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Adult neurogenesis in the mammalian brain 被引量:1
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作者 simon m.g. braun Sebastian JESSBERGER 《Frontiers in Biology》 CAS CSCD 2013年第3期295-304,共10页
New neurons are generated throughout life in distinct areas of the mammalian brain. This process, called adult neurogenesis, has challenged previously held concepts about adult brain plasticity and opened novel therap... New neurons are generated throughout life in distinct areas of the mammalian brain. This process, called adult neurogenesis, has challenged previously held concepts about adult brain plasticity and opened novel therapeutic avenues to treat certain neuro-psychiatric diseases. Here, we review the current knowledge regarding the fate and potency of neural stem cells (NSCs), as well as the mechanisms underlying neuronal differentiation and subsequent integration. Furthermore, we discuss the functional significance of adult neurogenesis in health and disease, and offer brief insight into the future directions of the adult neurogenesis field. 展开更多
关键词 adult neurogenesis HIPPOCAMPUS stem cell MEMORY neuropsychiatric disease
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