Associations between individual and environmental factors and habitual physical activity among older Chinese adults:A social–ecological perspective

Purpose: To examine, within a social–ecological framework, associations between multifaceted individual and environmental factors and habitual physical activity(HPA) among older Chinese adults.Methods: Through a mix of qualitative and quantitative methods, a survey instrument assessing various factors underlying 3 social–ecological dimensions of intrapersonal, interpersonal, and community and environmental resources was developed. Using a cross-sectional design, older adults(n = 1580, aged 67 ± 7 years) recruited from 10 communities in Shandong province completed the social–ecological survey of HPA. Data were analyzed using Partial Least Squares Path Modeling.Results: Factors related to intrapersonal(medical knowledge, motivation, physical function, sport skills, socioeconomic status, and education),interpersonal(social support, social activity, and social norms), and community and physical environmental resources(safety, capacity, availability of and access to physical activity facilities) were found to be significantly associated with older adults' participation in HPA.Conclusion: The findings provide an initial validation of a social–ecological approach to the study of HPA in China, suggesting that strategies aimed at promoting physical activity in older adults should address multiple levels of factors that may contribute to the likelihood of older Chinese adults being physically active.

Mechanism Analysis of Stiffness Improvement by Waterborne Epoxy Resin Surface Sizing Agent

Low-basis-weight paper lacks normal strength and stiffness. Waterborne epoxy resin could be employed with oxidized starch to improve paper stiffness through surface sizing. In this study,the mechanism of enhancing stiffness by adding waterborne epoxy resin was fully investigated. The results indicated that through surface sizing with epoxy resin,the paper thickness was preserved,whereas the elastic modulus increased significantly and the epoxy resin had positive impact on single fiber strength. A rigid resin layer and interpenetrating polymer network formed on the surface and in the inner layer of the paper,respectively. The formed resin layer and interpenetrating polymer network strongly supported the paper,leading to the improvement of the elastic modulus and stiffness. The stiffness improvement through surface sizing was mainly due to the formation of a fibrous composite layer and penetration of the sizing agent into the inner layers of the paper. The better the combination between fiber and sizing agent,the higher were the elastic modulus and the stiffness of the whole paper.

More than a Few LAB Alleviate Common Allergies: Impact of Paraprobiotics in Comparison to Probiotical Live Cells

The evidence in this paper indicates that the alarming increase of common allergies can be reduced by the intake of particular “probiotics” or “paraprobiotics” along with food. This appears to build a consensus in the pharmaceutical and food communities about the role of probiotics in the prevention and treatments of common allergies. Food allergy is one of the common allergies, defined as an adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food. Improving the digestion of foods and maintaining a healthy gastrointestinal (GI) tract is certainly critical to controlling food allergens. Therefore, the association between a leaky gut or an impaired intestinal permeability and food-allergenic reactions is explained. Gluten has been found to be somehow a justification for protein allergy, and should, therefore, be avoided by people with celiac disease. In several, in vitro models, surface layer (S- layer) proteins of selective paraprobiotics have shown potential in alleviating food allergies and intestinal disorders. Notably, lactobacilli paraprobiotics have proven to be the immediate immunomodulators against common allergies and other diseases, including viral (flu, hepatitis C), bacterial (bronchitis), asthma, chronic fatigue, fibromyalgia, gastrointestinal distress, and autism disorders in humans.

Prevention and Treatment of COVID-19 and Rehabilitation of Kidney,Liver and Cardiovascular Diseases with Kyllinga brevifolia Rottb.

The COVID-19 epidemic is raging,and the virus damages the lung,kidney,liver,and cardiovascular system.Medicine for prevention and treatment of COVID-19 requires three properties:being able to efficiently inhibit COVID-19 from infecting cells;being able to quickly repair lung damage;non-toxic.Kyllinga brevifolia Rottb.is found to have the three properties mentioned above and can be used for prevention,treatment and rehabilitation.In terms of rehabilitation of lung,kidney,liver,and cardiovascular diseases,K.brevifolia Rottb.shows remarkable efficacy when combined with other medicinal materials.This is instructive and useful for the rehabilitation of lung,liver,kidney,and cardiovascular damage caused by COVID-19.

