wall.25 cases showed obvious uneven enhancement lesions.The diagnostic accuracy of MRI was 89.3%.(25/28),the accuracy rate of mammography X-ray examination was 75.0%(21/28).There was no statistical difference in the diagnostic accuracy between the two methods,and it was not statistically significant(P=0.29).The combined use of the two inspection methods has a diagnostic accuracy rate of 96.4%.The combined two methods are more valuable than relying solely on mammography(P=0.03).Conclusion:IDPC is characterized by lobular or round masses.Large cysts with small nodules may be a special MRI manifestation of this cancer.Combining mammography and MRI can further improve the diagnosis of IDPC.