To the Editor:Neuropsychiatric systemic lupus erythematosus(NPSLE)is a group of serious complications of systemic lupus erythematosus(SLE)with poor prognosis and high mortality.^([1])Therefore,identifying risk factors...To the Editor:Neuropsychiatric systemic lupus erythematosus(NPSLE)is a group of serious complications of systemic lupus erythematosus(SLE)with poor prognosis and high mortality.^([1])Therefore,identifying risk factors for NPSLE is particularly crucial for the improvement of the outcomes of patients.Magnetic resonance imaging(MRI)is currently the imaging test of choice for diagnosing patients with NPSLE.However,almost half of the patients with NPSLE show no abnormalities on conventional MRI.^([2])Therefore,the correlation between neuropsychiatric symptoms,which refer to multiple neuropsychiatric manifestations directly related to SLE,and MRI findings should be urgently studied.In this study,we investigated the clinical features,outcomes,and prognostic factors of NPSLE and analyzed the correlation of neuropsychiatric symptoms with MRI features.展开更多
基金supported by grants from the National Natural Science Foundation of China(No.82271847)Hubei Provincial Natural Science Foundation Joint Fund for Innovation and Development Project(No.2023AFD046)Tongji Hospital Scientific Research Fund(No.2022B09)
文摘To the Editor:Neuropsychiatric systemic lupus erythematosus(NPSLE)is a group of serious complications of systemic lupus erythematosus(SLE)with poor prognosis and high mortality.^([1])Therefore,identifying risk factors for NPSLE is particularly crucial for the improvement of the outcomes of patients.Magnetic resonance imaging(MRI)is currently the imaging test of choice for diagnosing patients with NPSLE.However,almost half of the patients with NPSLE show no abnormalities on conventional MRI.^([2])Therefore,the correlation between neuropsychiatric symptoms,which refer to multiple neuropsychiatric manifestations directly related to SLE,and MRI findings should be urgently studied.In this study,we investigated the clinical features,outcomes,and prognostic factors of NPSLE and analyzed the correlation of neuropsychiatric symptoms with MRI features.