Clinical Effect of Comprehensive Rehabilitation Treatment for Deep Burns in Different Functional Joint Areas

Objective:To analyse the clinical effect of comprehensive rehabilitation therapy in patients with deep burns at different functional joint areas.Methods:Eighty-one patients with deep burns with different functional joint areas from April 2018 to April 2019 were divided into the conventional and rehabilitation groupings.The conventional group(n=40)received routine treatment and rehabilitation while the rehabilitation group(n=41)was given comprehensive rehabilitation treatment.Thereafter,the recovery of joint function in patients with deep burns in different areas,the combined value of clinical long-term treatment,the recovery of joint function and the score of daily living ability were calculated.Results:The total long-term effective rate of treatment,the recovery of the joint function,and the score of daily living ability of the patients with deep burns in the rehabilitation group were more favourable than those of the conventional group as demonstrated by P<0.05,the index data indicating statistical significance.Conclusion:Comprehensive rehabilitation therapy can reduce complications and improve the quality of life in patients with deep burns in different functional joint areas.

Parvovirus B19 infection and B-cell response pattern in unexplained lymphadenopathy

Lymphadenopathy is defined as lymph nodes(LN)that are abnormal in size or consistency,usually with a diameter>1 cm.Common etiologies include malignancy,infection,autoimmune disorders,and medications.[1]Most patients obtain a definite diagnosis after undergoing a series of examinations.However,the etiology remains unclear in a small number of patients.

Effective methods for isolation and purification of extracellular vesicles from plants

Plant extracellular vesicles(EVs)play critical roles in the cross-kingdom trafficking of molecules from hosts to interacting microbes,most notably in plant defense responses.However,the isolation of pure,intact EVs from plants remains challenging.A variety of methods have been utilized to isolate plant EVs from apoplastic washing fluid(AWF).Here,we compare published plant EV isolation methods,and provide our recommended method for the isolation and purification of plant EVs.This method includes a detailed protocol for clean AWF collection from Arabidopsis thaliana leaves,followed by EV isolation via differential centrifugation.To further separate and purify specific subclasses of EVs from heterogeneous vesicle populations,density gradient ultracentrifugation and immunoaffinity capture are then utilized.We found that immunoaffinity capture is the most precise method for specific EV subclass isolation when suitable specific EV biomarkers and their corresponding antibodies are available.Overall,this study provides a guide for the selection and optimization of EV isolation methods for desired downstream applications.

牡丹皮炭化学成分及其潜在凝血活性研究（英文）

对中药牡丹皮炭的化学成分进行深入研究,并对其凝血活性进行筛选。通过聚酰胺、硅胶、葡聚糖凝胶等柱色谱方法进行分离纯化,利用核磁共振波谱等方法鉴定结构。共分离鉴定了10个化合物,分别为3-(2-呋喃)-1-(2-羟基-4-甲氧基苯基)-2-丙烯酮(1)、2-(2,5-羟基-4-甲基苯基)丙酸乙酯(2)、5-十四烯酸甲酯(3)、1,4-二乙基-环己烷(4)、儿茶酚(5)、对羟基苯甲酸甲酯(6)、3-羟基-2-甲基-4-吡喃酮(7)、3,8-二羟基-2-甲基色酮(8)、3β-羟基-齐墩果烷-12-烯(9)、1-亚油酸单甘油酯(10)。其中1, 2为新天然产物, 3–10为首次从牡丹皮炭中分离得到。在体外评估化合物潜在的凝血活性,化合物2, 9和10具有强烈的止血作用,而化合物1和8可以活化血液循环。