Application of Three-Dimensional Magnetic Resonance Imaging in the Diagnosis of Perianal Abscess

Perianal abscess is a common disease in anorectal surgery. If the diagnosis is not clear and the cure is thoroughly cleared, the recurrence and spread of anal fistula will cause life-long pain. Objective: To investigate the application of 3.0T MRI 3D CUBE T2WI lipid suppression sequence in the diagnosis of perianal abscess. Methods: Thirty-six patients with perianal abscess confirmed by operation were examined with 2D T2WI and 3D CUBE T2WI lipid suppression sequences before operation. Two imaging techniques were evaluated to show the types of perianal abscess, the number of abscesses, the number of internal orifices of abscess, and the number of fistula branches with anal fistula in abscess. Results: Among 36 cases of perianal abscess, there were 5 cases of anal subcutaneous abscess, 12 cases of ischiorectal space abscess (8 cases complicated with anal fistula), 6 cases of posterior anal space abscess, 5 cases of anal sphincter abscess (3 cases complicated with anal fistula), 2 cases of high intermuscular abscess, 2 cases of rectal submucosal abscess, 3 cases of complex abscess (3 cases complicated with anal fistula), 1 case of misdiagnosis, 2D T2WI lipid suppression sequence and 3D CUBE T2WI suppression. The accuracy of lipid sequence abscess typing was 80.6% (29/36) and 88.9% (32/36), respectively, with no significant difference (P > 0.05). Thirty-six patients were surgically diagnosed as having 32 internal orifices, 68.8% (22/32) and 93.8% (30/32) of 2D T2WI and 3D CUBE T2WI lipid-suppressing sequences, respectively, with significant difference (P Conclusion: 3D CUBE T2WI lipid suppression sequence is superior to 2D T2WI lipid suppression sequence in the classification of perianal abscess, the number of internal orifices of abscess and the number of fistula branches of abscess complicated with anal fistula. It can also determine the number of internal orifices of abscess complicated with anal fistula, the number of fistula branches, the shape of primary and branch fistula and the relationship among pelvic floor muscle tissues. It can provide more accurate images for preoperative and intraoperative clinical surgery.

The double intervention clinical value and application research of TACE with PAI on massive hepatocellular carcinoma

Objective:To study the efficacy of transcatheter arterial chemoembolization(TACE) combined with percutaneous acetic acid injection(PAI) on massive hepatocellular carcinoma(MHCC). Methods:TACE was performed in 57 patients with MHCC,which were randomly divided into group A(n = 28) and group B(n = 29). Patients in the group A received conventional TACE for the first time and then received low dose TACE(10 mg mitomycin C) for the repeated treatment,Re-examined CT scans after TACE for a week. Based on filled status of Lipiodol in the Lesions,PAI was underwent in the area of rarefaction or defect filled by Lipiodol. Patients in the group B received conventional TACE. Then The survival rate and masses variation and hepatic function and α-FP and side effects were observed. Results:The 1-,2-and 3-year survival rate after TACE were 96.4%,78.6% and 32.1% for group A,and 65.5%,48.3% and 20.7% for group B. Masses diminution were found in all patients in group A,while 20 cases were found in group B,unchanged in 5 cases and enlarged in 4 cases. Conclusion:The efficacy of TACE combined with PAI are significantly better than that of TACE only,low dose TACE produces less hepatic damage and less side effect.

Advances in Assessing Preoperative Liver Function with Gd-EOB-DTPA Dynamic Contrast Enhanced MRI

Liver cancer is the common malignant tumor in China and current treatment is based on surgery. However, liver function of many liver cancer patients is impaired before surgery, so there’s a high possibility of occurrence of liver failure after the tumor resection. Therefore, it’s necessary to accurately evaluate liver function before surgery. Currently, clinical methods are mostly limited to assess the function of overall liver. But the application of hepatocyte-specific contrast agent—gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) makes it possible to assess the function of local liver segment accurately. This paper reviewed the progress of using Gd-EOB-DTPA dynamic contrast enhanced magnetic resonance imaging (MRI) to assess liver function preoperatively, such as parameters selection for liver function assessment, clinical factors affecting Gd-EOB-DTPA enhanced MRI and so on.

Progresses of Functional Magnetic Resonance Imaging Diagnosis in Breast Cancer

Breast cancer is the most common malignant tumor that threatens women’s health. Breast magnetic resonance imaging (MRI) is a commonly used method recommended for the diagnosis of breast cancer. Diffusion weighted imaging (DWI) and dynamic enhanced magnetic resonance imaging (DCE-MRI) are now widely used. At present, with the continuous advancement of magnetic resonance technology, Magnetic resonance spectroscopy (MRS), Perfusion weighted imaging (PWI), Positron emission tomography-magnetic resonance imaging (PET-MRI) and so on are gradually being used in clinical practice. Mammography imaging and imaging genomics are hot topics. This article will briefly introduce several functional magnetic resonance techniques and their latest applications.