More than any other organs,brain energy demand is entirely dependent on glucose catabolism through the oxidative phosphorylation（OXPHOS）.Glucose is the major cerebral energy substrate in the nervous system（NS）.Ket...More than any other organs,brain energy demand is entirely dependent on glucose catabolism through the oxidative phosphorylation（OXPHOS）.Glucose is the major cerebral energy substrate in the nervous system（NS）.Ketone bodies can be utilized as an additional substrate,but in any case,neurons critically depend on oxygen supply.展开更多
基金Grant from the"Fondazione Giuseppe Levi–Accademia Nazionale dei Lincei"for the research project entitled:"Produzione extramitocondriale di ATP in mielina:localizzazione dei complessi della catena respiratoria e possible ruolo nella degenerazione assonale in Sclerosi Multipla",No.Borsa"Giuseppe Levi"_2013the‘‘Compagnia di San Paolo’’-Neuroscience Program,for the research project entitled:‘‘Energetic metabolism in myelinated axon:a new trophic role of myelin sheath’’,No.2008.1142
文摘More than any other organs,brain energy demand is entirely dependent on glucose catabolism through the oxidative phosphorylation（OXPHOS）.Glucose is the major cerebral energy substrate in the nervous system（NS）.Ketone bodies can be utilized as an additional substrate,but in any case,neurons critically depend on oxygen supply.
