Sensitivity improvement of aluminum-based far-ultraviolet nearly guided-wave surface plasmon resonance sensor

An aluminum(Al)based nearly guided-wave surface plasmon resonance(NGWSPR)sensor is investigated in the far-ultraviolet(FUV)region.By simultaneously optimizing the thickness of Al and dielectric films,the sensitivity of the optimized Al-based FUV-NGWSPR sensor increases from 183/RIU to 309/RIU,and its figure of merit rises from 26.47 RIU^(-1)to 32.59 RIU^(-1)when the refractive index of dielectric increases from 2 to 5.Compared with a traditional FUV-SPR sensor without dielectric,the optimized FUV-NGWSPR sensor can realize simultaneous improvement of sensitivity and figure of merit.In addition,the FUV-NGWSPR sensor with realistic materials(diamond,Ta_(2)O_(5),and GaN)is also investigated,and 137.84%,52.70%,and 41.89%sensitivity improvements are achieved respectively.This work proposes a method for performance improvement of FUV-SPR sensors by exciting nearly guided-wave,and could be helpful for the high-performance SPR sensor in the short-wavelength region.

Dual-ion pre-inserted Mo glycerate template for constructing NiMo-OS core–shell structure with boosting performance in zinc ions hybrid supercapacitors

Zinc ion hybrid supercapacitors(ZHS)have received much attention due to the enhanced potential window range and high specific capacity.However,the appropriate positive materials with high electrochemical performance are still a challenge.Herein,NH_(4)^(+)and glycerate anions pre-inserted Mo glycerate(N-MoG)spheres are synthesized and serve as the template to form NH_(4)^(+)intercalated Ni_(3)S_(2)/Ni_(3)O_(2)(OH)_(4)@MoS_(2)core–shell nanoflower(N-NiMo-OS)in-situ grown on nickel foam(NF)(N-NiMo-OS/NF)by sulfurization treatment.Compared with the product using traditional MoG as a template,N-NiMo-OS/NF inheriting a larger core structure from N-MoG delivers enhanced space for ions transport and volume expansion during the energy storage process,together with the synergistic effects of multi-components and the heterostructure,the as-prepared N-NiMo-OS/NF nanoflower exhibits excellent performance for the battery-type hybrid supercapacitors(BHS)and ZHS devices.Notably,the ZHS device delivers superior electrochemical performance to the BHS device,such as a higher specific capacity of 327.5 mAh·g^(−1)at 1 A·g^(−1),a preeminent energy density of 610.6 Wh·kg^(−1)at 1710 W·kg^(−1),long cycle life.The in-situ Raman,ex-situ X-ray photoelectron spectroscopy(XPS),theoretical calculation demonstrate the extra Zn^(2+)insertion/extraction storage mechanism provides enhanced electrochemical performance for ZHS device.Therefore,the dual-ion pre-inserted strategy can be extended for other advanced electrode materials in energy storage fields.

基于AMPK信号通路探讨活血荣络方对缺氧缺血性脑损伤大鼠的保护作用

目的探讨活血荣络方对缺氧缺血性脑损伤(HIBD)大鼠的保护作用, 明确HIBD损伤及修复过程中AMPK信号通路的表达情况。方法在缺氧缺血再灌注模型基础上采用改良缺氧瓶建立足月HIBD大鼠模型。将造模成功60只大鼠按随机数字表法分为模型组和中药组, 每组30只, 另设对照组30只。术前2 h中药组灌胃活血荣络方水煎液1.17 g/100 g(等效剂量), 对照组和模型组灌胃等体积生理盐水, 术后2 h再灌胃1次, 2次/d, 连续灌胃5 d。采用行为学测试(惊厥评估、Longa评分、悬吊实验、水迷宫实验)评估各组大鼠运动神经功能情况和远期学习能力, HE染色与电镜观察脑组织病理结构变化和线粒体损伤情况, 伊文思蓝染色与脑含水量测定用于检测血脑屏障通透性和脑水肿情况, PCR阵列技术检测各组大鼠脑组织中AMPK信号通路相关基因表达情况。结果与模型组比较, 中药组大鼠惊厥发作有所改善、Longa评分降低、握力测试评分与悬吊时间提升、逃避潜伏期缩短、穿越平台次数增加(P<0.05);中药组神经元与线粒体损伤程度减轻, 脑血管通透性与脑含水量降低(P<0.01)。PCR阵列结果显示, 与对照组比较, 模型组脑组织中有2个基因显著上调, 12个基因显著下调;与中药组比较, 模型组有15个基因相对下调。结论活血荣络方可减轻HIBD大鼠脑损伤程度, 改善运动神经功能和提高学习认知能力, 其损伤修复机制与调控AMPK信号通路相关基因表达有关。