Hepatic myelopathy(HM)is a rare neurological complication in the end stage of many liver diseases and is characterized by bilateral spastic paraparesis without sensory and sphinc-ter dysfunction.It occurs owing to met...Hepatic myelopathy(HM)is a rare neurological complication in the end stage of many liver diseases and is characterized by bilateral spastic paraparesis without sensory and sphinc-ter dysfunction.It occurs owing to metabolic disorders and central nervous system dysfunction associated with cirrhosis.Without timely and effective clinical intervention,the progno-sis of these patients is devastating.Although liver transplan-tation(LT)is an effective treatment for HM,the prognosis of these patients remains unsatisfactory.Early recognition and diagnosis of this disease are essential for improving patient prognosis.Here,we report a case of hepatitis B virus-asso-ciated decompensated cirrhosis with HM.The patient recov-ered well after LT.We also summarize the clinical character-istics and post-transplant outcomes of 25 patients with HM treated by LT through 2023,including this case.展开更多
基金supported by The National Natural Scientific Foundation of China(Grant No.81972230).
文摘Hepatic myelopathy(HM)is a rare neurological complication in the end stage of many liver diseases and is characterized by bilateral spastic paraparesis without sensory and sphinc-ter dysfunction.It occurs owing to metabolic disorders and central nervous system dysfunction associated with cirrhosis.Without timely and effective clinical intervention,the progno-sis of these patients is devastating.Although liver transplan-tation(LT)is an effective treatment for HM,the prognosis of these patients remains unsatisfactory.Early recognition and diagnosis of this disease are essential for improving patient prognosis.Here,we report a case of hepatitis B virus-asso-ciated decompensated cirrhosis with HM.The patient recov-ered well after LT.We also summarize the clinical character-istics and post-transplant outcomes of 25 patients with HM treated by LT through 2023,including this case.
