期刊文献+
共找到4篇文章
< 1 >
每页显示 20 50 100
The effects of hyperbaric oxygen therapy on paroxysmal sympathetic hyperactivity after cardiopulmonary resuscitation: a case series
1
作者 Hongyu Wang Yihao Li +2 位作者 Meng Zhao Caihong Ren sisen zhang 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2023年第6期477-480,共4页
The onset of cardiac arrest (CA) is sudden and critical.Due to cerebral ischaemia and hypoxia, the prognosis for post-cardiopulmonary resuscitation (CPR) patients is poor. Paroxysmal sympathetic hyperexcitability (PSH... The onset of cardiac arrest (CA) is sudden and critical.Due to cerebral ischaemia and hypoxia, the prognosis for post-cardiopulmonary resuscitation (CPR) patients is poor. Paroxysmal sympathetic hyperexcitability (PSH) is a potentially life-threatening condition, which is characterized by episodes of increased heart rate and blood pressure,sweating, hypothermia, and forced posture.[1] Hypoxicischaemic encephalopathy post-CPR can lead to PSH,which often indicates a worse prognosis. 展开更多
关键词 SYMPATHETIC RESUSCITATION PROGNOSIS
下载PDF
CDA基因变异对卡培他滨治疗结直肠癌患者出现手足综合征的影响 被引量:8
2
作者 李荣振 张思森 +2 位作者 杨铁健 季节 沈杰 《中国肿瘤临床》 CAS CSCD 北大核心 2018年第9期458-461,共4页
目的:探讨胞苷脱氨酶(cytidine deaminase,CDA)基因变异对接受含卡培他滨方案治疗的结直肠癌患者的3级手足综合征(hand-foot syndrome,HFS)的影响。方法:选取2014年5月至2017年5月在郑州人民医院接受卡培他滨治疗的结直肠癌患者149例,... 目的:探讨胞苷脱氨酶(cytidine deaminase,CDA)基因变异对接受含卡培他滨方案治疗的结直肠癌患者的3级手足综合征(hand-foot syndrome,HFS)的影响。方法:选取2014年5月至2017年5月在郑州人民医院接受卡培他滨治疗的结直肠癌患者149例,对卡培他滨代谢通路上的关键基因CDA进行基因分型,对分型的位点和HFS发生的相关性进行分析。另外,从全部患者中随机选取91例患者的外周血单核细胞(peripheral blood mononuclear cell,PBMC)提取RNA,对CDA的mRNA表达水平进行测定,并结合多态性位点进行分析。结果:位于CDA基因启动子区域的多态性位点-451G>A与HFS相关。基因分型结果为GG型109例(73.15%),GA型38例(25.50%),AA型2型(1.36%),最小等位基因频率为0.14,三种基因型分布频率符合哈迪温伯格平衡(P=0.516)。相关性分析发现-451G>A位点GA/AA型患者与HFS的发生显著相关(OR=2.53,P=0.014)。另外,位于CDA基因启动子区域的插入变异-33delC和-451C>T呈现高度的连锁不平衡(D'=0.92)。在91例PBMC当中提取的RNA表达分析结果表明,-451G>A位点GA/AA型患者的CDA m RNA表达水平显著高于野生型GG型患者(4.01±0.53 vs.3.13±0.61,P<0.001)。结论:TAM的-451G>A多态性位点可能通过介导CDA基因mRNA的表达从而影响卡培他滨引起的HFS。 展开更多
关键词 卡培他滨 胞苷脱氨酶 多态性 手足综合征
下载PDF
Expert consensus on prevention and cardiopulmonary resuscitation for cardiac arrest in COVID-19
3
作者 Wei Song Jie Wei +42 位作者 Xiangdong Jian Deren Wang Yanhong Ouyang Yuanshui Liu Xianjin Du Ying Chen Yingqi zhang Heping Xu Shuming Xianyu Qiong Ning Xiang Li Xiaotong Han Feng Zhan Tao Yu Wenteng Chen Jun zhang Wenwei Cai Sheng’ang Zhou Shengyang Yi Yu Cao Xiaobei Chen Shunjiang Xu Zong’an Liang Duohu Wu Fen Ai Zhong Wang Qingyi Meng Yuhong Mi sisen zhang Rongjia Yang Shouchun Yan Wenbin Han Yong Lin Chuanyun Qian Wenwu zhang Yan Xiong Jun Lv Baochi Liu Yan Cao Xiaojun He Xuelian Sun Yufang Cao Tian’en Zhou 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2021年第6期241-253,共13页
