Objective The present study aims to identify the clinicopathologic factors predictive of lymph node metastasis(LNM) in poorly differentiated early gastric cancer(EGC) and to expand the possibility of using laparoscopi...Objective The present study aims to identify the clinicopathologic factors predictive of lymph node metastasis(LNM) in poorly differentiated early gastric cancer(EGC) and to expand the possibility of using laparoscopic surgery for the treatment of poorly differentiated EGC. Methods Data from 70 cases of poorly differentiated EGC treated with surgery were collected.The association between clinicopathologic factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Results Univariate analysis showed that tumor size,depth of invasion,and lymphatic vessel involvement(LVI) were the significant and independent risk factors for LNM(all P<0.05).The LNM rates were 6.9%,45.5%,and 60.0%,respectively.There was no LNM in 25 patients without the above three risk factors. Conclusions Laparoscopic surgery is a sufficient treatment for intramucosal poorly differentiated EGC if the tumor is less than or equal to 2.0 cm in size and when LVI is absent upon postoperative histological examination.展开更多
基金supported by the Science Foundation of Xingtai City,China(No.20102025-2)
文摘Objective The present study aims to identify the clinicopathologic factors predictive of lymph node metastasis(LNM) in poorly differentiated early gastric cancer(EGC) and to expand the possibility of using laparoscopic surgery for the treatment of poorly differentiated EGC. Methods Data from 70 cases of poorly differentiated EGC treated with surgery were collected.The association between clinicopathologic factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Results Univariate analysis showed that tumor size,depth of invasion,and lymphatic vessel involvement(LVI) were the significant and independent risk factors for LNM(all P<0.05).The LNM rates were 6.9%,45.5%,and 60.0%,respectively.There was no LNM in 25 patients without the above three risk factors. Conclusions Laparoscopic surgery is a sufficient treatment for intramucosal poorly differentiated EGC if the tumor is less than or equal to 2.0 cm in size and when LVI is absent upon postoperative histological examination.
