1 Introduction Kounis syndrome constitutes a coronary hypersensitivity disorder defined by the association of an anaphylactoid,anaphylactic,allergic or hypersensitivity reaction with an acute coronary syndrome,in a ph...1 Introduction Kounis syndrome constitutes a coronary hypersensitivity disorder defined by the association of an anaphylactoid,anaphylactic,allergic or hypersensitivity reaction with an acute coronary syndrome,in a physiopathological context involving various interrelated and interacting inflammatory cells,such as mast-cells,eosinophils and platelets.[1,2]Similar entities to Kounis syndrome might involve cerebral and mesenteric arteries.展开更多
COVID-19 pandemic continues to strike across the world with increasing number of infected patients,severe morbidity and mortality,social life and economy disruption.Universal access to vaccine prophylaxis will be pivo...COVID-19 pandemic continues to strike across the world with increasing number of infected patients,severe morbidity and mortality,social life and economy disruption.Universal access to vaccine prophylaxis will be pivotal in controlling this infection and providing individual level protection.However,mismatch between vaccine request and vaccine availability,as well as constraints in logistics of vaccine campaign is creating a transition phase of progressive but still incomplete inclusion of group of individuals in the vaccination process.Selected patients living with chronic and multisystemic disease may present increased propensity of adverse outcome,should Sars-Cov-2 infection develop.In these patients,expedite access to COVID-19 vaccination may be considered.The Italian Society of Pediatric Cardiology National Board is providing a viewpoint to inform policy makers and public authorities during vaccine allocation strategies development,to consider higher priority and expedite access for selected groups of patients living with congenital heart disease.展开更多
文摘1 Introduction Kounis syndrome constitutes a coronary hypersensitivity disorder defined by the association of an anaphylactoid,anaphylactic,allergic or hypersensitivity reaction with an acute coronary syndrome,in a physiopathological context involving various interrelated and interacting inflammatory cells,such as mast-cells,eosinophils and platelets.[1,2]Similar entities to Kounis syndrome might involve cerebral and mesenteric arteries.
文摘COVID-19 pandemic continues to strike across the world with increasing number of infected patients,severe morbidity and mortality,social life and economy disruption.Universal access to vaccine prophylaxis will be pivotal in controlling this infection and providing individual level protection.However,mismatch between vaccine request and vaccine availability,as well as constraints in logistics of vaccine campaign is creating a transition phase of progressive but still incomplete inclusion of group of individuals in the vaccination process.Selected patients living with chronic and multisystemic disease may present increased propensity of adverse outcome,should Sars-Cov-2 infection develop.In these patients,expedite access to COVID-19 vaccination may be considered.The Italian Society of Pediatric Cardiology National Board is providing a viewpoint to inform policy makers and public authorities during vaccine allocation strategies development,to consider higher priority and expedite access for selected groups of patients living with congenital heart disease.