Background:Cardiopulmonary resuscitation(CPR)strategies in COVID-19 patients differ from those in patients suffering from cardiogenic cardiac arrest.During CPR,both healthcare and non-healthcare workers who provide re... Background:Cardiopulmonary resuscitation(CPR)strategies in COVID-19 patients differ from those in patients suffering from cardiogenic cardiac arrest.During CPR,both healthcare and non-healthcare workers who provide resuscitation are at risk of infection.The Working Group for Expert Consensus on Prevention and Cardiopulmonary Resuscitation for Cardiac Arrest in COVID-19 has developed this Chinese Expert Consensus to guide clinical practice of CPR in COVID-19 patients.Main recommendations:1)A medical team should be assigned to evaluate severe and critical COVID-19 for early monitoring of cardiac-arrest warning signs.2)Psychological counseling and treatment are highly recommended,since sympathetic and vagal abnormalities induced by psychological stress from the COVID-19 pandemic can induce cardiac arrest.3)Healthcare workers should wear personal protective equipment(PPE).4)Mouth-to-mouth ventilation should be avoided on patients suspected of having or diagnosed with COVID-19.5)Hands-only chest compression and mechanical chest compression are recommended.6)Tracheal-intubation procedures should be optimized and tracheal-intubation strategies should be implemented early.7)CPR should be provided for 20-30 min.8)Various factors should be taken into consideration such as the interests of patients and family members,ethics,transmission risks,and laws and regulations governing infectious disease control.Changes in management:The following changes or modifications to CPR strategy in COVID-19 patients are proposed:1)Healthcare workers should wear PPE.2)Hands-only chest compression and mechanical chest compression can be implemented to reduce or avoid the spread of viruses by aerosols.3)Both the benefits to patients and the risk of infection should be considered.4)Hhealthcare workers should be fully aware of and trained in CPR strategies and procedures specifically for patients with COVID-19. 展开更多
关键词 SARS-CoV-2 COVID-19 Cardiac arrest CPR Nosocomial infection Personal protective equipment
下载PDF
基于郑州局地疫情暴发重大突发公卫事件医疗机构应对“平疫转换”感染防控策略 被引量:3
4
作者 张枭然 张思森 +7 位作者 王胜 阎颖 刘娟 孙渭歌 刘琛 王文文 张亚琴 郝义彬 《中华卫生应急电子杂志》 2021年第5期264-268,共5页
新型冠状病毒病2019(coronavirus disease 2019,COVID- 19)已成为我国面临的最大突发公共卫生事件。截止2021年8月18日,我国COVID- 19累计报告确诊患者94 546例^([1])。由于COVID- 19传染性强,医疗机构面临的院内感染风险较高,稍有不慎... 新型冠状病毒病2019(coronavirus disease 2019,COVID- 19)已成为我国面临的最大突发公共卫生事件。截止2021年8月18日,我国COVID- 19累计报告确诊患者94 546例^([1])。由于COVID- 19传染性强,医疗机构面临的院内感染风险较高,稍有不慎就容易出现聚集性疫情。在早期疫情救治过程中,出现较多医务人员感染并死亡,曾引起广泛关注^([2- 3])。 展开更多
关键词 防控策略 突发公共卫生事件 医疗机构 院内感染 疫情暴发 确诊患者
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部