Allenes are a class of unsaturated compounds containing a propadiene structural moiety,exhibiting essential physiological,pharmacological,and various reactivities.Their(4þ3)cycloaddition reaction has become an ef...Allenes are a class of unsaturated compounds containing a propadiene structural moiety,exhibiting essential physiological,pharmacological,and various reactivities.Their(4þ3)cycloaddition reaction has become an effective method for synthesizing seven-membered rings,especially for heterocycles.This method has been continuously improved and developed.Herein,we review the(4þ3)cycloaddition of allenes,focusing on the developed methodologies and the outlook in this field from 2013 to 2023.展开更多
基金financial support from the supported by National Natural Science Foundation of China(Nos.22061008 and 22361008)the State Key Laboratory of Natural and Biomimetic Drugs(No.K202223)+1 种基金the Science and Technology Foundation of Guizhou Province(Nos.ZK[2021]-039 and[2023]-097)the State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Medical University(No.FAMP202102K).
文摘Allenes are a class of unsaturated compounds containing a propadiene structural moiety,exhibiting essential physiological,pharmacological,and various reactivities.Their(4þ3)cycloaddition reaction has become an effective method for synthesizing seven-membered rings,especially for heterocycles.This method has been continuously improved and developed.Herein,we review the(4þ3)cycloaddition of allenes,focusing on the developed methodologies and the outlook in this field from 2013 to 2023.
