The Strecker reaction was performed via a one-pot three component condensation of hetero aromatic/ aromatic aldehydes, secondary amines and trimetylsilyl cyanide in the presence of propylphosphonic anhydride (T3P) t...The Strecker reaction was performed via a one-pot three component condensation of hetero aromatic/ aromatic aldehydes, secondary amines and trimetylsilyl cyanide in the presence of propylphosphonic anhydride (T3P) to accomplish the corresponding α-aminonitriles. The main advantages of this method are very short reaction time and excellent yields.展开更多
基金the Board of Research in Nuclear Sciences (BRNS),Mumbai,India for providing the financial support (No.2012/37C/33/BRNS)
文摘The Strecker reaction was performed via a one-pot three component condensation of hetero aromatic/ aromatic aldehydes, secondary amines and trimetylsilyl cyanide in the presence of propylphosphonic anhydride (T3P) to accomplish the corresponding α-aminonitriles. The main advantages of this method are very short reaction time and excellent yields.