A number of effective therapies for the treatment of osteoporosis have become available in recent years. However, uncertainty exists regarding their long-term use and effectiveness. Bisphosphonate treatment, unlike ho...A number of effective therapies for the treatment of osteoporosis have become available in recent years. However, uncertainty exists regarding their long-term use and effectiveness. Bisphosphonate treatment, unlike hormone replacement, denosumab or teriparatide, is associated with benefits extended even after treatment discontinuation. The extended benefits are most apparent for alendronate （ALN） and zoledronate （ZOL）. A drug holiday might be considered in patients compliant with treatment, and who have had a response fractures the decision to consider a drug holiday should treatment. at low-moderate risk and who have been fully to treatment. In patients at low-moderate risk of be balanced also with the safety profile of each展开更多
文摘A number of effective therapies for the treatment of osteoporosis have become available in recent years. However, uncertainty exists regarding their long-term use and effectiveness. Bisphosphonate treatment, unlike hormone replacement, denosumab or teriparatide, is associated with benefits extended even after treatment discontinuation. The extended benefits are most apparent for alendronate （ALN） and zoledronate （ZOL）. A drug holiday might be considered in patients compliant with treatment, and who have had a response fractures the decision to consider a drug holiday should treatment. at low-moderate risk and who have been fully to treatment. In patients at low-moderate risk of be balanced also with the safety profile of each
